FREQUENCY OF VITAMIN D DEFICIENCY IN WOMEN WITH PRE-ECLAMPSIA

Main Article Content

Laila Wajid
Afshan Jehan Zeb
Sana Khan

Keywords

Pre-eclampsia, hypertensive disorders of pregnancy, body mass index, vitamin D deficiency

Abstract

Introduction: Preeclampsia (PE) is a multisystem disorder of pregnancy classically characterized by hypertension with significant proteinuria after 20 weeks’ gestation. Inadequate plasma 25(OH)-vitamin D concentration during early pregnancy seems to be associated with more pronounced changes in total cholesterol and low-density lipoprotein cholesterol throughout gestation, and with an increased risk of developing hypertensive disorders.


Objective: To determine the frequency of vitamin D deficiency in women with pre eclampsia


Duration of Study: 11th June 2020 to 11th December, 2020.


Setting: Department of Gynecology and Obstetrics, Hayatabad Medical Complex, Peshawar.


Study Design: Cross sectional study


Materials and Methods: A total of 135 cases presenting with PE were selected in a consecutive manner and checked for vitamin D levels.


Results: The mean age and standard deviation of the sample was 28.7 + 4.7 years.


The mean parity was 1.3 + 1.2 and mean BMI of the study sample was 26.3 + 3.5kg/m2. The mean period of gestation was 32.4 + 2.5 weeks. The mean Vitamin D level was 18 + 8.7mg/ml and vitamin D deficiency was recorded in 62.2% of women.


Conclusion: Vitamin D deficiency is a common problem in our local population with PE and is no significantly associated with age, BMI or period of gestation. More studies are required to develop association of vitamin D with PE after adjusting for factors which can aggravate vitamin D deficiency in PE patients.

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