ROLE OF FOLIC ACID AND POTASSIUM SUPPLEMENTATION AGAINST LOSS OF BONE MINERAL DENSITY (BMD) IN POSTMENOPAUSAL OSTEOPOROTIC WOMEN: A RANDOMIZED CONTROL TRIAL
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Keywords
Bone resorption, Bone Mineral Density, Folic acid, Potassium, Postmenopausal Osteoporosis
Abstract
Osteoporosis is a disorder in which bones become brittle and risk of fractures increases and is also becoming common day by day. In US, almost 10 million women and men are affected by this disease. Previously, among all nutrients most of the attention was given to calcium and vitamin D for treating bone disorders but now latest studies suggest that other nutrients such as Folic acid, vitamin B12 and Potassium are also beneficial for bones in addition to vitamin D and calcium. The objective of this study was to evaluate the collective role of Folic acid and Potassium supplementation against loss of Bone Mineral Density in Postmenopausal Osteoporotic women. This study was conducted on postmenopausal osteoporotic women of age 35 to 55 years at Jinnah Hospital, Lahore. The duration of this study was 3 months and study design was Randomized Control trial. The sample size 60 was divided in to two groups. Pre and post testing was done. Group A was control group which did not receive any supplementation while group B was intervention group and received folic acid and potassium supplementation. Results showed positive outcomes and concluded that both folic acid and potassium supplementation have significant effect (p<0.05) as they both increase bone anabolism, lower bone resorption, decrease bone stress and fatigue, while value for BMD remained same.
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Jannat Gull Khan
Department of Allied Health Sciences, Human Nutrition and Dietetics, Riphah International University, Lahore, Pakistan
Muhammad Imran Hussain
Assistant Professor Department of Human Nutrition and Dietetics Riphah International University, Lahore
Gullnoor Khan
Department of Allied Health Sciences, Human Nutrition and Dietetics, Riphah International University, Lahore, Pakistan
Sobia Ikram Sheikh
University of Lahore, Defence Road Campus, Lahore, Pakistan
Tasbiha Irfan
Department of Allied Health Sciences, Human Nutrition and Dietetics, Riphah International University, Lahore, Pakistan
Shiza Maryem
Department of Allied Health Sciences, Human Nutrition and Dietetics, Riphah International University, Lahore, Pakistan
Hina Mushtaq
Department of Allied Health Sciences, Human Nutrition and Dietetics, Riphah International University, Lahore, Pakistan
Eman Shakeel
Department of Allied Health Sciences, Human Nutrition and Dietetics, Riphah International University, Lahore, Pakistan
Komal Rahid
Department of Allied Health Sciences, Human Nutrition and Dietetics, Riphah International University, Lahore, Pakistan
Huba Khalid
Department of Allied Health Sciences, Human Nutrition and Dietetics, Riphah International University, Lahore, Pakistan