MANAGING ECZEMA WITH OENOTHERA BIENNIS OIL: BENEFITS AND APPLICATION
Main Article Content
Keywords
Eczema, Atopic dermatitis, Oenothera biennis oil, Gamma-linolenic acid, Essential fatty acids, Anti-inflammatory properties, Skin barrier function
Abstract
Eczema is a chronic inflammatory skin condition, presents with red, itchy, and dry patches that can lead to severe discomfort and secondary infections. This disorder, often associated with atopic dermatitis, is linked to genetic, environmental, and immunological factors. Oenothera biennis oil, which is derived from seeds, has potential benefits in managing eczema. It contain gamma-linolenic acid and other essential fatty acids, which have anti-inflammatory properties and supports skin barrier function. The special benefits of oenothera biennis oil, such as to improve skin moisture and reduce inflammation, both can help with common eczema symptoms.
References
1. Bhowmik D, Chiranjib B, Sampathkumar KP. Recent trends in treatment and prevention of eczema. Journal of Global Pharma Technology. 2010;2:12-21.
2. Senapati S, Banerjee S, Gangopadhyay DN. Evening primrose oil is effective in atopic dermatitis: a randomized placebo-controlled trial. Indian Journal of Dermatology, Venereology and leprology. 2008;74:447-452.
3. Gangopadhyay DN, Naskar B, Roy AK. Atopic dermatitis and ABO blood group. Indian Journal Dermatol. 2006;51:33-35.
4. Kirubakaran JJ, Surekha KL, Manasa S, Chakra AN, Satyanarayana KV, Palivela H, Kumar P, Dhanaraju MD. Evaluation and management of atopic dermatitis. Indian Journal of Pharmacy Practice. 2020;13:145-150.
5. Egawa G, Weninger W. Pathogenesis of atopic dermatitis: a short review. Cogent Biology. 2015;1:1-10.
6. Bindu V, Ahmed N, Najeeba R. Atopic dermatitis in children: A clinico epidemiological study and the role of dietary restrictions in disease severity. International Journal of Research. 2017;3:168-174.
7. Lee JH, Son SW, Cho SH. A comprehensive review of the treatment of atopic eczema. Allergy, Asthma & Immunology Research. 2016;8:181-90.
8. Williams HC. Atopic dermatitis. N Engl J Med. 2005; 352:2314-2324.
9. Kim J, Kim BE, Leung DY. Pathophysiology of atopic dermatitis: Clinical implications. In Allergy and asthma proceedings. 2019;40:84-92.
10. Thyssen JP, Kezic S. Causes of epidermal filaggrin reduction and their role in the pathogenesis of atopic dermatitis. Journal of Allergy and Clinical Immunology. 2014;134:792-799.
11. Michail S. The role of probiotics in allergic diseases. Allergy, Asthma & Clinical Immunology. 2009;5:1-7.
12. Bieber T. Atopic dermatitis. Ann Dermatol. 2010;22:125-137.
13. Pyun BY. Natural history and risk factors of atopic dermatitis in children. Allergy, Asthma & Immunology Research. 2015;7:101-105.
14. Palmer CN, Irvine AD, Terron-Kwiatkowski A, Zhao Y, Liao H, Lee SP, Goudie DR, Sandilands A, Campbell LE, Smith FJ, O'Regan GM. Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis. Nature Genetics. 2006;38:441-446
15. Van der Poel LA, Warner JO. Paediatric allergy in review. Paediatrics and Child Health. 2012;22:259-63.
16. Edard V, Natalie S, Mojakgomo H. M. A review of the risk factors and clinical presentation of childhood atopic eczema at primary healthcare level. Current Allergy and Clinical Immunology. 2016;29:24-29.
17. Von Mutius E. Gene-environment interactions in asthma. Journal of Allergy and Clinical Immunology. 2009;123:3-11.
18. Lee JH, Lee HS, Park MR, Lee SW, Kim EH, Cho JB, Kim J, Han Y, Jung K, Cheong HK, Lee SI. Relationship between indoor air pollutant levels and residential environment in children with atopic dermatitis. Allergy, Asthma & Immunology Research. 2014;6:517-524.
19. De Benedetto A, Kubo A, Beck LA. Skin barrier disruption: a requirement for allergen sensitization?. Journal of Investigative Dermatology. 2012;132:949-963.
20. Proksch E, Fölster-Holst R, Jensen JM. Skin barrier function, epidermal proliferation and differentiation in eczema. Journal of dermatological science. 2006;43:159-169.
21. Jordaan HF, Visser WI. The diagnosis and management of atopic dermatitis. South African Family Practice. 2009;51:368-374.
22. Sinclair W, Aboobaker J, Jordaan F, Modi D, Todd G. Management of atopic dermatitis in adolescents and adults in South Africa. South African Medical Journal. 2008;98:303-320.
23. Rawat N, Moharana P, Roushan R. Ayurvedic management of Vicharchika (Eczema)-A case report. International Journal of Basic and Applied Research. 2018;8:1365-1370
24. Terrie YC. Treatment and management of dermatitis: pharmacists can help patients self-treat cases of atopic and contact dermatitis. Pharmacy Times. 2013;79:22-24.
25. Cassler NM, Burris AM, Nguyen JC. Asteatotic eczema in hypoesthetic skin: a case series. JAMA Dermatology. 2014;150:1088-1090.
26. Bonamonte D, Filoni A, Gullo G, Vestita M. Nummular contact eczema: presentation of a pediatric case. The Open Dermatology Journal. 2019;13:23-26.
27. Abreu-Velez AM, Pinto Jr FJ, Howard MS. Dyshidrotic eczema: relevance to the immune response in situ. North American Journal of Medical Sciences. 2009;1:117-120.
28. Eberting CL. Irritant contact dermatitis: mechanisms to repair. J Clin Exp Dermatol Res. 2014;5: 2-8.
29. Ijaz N, Fitzgerald D. Seborrhoeic dermatitis. British journal of hospital medicine. 2017;78:88-91.
30. Sundaresan S, Migden MR, Silapunt S. Stasis dermatitis: pathophysiology, evaluation, and management. American Journal of Clinical Dermatology. 2017;18:383-390.
31. Ghatas YA, Mohamed YF. Influence of some phosphorus sources and biofertilizers (EM and phosphorein) on vegetative growth, fixed oil productivity and chemical constituents of Oenothera biennis L. plant. Scientific Journal of Flowers and Ornamental Plants. 2020;7:247-68.
32. Waner WL, Hoch PC, Raven PH. Revised classification of the Onagraceae. Systematic Botany Monographs. 2007;83:1-240
33. Thakur U, Dutt B, Sharma SS, Sharma KR, Thakur N. Evening Primrose (Oenothera biennis L.): Morphology and Reproductive Biology. Int. J. Curr. Microbiol. Appl. Sci. 2019;8:1400-1409.
34. Paciorek-Sadowska J, Borowicz M, Isbrandt M. Effect of evening primrose (Oenothera biennis) oil cake on the properties of polyurethane/polyisocyanurate bio-composites. International Journal of Molecular Sciences. 2021;22:8950-8971.
35. Timoszuk M, Bielawska K, Skrzydlewska E. Evening primrose (Oenothera biennis) biological activity dependent on chemical composition. Antioxidants. 2018;7:108-118.
36. Mahwish A, Bahisht R, Shahid B, Maria A, Sadia B, Asra A, Zuha S, Fatima R, Azka AS. Evening primrose (oenothera biennis) ‘A miracle gift of nature’ for females. Innovative scientific information & services network. 2021;18:3280-3292.
37. Munir R, Semmar N, Farman M, Ahmad NS. An updated review on pharmacological activities and phytochemical constituents of evening primrose (genus Oenothera). Asian Pacific Journal of Tropical Biomedicine. 2017;7:1046-1054.
38. Farag MA, Reda A, Nabil M, Elimam DM, Zayed A. Evening primrose oil: A comprehensive review of its bioactives, extraction, analysis, oil quality, therapeutic merits, and safety. Food & Function. 2023;14:8049-8070.
39. Chung BY, Park SY, Jung MJ, Kim HO, Park CW. Effect of evening primrose oil on Korean patients with mild atopic dermatitis: a randomized, double-blinded, placebo-controlled clinical study. Annals of Dermatology. 2018;30:409-416.
40. Simon D, Eng PA, Borelli S, Kägi R, Zimmermann C, Zahner C, Drewe J, Hess L, Ferrari G, Lautenschlager S, Wüthrich B. Gamma-linolenic acid levels correlate with clinical efficacy of evening primrose oil in patients with atopic dermatitis. Advances in Therapy. 2014;31:180-188.
41. Kawamura A, Ooyama K, Kojima K, Kachi H, Abe T, Amano K, Aoyama T. Dietary supplementation of gamma-linolenic acid improves skin parameters in subjects with dry skin and mild atopic dermatitis. Journal of Oleo Science. 2011;60:597-60
2. Senapati S, Banerjee S, Gangopadhyay DN. Evening primrose oil is effective in atopic dermatitis: a randomized placebo-controlled trial. Indian Journal of Dermatology, Venereology and leprology. 2008;74:447-452.
3. Gangopadhyay DN, Naskar B, Roy AK. Atopic dermatitis and ABO blood group. Indian Journal Dermatol. 2006;51:33-35.
4. Kirubakaran JJ, Surekha KL, Manasa S, Chakra AN, Satyanarayana KV, Palivela H, Kumar P, Dhanaraju MD. Evaluation and management of atopic dermatitis. Indian Journal of Pharmacy Practice. 2020;13:145-150.
5. Egawa G, Weninger W. Pathogenesis of atopic dermatitis: a short review. Cogent Biology. 2015;1:1-10.
6. Bindu V, Ahmed N, Najeeba R. Atopic dermatitis in children: A clinico epidemiological study and the role of dietary restrictions in disease severity. International Journal of Research. 2017;3:168-174.
7. Lee JH, Son SW, Cho SH. A comprehensive review of the treatment of atopic eczema. Allergy, Asthma & Immunology Research. 2016;8:181-90.
8. Williams HC. Atopic dermatitis. N Engl J Med. 2005; 352:2314-2324.
9. Kim J, Kim BE, Leung DY. Pathophysiology of atopic dermatitis: Clinical implications. In Allergy and asthma proceedings. 2019;40:84-92.
10. Thyssen JP, Kezic S. Causes of epidermal filaggrin reduction and their role in the pathogenesis of atopic dermatitis. Journal of Allergy and Clinical Immunology. 2014;134:792-799.
11. Michail S. The role of probiotics in allergic diseases. Allergy, Asthma & Clinical Immunology. 2009;5:1-7.
12. Bieber T. Atopic dermatitis. Ann Dermatol. 2010;22:125-137.
13. Pyun BY. Natural history and risk factors of atopic dermatitis in children. Allergy, Asthma & Immunology Research. 2015;7:101-105.
14. Palmer CN, Irvine AD, Terron-Kwiatkowski A, Zhao Y, Liao H, Lee SP, Goudie DR, Sandilands A, Campbell LE, Smith FJ, O'Regan GM. Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis. Nature Genetics. 2006;38:441-446
15. Van der Poel LA, Warner JO. Paediatric allergy in review. Paediatrics and Child Health. 2012;22:259-63.
16. Edard V, Natalie S, Mojakgomo H. M. A review of the risk factors and clinical presentation of childhood atopic eczema at primary healthcare level. Current Allergy and Clinical Immunology. 2016;29:24-29.
17. Von Mutius E. Gene-environment interactions in asthma. Journal of Allergy and Clinical Immunology. 2009;123:3-11.
18. Lee JH, Lee HS, Park MR, Lee SW, Kim EH, Cho JB, Kim J, Han Y, Jung K, Cheong HK, Lee SI. Relationship between indoor air pollutant levels and residential environment in children with atopic dermatitis. Allergy, Asthma & Immunology Research. 2014;6:517-524.
19. De Benedetto A, Kubo A, Beck LA. Skin barrier disruption: a requirement for allergen sensitization?. Journal of Investigative Dermatology. 2012;132:949-963.
20. Proksch E, Fölster-Holst R, Jensen JM. Skin barrier function, epidermal proliferation and differentiation in eczema. Journal of dermatological science. 2006;43:159-169.
21. Jordaan HF, Visser WI. The diagnosis and management of atopic dermatitis. South African Family Practice. 2009;51:368-374.
22. Sinclair W, Aboobaker J, Jordaan F, Modi D, Todd G. Management of atopic dermatitis in adolescents and adults in South Africa. South African Medical Journal. 2008;98:303-320.
23. Rawat N, Moharana P, Roushan R. Ayurvedic management of Vicharchika (Eczema)-A case report. International Journal of Basic and Applied Research. 2018;8:1365-1370
24. Terrie YC. Treatment and management of dermatitis: pharmacists can help patients self-treat cases of atopic and contact dermatitis. Pharmacy Times. 2013;79:22-24.
25. Cassler NM, Burris AM, Nguyen JC. Asteatotic eczema in hypoesthetic skin: a case series. JAMA Dermatology. 2014;150:1088-1090.
26. Bonamonte D, Filoni A, Gullo G, Vestita M. Nummular contact eczema: presentation of a pediatric case. The Open Dermatology Journal. 2019;13:23-26.
27. Abreu-Velez AM, Pinto Jr FJ, Howard MS. Dyshidrotic eczema: relevance to the immune response in situ. North American Journal of Medical Sciences. 2009;1:117-120.
28. Eberting CL. Irritant contact dermatitis: mechanisms to repair. J Clin Exp Dermatol Res. 2014;5: 2-8.
29. Ijaz N, Fitzgerald D. Seborrhoeic dermatitis. British journal of hospital medicine. 2017;78:88-91.
30. Sundaresan S, Migden MR, Silapunt S. Stasis dermatitis: pathophysiology, evaluation, and management. American Journal of Clinical Dermatology. 2017;18:383-390.
31. Ghatas YA, Mohamed YF. Influence of some phosphorus sources and biofertilizers (EM and phosphorein) on vegetative growth, fixed oil productivity and chemical constituents of Oenothera biennis L. plant. Scientific Journal of Flowers and Ornamental Plants. 2020;7:247-68.
32. Waner WL, Hoch PC, Raven PH. Revised classification of the Onagraceae. Systematic Botany Monographs. 2007;83:1-240
33. Thakur U, Dutt B, Sharma SS, Sharma KR, Thakur N. Evening Primrose (Oenothera biennis L.): Morphology and Reproductive Biology. Int. J. Curr. Microbiol. Appl. Sci. 2019;8:1400-1409.
34. Paciorek-Sadowska J, Borowicz M, Isbrandt M. Effect of evening primrose (Oenothera biennis) oil cake on the properties of polyurethane/polyisocyanurate bio-composites. International Journal of Molecular Sciences. 2021;22:8950-8971.
35. Timoszuk M, Bielawska K, Skrzydlewska E. Evening primrose (Oenothera biennis) biological activity dependent on chemical composition. Antioxidants. 2018;7:108-118.
36. Mahwish A, Bahisht R, Shahid B, Maria A, Sadia B, Asra A, Zuha S, Fatima R, Azka AS. Evening primrose (oenothera biennis) ‘A miracle gift of nature’ for females. Innovative scientific information & services network. 2021;18:3280-3292.
37. Munir R, Semmar N, Farman M, Ahmad NS. An updated review on pharmacological activities and phytochemical constituents of evening primrose (genus Oenothera). Asian Pacific Journal of Tropical Biomedicine. 2017;7:1046-1054.
38. Farag MA, Reda A, Nabil M, Elimam DM, Zayed A. Evening primrose oil: A comprehensive review of its bioactives, extraction, analysis, oil quality, therapeutic merits, and safety. Food & Function. 2023;14:8049-8070.
39. Chung BY, Park SY, Jung MJ, Kim HO, Park CW. Effect of evening primrose oil on Korean patients with mild atopic dermatitis: a randomized, double-blinded, placebo-controlled clinical study. Annals of Dermatology. 2018;30:409-416.
40. Simon D, Eng PA, Borelli S, Kägi R, Zimmermann C, Zahner C, Drewe J, Hess L, Ferrari G, Lautenschlager S, Wüthrich B. Gamma-linolenic acid levels correlate with clinical efficacy of evening primrose oil in patients with atopic dermatitis. Advances in Therapy. 2014;31:180-188.
41. Kawamura A, Ooyama K, Kojima K, Kachi H, Abe T, Amano K, Aoyama T. Dietary supplementation of gamma-linolenic acid improves skin parameters in subjects with dry skin and mild atopic dermatitis. Journal of Oleo Science. 2011;60:597-60
Article Sidebar
Published
Dec 11, 2024
Article Details
How to Cite
Riya Patel, Ms. Purvi Ramanuj, & Dr. Pragnesh Patani. (2024). MANAGING ECZEMA WITH OENOTHERA BIENNIS OIL: BENEFITS AND APPLICATION. Journal of Population Therapeutics and Clinical Pharmacology, 31(11), 1009-1016. https://doi.org/10.53555/zbrcb807
Section
Articles
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All articles published in JPTCP are licensed under Copyright Creative Commons Attribution-NonCommercial 4.0 International License.
Author Biographies
Riya Patel
Student, Khyati College of Pharmacy, Palodia, Ahmedabad
Ms. Purvi Ramanuj
Associate Professor, Khyati College of Pharmacy, Palodia, Ahmedabad
Dr. Pragnesh Patani
Principal, Khyati College of Pharmacy, Palodia, Ahmedabad
How to Cite
Riya Patel, Ms. Purvi Ramanuj, & Dr. Pragnesh Patani. (2024). MANAGING ECZEMA WITH OENOTHERA BIENNIS OIL: BENEFITS AND APPLICATION. Journal of Population Therapeutics and Clinical Pharmacology, 31(11), 1009-1016. https://doi.org/10.53555/zbrcb807