FREQUENCY OF GESTATIONAL TROPHOBLASTIC DISEASE IN FIRST TRIMESTER MISCARRIAGES
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Keywords
gestational trophoblastic disease,, first trimester, miscarriages
Abstract
Introduction: Gestational trophoblastic disease (GTD) is a group of disorders that range from the premalignant condition of complete and partial molar pregnancies to the malignant conditions of invasive mole, choriocarcinoma, and the extremely rare placental site trophoblastic tumour (PSTT) and epithelioid trophoblastic tumour (ETT).
Objective: To determine the frequency of gestational trophoblastic disease in first trimester miscarriages
Setting: Department of Obstetrics and Gynaecology HMC, Peshawar.
Study Design: Cross-sectional study
Duration of Study: Six months from 30th August 2021 to 30th February 2022.
Material and Methods: All women were subjected to detailed history and clinical examination followed by relevant investigations as per antenatal protocols. Laboratory investigations were included CBC, histopathology and beta HCG. Women who failed to maintain follow up were dropped from the study. All women were managed as per RCOG guidelines
Results: Our study shows that mean age was 27 years with a standard deviation ± 5.92. 113(69%) patients were primi gravida while 51(31%) patients were multi gravida. 108(66%) patients were primi para while 56(34%) patients were multi para. 10(6%) patients had gestational trophoblastic disease while 154(94%) patients didn’t have gestational trophoblastic disease.
Conclusion: Our study concluded that the frequency of gestational trophoblastic disease was 6% in first trimester miscarriages
References
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Sana Khan
Medical Officer Obs and Gynae Unit, Women and Children Hospital, Rajjar Charsadda - Pakistan
Laila Wajid
Medical Officer Obs and Gynae Unit, District Headquarter Hospital, Landikotal - Pakistan
Afshan Jehan Zeb
Medical Officer Obs and Gynae Unit Cat D Hospital, Gara Tajik, Kochian Peshawar - Pakistan