WHEATGRASS: A COMPREHENSIVE REVIEW ON ITS THERAPEUTIC POTENTIAL
Main Article Content
Keywords
Wheatgrass, Chlorophyll, Green Blood, Anti-oxidant, Anti-cancer, Anti-diabetic
Abstract
Wheatgrass is the young grass of Triticum aestivum Linn. Due to its extraordinary medicinal properties, it has become a vital part of traditional medicine, especially in Indian culture. It contains various bioactive compounds, including flavonoids, amino acids, chlorophyll, and essential vitamins and minerals, which makes it a nutritional powerhouse. Mostly it is consumed as juice, powder, tablets, etc. In today's scenario, it has become very popular among people because of its beneficial health benefits. The high composition of nutrients in wheatgrass provides multiple pharmacological and therapeutic qualities, mainly including antioxidant, anti-inflammatory, anti-diabetic, detoxification, and anti-aging effects. Clinical trials have demonstrated its multiple therapeutic capabilities as an antioxidant and anti-inflammatory, especially for chronic inflammation, blood purification, general detoxification, and cleanse of the colon. Moreover, it also promotes skin health and boosts biochemical functions as well. With its numerous health benefits, wheatgrass can be an essential addition to skincare routines, offering a natural solution for healthier, more radiant skin and enhanced overall well-being.
References
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28. Dholi UK. “Phytochemical screening and estimation of the nutritional content of wheatgrass powder and wheatgrass juice.” World J Pharm Res. 2018, 7, 882-896.
29. Singh KG, Sultana SS, Almeida SA, Kadur SA. “ex-vivo studies of the effect of wheatgrass on glucose release and gluconeogenesis using cortisol-induced hepatocytes” International Journal of Pharmaceutical Sciences and Research. 2024, 15, 2296-2304.
30. Tullo A, Abera S. “Review on Nutrient Contents and Health Benefits of Wheatgrass Juice.” International Journal of Smart Agriculture. 2023, 1, 32-39.
31. Roshan K, Rathore KS, Bharkatiya M, Goel PK, Naruka PS, Saurabh SS. “Therapeutic potential of Triticum asetivum Linn. Wheatgrass or Green blood therapy) in the treatment and prevention of chronic and acute diseases: An Overview” Pharma Tutor. 2016, 4, 19-27.
32. Grubisic S, Kristic M, Lisjak M, Miskovic Spoljaric K, Petrovic S, Vila S, Rebekic A. “Effect of wheatgrass juice on nutritional quality of apple, carrot, beet, orange and lemon juice.” Foods. 2022, 11, 445.
33. Lae KZ, Oo HH. “A study on the biochemical properties of Triticum aestivum Linn (wheatgrass).” Universities Research Journal. 2014, 6, 141-159.
34. Rajoria A, Mehta A, Mehta P, Ahirwal L, Shukla S, Bajpai VK. “Evaluation of antiproliferative and hepatoprotective effects of wheat grass (Triticum aestivum).” Acta Biologica Hungarica. 2017, 68, 150-61.
35. Mujoriya R, Bodla RB. “A study on wheat grass and its nutritional value.” Food Science and Quality Management. 2011, 2, 1-8.
36. Kumar NS, Murali M, Nair AM, Nair AS. “Green blood therapy of wheat grass Nature’s finest medicine’-A literature review.” J Pharm Biol Sci. 2016, 11, 57-64.
37. Kaviya M, Balamurali Krishnan B, Sangeetha T, Senthilkumar N, Malaisamy A, Sivasamy M, Poorni L, Pushparaj K, Arun M, Anand AV. “Evaluation of phytoconstituents of Triticum aestivum grass extracts on nutritional attributes, antioxidant, and antimicrobial activities against food pathogens with molecular in silico investigation.” Food Frontiers. 2023, 4, 831-48.
38. Awulachew MT. “The role of wheat in human nutrition and its medicinal value.” Glob Acad J Med Sci. 2020, 2, 50-54.
39. Suriyavathana M, Roopavathi I. “Phytochemical characterization of Triticum Aestivum (wheat grass).” Journal of Pharmacognosy and Phytochemistry. 2016, 5, 283-286.
40. Sareen M, Baghla P, Dhaka P, Mathur E, Sobti P, Khajuria S. “Wheat grass-a wonder herb.” Systematic Reviews in Pharmacy. 2014, 5, 4-5.
41. Marwaha RK, Bansal D, Kaur S, Trehan A. “Wheat Grass Juice Reduces Transfusion Requirement in Patients with Thalassemia Major: A Pilot Study.” Indian Pediatrics. 2004, 41, 716-720.
42. Costa EF, Magalhaes WV, Di Stasi LC. “Recent advances in herbal-derived products with skin anti-aging properties and cosmetic applications.” Molecules. 2022, 27, 7518.
43. Hassan N, Siddique MS. “Wheat Grass (Triticum aestivum L.) Benefits Health in a Pandemic Scenario.” Journal for Research in Applied Sciences and Biotechnology. 2022, 1, 24-39.
44. Mathur S, Mathur R, Kohli GK. “Therapeutic use of wheat grass juice for the treatment of anemia in young women of Ajmer city (Rajasthan, India).” Internat. J. Nutrit. Sci. 2017, 2, 1014.
45. Chauhan M. “A pilot study on wheat grass juice for its phytochemical, nutritional and therapeutic potential on chronic diseases.” International journal of chemical studies. 2014, 2, 27-34.
46. Hudiyati M, Sunarintyas S, Ardhani R, Isnansetyo A. “Therapeutic potential of fucoidan in dentistry: A review.” Journal of Herbmed Pharmacology. 2024, 13, 188-198.
47. Singh N, Verma P, Pandey BR. “Therapeutic potential of organic Triticum aestivum Linn. (Wheat Grass) in prevention and treatment of chronic diseases: An overview.” International Journal of Pharmaceutical Sciences and Drug Research. 2012, 1, 10-14.
48. Rodriguez FC, Gallagher E, Rai DK, Burgess CM. “Nutritional and physiochemical properties of wheatgrass juice and preservation strategies.” Food Chemistry Advances. 2022, 1, 100136.
49. Mutha AS, Shah KU, Kinikar AA, Ghongane BB. “Efficacy and safety of wheat grass in thalassemic children on regular blood transfusion.” Cureus. 2018, 10, 2306
50. Desai TR, Solanki JK, Buch P, Goyal RK. “Triticum aestivum (Wheatgrass) formulation: an alternate treatment for the patients with thalassemia.” Oriental pharmacy and experimental medicine. 2008, 7, 466-476.
2. Rana S, Kamboj JK, Gandhi V. “Living life the natural way–Wheatgrass and Health.” Functional foods in health and disease. 2011, 1, 444-456.
3. Borkar S. “Product development of wheat grass powder and its nutritional analysis.” International journal of multidisciplinary educational research. 2021, 4, 114-116.
4. Ogutu FO, Makori SI, Maringa CW, Lemtukei D, Okiko G, Luvita S. “Wheat grass: A functional food.” Food Science and Quality Management. 2017, 65, 33-38.
5. Ahmed M, Saifullah SB, Khatun AA, Ove TA. “Effectiveness of solvent extraction on phytochemicals and antioxidant activities from fresh and dried wheatgrass.” European Journal of Nutrition & Food Safety. 2021, 13, 1-10.
6. Anand R, Singh P. “The effect of wheat grass juice in type-2 diabetes mellitus.” World Journal of Pharmaceutical Research. 2020, 9, 943-956.
7. Mane SS, Pise VG. “The Health Benefits of Wheatgrass Juice Consumption Nutritional and Physiochemical Properties Benefits”. Easy Chair 2024, 12225.
8. Chowdhury GR, Agarwal S, Sen T, Zaman S, Mitra A. “Wheatgrass: A biogem in the health care spectrum.” Journal of Science, Engineering, Health and Management. 2017, 1, 62-64.
9. Anand R, Singh P. “The wheat grass-a literature review.” World Journal of Pharmaceutical Research. 2023, 12, 1514-1525.
10. Adhikari B, Joshi S. “Preparation and Quality Evaluation of Ready to Serve (RTS) Wheatgrass Juice.” Dristikon: A Multidisciplinary Journal. 2023, 13, 12-28.
11. Balakrishnan S. “Review on: Growing a glass of rich immune booster at your home: Triticum aestivum L. (wheat grass) beneficial effect on health in this pandemic scenario.” International Journal for Research in Applied Sciences and Biotechnology. 2020, 7, 141-145.
12. Pannu JS, Kapoor RK. “The green blood” wheatgrass juice, a health tonic having antibacterial potential.” World Journal of Pharmaceutical Research. 2015, 4, 46-54.
13. GE El-Sahar ES. “Effect of Wheatgrass (Triticum aestivum Linn) Extracts as Source of Antioxidants on some biochemical parameters and Markers of Aging.” International Journal of Family Studies, Food Science and Nutrition Health. 2021, 2, 46-67.
14. Kulkarni SD. et al “Evaluation of the antioxidant activity of wheatgrass (Triticum aestivum L.) as a function of growth under different conditions.” Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives. 2006, 20, 218-227.
15. Sundaresan A, Selvi A, Manonmani HK. “The anti-microbial properties of Triticum aestivum (wheat grass) extract.” International Journal of Biotechnology for Wellness Industries. 2015, 4, 84-91.
16. Eissa HA, Mohamed SS, Hussein AM. “Nutritional value and impact of wheatgrass juice (Green Blood Therapy) on increasing fertility in male albino rats.” Bulletin of the National Research Centre. 2020, 44, 1-11.
17. Nigam V. “Pharmacognostic, phytochemical investigation & pharmacological study of young leaves of Triticum aestivum Linn.” International Journal of Pharmaceutical Sciences. 2019, 5, 16–19.
18. Murthy SR. “Therapeutic role of “Wheatgrass (Triticum aestivum Linn.) in iron deficiency anaemia.” International Journal of Pharmacognosy and Life Science. 2020, 1, 01-04.
19. Ashok SA. “Phytochemical and pharmacological screening of wheatgrass juice (Triticum aestivum L.).” International Journal of Pharmaceutical Sciences Review and Research. 2011, 9, 159-164.
20. Minocha N, Saini S, Pandey P. “Nutritional prospects of wheatgrass (Triticum aestivum) and its effects in treatment and chemoprevention.” Exploration of Medicine. 2022, 3, 432-442.
21. Ghumman A, Singh N, Kaur A. “Chemical, nutritional and phenolic composition of wheatgrass and pulse shoots.” International journal of food science & technology. 2017, 52, 2191-2200.
22. Thakur N, Dhaliwal HS, Sharma V. “Chemical composition, minerals and vitamins analysis of lyophilized wheatgrass juice powder.” International Journal on Emerging Technologies. 2019, 10, 137-144.
23. Karadahin M, Argon ZU. “Green blood: wheatgrass juice”. International Congress on Medicinal and Aromatic Plants Natural and Healthy Life Proceedings Book 2017, 513-527.
24. Beniwal A, Das M, Bhattacharyya P. “Therapeutic uses of wheatgrass juice.” Advances in Plant Science Book Volume V, Bhumi Publishing, Maharashtra, India 2022, 75-98.
25. Choudhary SH, Kaurav HE, Chaudhary GI. “Wheatgrass (Triticum aestivum Linn.): a potential substitute of human blood in traditional system of medicine.” Asian J Pharm Clin Res. 2021, 14, 43-47.
26. Agrawal T, Dewan P, Gomber S, Agarwal R, Sharma S, Kotru M. “Optimum dose of oral folic acid supplementation in transfusion-dependent thalassemia: a randomized controlled trial.” Journal of Tropical Pediatrics. 2022, 68, 1-8.
27. Runjala S, Murthy YL. “Study On the Effect of Wheat Grass Biscuits on Blood Haemoglobin Level for The Treatment of Iron Deficiency Anemia in Adolescent Girls at Welfare Hostel in Vizainagaram District, Andhra Pradesh, India.” Think India Journal. 2019, 22, 57-61.
28. Dholi UK. “Phytochemical screening and estimation of the nutritional content of wheatgrass powder and wheatgrass juice.” World J Pharm Res. 2018, 7, 882-896.
29. Singh KG, Sultana SS, Almeida SA, Kadur SA. “ex-vivo studies of the effect of wheatgrass on glucose release and gluconeogenesis using cortisol-induced hepatocytes” International Journal of Pharmaceutical Sciences and Research. 2024, 15, 2296-2304.
30. Tullo A, Abera S. “Review on Nutrient Contents and Health Benefits of Wheatgrass Juice.” International Journal of Smart Agriculture. 2023, 1, 32-39.
31. Roshan K, Rathore KS, Bharkatiya M, Goel PK, Naruka PS, Saurabh SS. “Therapeutic potential of Triticum asetivum Linn. Wheatgrass or Green blood therapy) in the treatment and prevention of chronic and acute diseases: An Overview” Pharma Tutor. 2016, 4, 19-27.
32. Grubisic S, Kristic M, Lisjak M, Miskovic Spoljaric K, Petrovic S, Vila S, Rebekic A. “Effect of wheatgrass juice on nutritional quality of apple, carrot, beet, orange and lemon juice.” Foods. 2022, 11, 445.
33. Lae KZ, Oo HH. “A study on the biochemical properties of Triticum aestivum Linn (wheatgrass).” Universities Research Journal. 2014, 6, 141-159.
34. Rajoria A, Mehta A, Mehta P, Ahirwal L, Shukla S, Bajpai VK. “Evaluation of antiproliferative and hepatoprotective effects of wheat grass (Triticum aestivum).” Acta Biologica Hungarica. 2017, 68, 150-61.
35. Mujoriya R, Bodla RB. “A study on wheat grass and its nutritional value.” Food Science and Quality Management. 2011, 2, 1-8.
36. Kumar NS, Murali M, Nair AM, Nair AS. “Green blood therapy of wheat grass Nature’s finest medicine’-A literature review.” J Pharm Biol Sci. 2016, 11, 57-64.
37. Kaviya M, Balamurali Krishnan B, Sangeetha T, Senthilkumar N, Malaisamy A, Sivasamy M, Poorni L, Pushparaj K, Arun M, Anand AV. “Evaluation of phytoconstituents of Triticum aestivum grass extracts on nutritional attributes, antioxidant, and antimicrobial activities against food pathogens with molecular in silico investigation.” Food Frontiers. 2023, 4, 831-48.
38. Awulachew MT. “The role of wheat in human nutrition and its medicinal value.” Glob Acad J Med Sci. 2020, 2, 50-54.
39. Suriyavathana M, Roopavathi I. “Phytochemical characterization of Triticum Aestivum (wheat grass).” Journal of Pharmacognosy and Phytochemistry. 2016, 5, 283-286.
40. Sareen M, Baghla P, Dhaka P, Mathur E, Sobti P, Khajuria S. “Wheat grass-a wonder herb.” Systematic Reviews in Pharmacy. 2014, 5, 4-5.
41. Marwaha RK, Bansal D, Kaur S, Trehan A. “Wheat Grass Juice Reduces Transfusion Requirement in Patients with Thalassemia Major: A Pilot Study.” Indian Pediatrics. 2004, 41, 716-720.
42. Costa EF, Magalhaes WV, Di Stasi LC. “Recent advances in herbal-derived products with skin anti-aging properties and cosmetic applications.” Molecules. 2022, 27, 7518.
43. Hassan N, Siddique MS. “Wheat Grass (Triticum aestivum L.) Benefits Health in a Pandemic Scenario.” Journal for Research in Applied Sciences and Biotechnology. 2022, 1, 24-39.
44. Mathur S, Mathur R, Kohli GK. “Therapeutic use of wheat grass juice for the treatment of anemia in young women of Ajmer city (Rajasthan, India).” Internat. J. Nutrit. Sci. 2017, 2, 1014.
45. Chauhan M. “A pilot study on wheat grass juice for its phytochemical, nutritional and therapeutic potential on chronic diseases.” International journal of chemical studies. 2014, 2, 27-34.
46. Hudiyati M, Sunarintyas S, Ardhani R, Isnansetyo A. “Therapeutic potential of fucoidan in dentistry: A review.” Journal of Herbmed Pharmacology. 2024, 13, 188-198.
47. Singh N, Verma P, Pandey BR. “Therapeutic potential of organic Triticum aestivum Linn. (Wheat Grass) in prevention and treatment of chronic diseases: An overview.” International Journal of Pharmaceutical Sciences and Drug Research. 2012, 1, 10-14.
48. Rodriguez FC, Gallagher E, Rai DK, Burgess CM. “Nutritional and physiochemical properties of wheatgrass juice and preservation strategies.” Food Chemistry Advances. 2022, 1, 100136.
49. Mutha AS, Shah KU, Kinikar AA, Ghongane BB. “Efficacy and safety of wheat grass in thalassemic children on regular blood transfusion.” Cureus. 2018, 10, 2306
50. Desai TR, Solanki JK, Buch P, Goyal RK. “Triticum aestivum (Wheatgrass) formulation: an alternate treatment for the patients with thalassemia.” Oriental pharmacy and experimental medicine. 2008, 7, 466-476.
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Dec 12, 2024
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How to Cite
Atul Mer, Ms. Krupa Vyas, & Dr. Pragnesh Patani. (2024). WHEATGRASS: A COMPREHENSIVE REVIEW ON ITS THERAPEUTIC POTENTIAL. Journal of Population Therapeutics and Clinical Pharmacology, 31(11), 1252-1260. https://doi.org/10.53555/1rmwrf75
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Author Biographies
Atul Mer
Student, Khyati College of Pharmacy, Palodia, Ahmedabad.
Ms. Krupa Vyas
Assistant Professor, Khyati College of Pharmacy, Palodia, Ahmedabad
Dr. Pragnesh Patani
Principal and Professor, Khyati College of Pharmacy, Palodia, Ahmedabad
How to Cite
Atul Mer, Ms. Krupa Vyas, & Dr. Pragnesh Patani. (2024). WHEATGRASS: A COMPREHENSIVE REVIEW ON ITS THERAPEUTIC POTENTIAL. Journal of Population Therapeutics and Clinical Pharmacology, 31(11), 1252-1260. https://doi.org/10.53555/1rmwrf75