COMPARATIVE EFFICACY OF PROPHYLACTIC EPHEDRINE AND PRN EPHEDRINE DURING SPINAL ANESTHESIA FOR CAESARIAN SECTIONS
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Keywords
Prophylactic ephedrine, prn ephedrine, Caesarian sections, Hypotension
Abstract
Background: Hypotension in patients who receive subarachnoid block (SAB) is a potentially serious issue, which is known to lead to significant morbidity if not managed effectively and urgently. In obstetric applications, profound hypotension can potentially lead to serious hypoxia and hypovolemia in the mother and the fetus.
Objective: To determine comparative efficacy of prophylactic ephedrine and prn ephedrine during spinal anesthesia for caesarian sections
Methodology: This comparative study was carried out at the Anaesthesia Department Khyber Teaching Hospital for duration of six months from January 2022 to June 2022. A total of 100 patients were recruited who were scheduled to receive spinal anesthesia for C-section. The patients were categorized into two groups (A and B) 50 patients each. In patients of Group A, ephedrine was used to treat hypotension when indicated, while in Group B, patients received prophylactic ephedrine soon after the subarachnoid block. Hemodynamic changes were recorded and the data was analyzed statistically by using SPSS version 21.
Results: In Group A, the blood pressure dropped in 33 (66 % patients while in group B, hypotension was observed in 9 (18%). This difference was statistically significant (p<0.001).
Conclusion: Our study concludes that prophylactic ephedrine is better than prn ephedrine in prevention of hypotension in patients receiving spinal analgesia for C-Section.
References
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Muhammad Javed khan
Assistant professor Anaesthesia Department Khyber Teaching Hospital Peshawar
Saira khan
Fcps anesthesia trainee Khyber teaching hospital Peshawar
Rumman Khan
Assistant Professor Hepatobiliary surgery Surgical-A Unit Hayatabad Medical complex Peshawar