FINDING AND ROLE OF HEPATITIS C VIRUS IN THE PATHOGENESIS OF HODGKIN LYMPHOMA PATIENTS: A STUDY AT COMBINED MILITARY HOSPITAL PESHAWAR
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Keywords
HCV, Hodgkin Lymphoma, pathogenesis, prevalence
Abstract
Background: Hodgkin Lymphoma (HL) is a cancer of the lymphatic system; however, its cause is still unknown to date. Newer studies indicate that Hepatitis C Virus (HCV) may play a role in HL development.
Objectives: The study aims are as follows: To establish the incidence of HCV in HL patients and examine its involvement in HL advancement.
Study design: A cross-sectional study.
Place and duration of study. Combined Military Hospital Peshawar from 05-Jan 2023 to 05-Jan 2024.
Methods: Consequently, this study was cross-sectional, for which we recruited 200 patients with HL at CMH Peshawar. Information on HCV status included self-reports from patients’ medical records and blood tests. Data analysis was done using SPSS 24. 0 to analyze the HCV and HL relationship.
Results: Among the 200 patients (mean age: The study participants’ mean age was 45 years with a standard deviation of 12 years; 20% of the participants were HCV positive. Results of the analysis of data revealed that there was a moderate relationship between HCV infection and HL at the P = 0. 03 level of significance.
Conclusion: Based on this study, HCV infection has a significant positive relationship with HL and may therefore be involved in HL development. Preventive measures include the recommendation of routine hepatitis C virus screening in HL patients to enhance identification and treatment.
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Sayyeda Aisha Bahar
Female Medical Officer, DHQ, Mishti Mela, Orakzai, KPK
Aqsa Amjad
TMO Medicine Combined Military Hospital Peshawar, KPK
Sana Arshad
TMO Medicine Khyber Teaching Hospital, Peshawar, KPK
Alina
TMO Medicine Khyber Teaching Hospital, Peshawar, KPK
Fazal Rabi
Medical Specialist DHQ, Mishti Mela, Orakzai, KPK
Kamran Saeed
TMO Medicine Ayub Teaching Hospital, Abbottabad, KPK
Junaid Farman
TMO Orthopedics Ayub Teaching Hospital, Abbottabad, KPK