STUDY OF THE CLINICAL PROFILE OF PATIENTS WITH INTRAUTERINE DEATH AND MATERNAL OUTCOMES

Main Article Content

Dr. Anupama Ashvinikumar Deshmukh
Dr. Ashvinikumar Deshmukh
Dr. Soniya Wadekar
Dr. Jyoti Upadhyay
Dr. Bhairavi Deshmukh
Dr. Vijay Patil

Keywords

Intrauterine fetal death, placental abruption, pre-eclampsia, pregnancy outcome, risk factors

Abstract

Background: Intrauterine fetal death (IUFD) significantly impacts mothers and families, with various factors contributing to its occurrence, including maternal health conditions and complications during pregnancy. Improved antenatal care and timely interventions can reduce risks, but many cases remain unexplained. This study aims to analyze the clinical profiles of IUFD patients and their maternal outcomes to enhance prevention and management strategies.
Methodology: This systematic review adheres to PRISMA guidelines and includes a thorough search of major electronic databases. It examines various studies focusing on the clinical profiles of patients with intrauterine death (IUD) and their maternal outcomes, highlighting demographics, risk factors, and complications. Bias risk assessment was conducted using established methods to ensure the reliability of the findings regarding the impact of IUD on maternal health.
Results: This review examined 10 studies on intrauterine fetal death (IUFD), covering 3,437 cases, mainly involving women aged 26-30. IUFD presents significant emotional and physical challenges for mothers and families. Key risk factors include maternal age and health conditions like hypertension and diabetes. While improved antenatal care can reduce risks, many cases remain unexplained, highlighting the need for further research. The study aims to analyze the clinical profiles of IUFD patients and their maternal outcomes to enhance prevention and management strategies.
Conclusion: The review highlights that maternal health issues, particularly hypertension and diabetes, significantly contribute to IUD. Regular antenatal care is crucial for early detection and management. Many cases remain unexplained, emphasizing the need for further research. Improved maternal healthcare can reduce IUD rates and enhance outcomes.

Abstract 20 | pdf Downloads 2

References

1. Heazell AEP, Siassakos D, Blencowe H, et al. Stillbirths: economic and psychosocial consequences. Lancet. 2016;387(10018):604-616.
2. https://www.cerebralpalsyguide.com/birth-injury/intrauterine-fetal-demise/#:~:text=Intrauterine%20fetal%20demise%20(IUFD)%20is,the%2020th%20week%20of%20pregnancy.
3. Maslovich MM, Burke LM. Intrauterine Fetal Demise. [Updated 2022 Oct 31]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK557533/
4. Shakeel A, Kamal A, Ijaz M, Siddiqa M, Tesema GA, Abushal T. Trends and risk factors of stillbirth among women of reproductive age in Pakistan: A multivariate decomposition analysis. Front Public Health. 2023;11:1050136.
5. Dandona R, George S, Majumder M, Akbar M, Kumar GA. Stillbirth undercount in the sample registration system and national family health survey, India. Bull World Health Organ. 2023;101(3):191-201.
6. Fasoulakis Z, Koutras A, Antsaklis P, et al. Intrauterine Growth Restriction Due to Gestational Diabetes: From Pathophysiology to Diagnosis and Management. Medicina (Kaunas). 2023;59(6):1139.
7. Jovanovic I, Ivanovic K, Kostic S, Tadic J, Dugalic S, Petronijevic M, Gojnic M, Petronijevic M, Vrzic-Petronijevic S. Intrauterine Fetal Death in Term Pregnancy—A Single Tertiary Clinic Study. Life. 2023; 13(12):2320.
8. Wada Y, Takahashi H, Sasabuchi Y, et al. Maternal outcomes of placental abruption with intrauterine fetal death and delivery routes: A nationwide observational study. Acta Obstet Gynecol Scand. 2023;102(6):708-715.
9. Mahato RD, Singh A, Shrestha BM, Joshi M, Singh S, Pradhan T. Risk Factors associated with Intrauterine Fetal Death at Birat Medical College Teaching Hospital. Janaki Medical College Journal of Medical Science. 2023;11(1):74-81.
10. Thakur SK, Dangal G. Factors Associated with Intrauterine Fetal Death at Paropakar Maternity Women’s Hospital. Kathmandu Univ Med J. 2022; 79(3):260-3.
11. Monasta L, Giangreco M, Ancona E, Barbone F, Bet E, Boschian-Bailo P, Cacciaguerra G, Cagnacci A, Canton M, Casarotto M, Comar M. Retrospective study 2005–2015 of all cases of fetal death occurred at≥ 23 gestational weeks, in Friuli Venezia Giulia, Italy. BMC Pregnancy and Childbirth. 2020;20:1-0.
12. Malik A, Begum T, Noor S. Study on Etiology and Maternal Complications of Intrauterine Fetal Death. Chatt Maa Shi Hosp Med Coll J [Internet]. 2019;18(1):23-6
13. Thaker RV, Munshi KS, Patel VA, Vasava DC, Makwana NM. Study of feto-maternal outcome in patients with intra uterine fetal death. Int J Reprod Contracept Obstet Gynecol 2018;7:4587-91.
14. BishnoiBL, Jakhar R, Khokhar S.Intrauterine fetal death cases at tertiary center.J.Evid.BasedMed.Healthc.2018;5(5),461-464.
15. Katti K, Anupama Rani V, Umashankar Km, Dharmavijaya Mn, Clinical study of intra uterine fetal death. Indian J Obstet Gynecol Res 2017;4(4):404-406
16. Sharma S, Sidhu H, Kaur S. Analytical study of intrauterine fetal death cases and associated maternal conditions. Int J Appl Basic Med Res. 2016;6(1):11-13.
17. Man J, Hutchinson JC, Heazell AE, Ashworth M, Levine S, Sebire NJ. Stillbirth and intrauterine fetal death: factors affecting determination of cause of death at autopsy. Ultrasound in Obstetrics & Gynecology. 2016;48(5):566-73.
18. Tantengco OA, Diwa MH, Millagrosa PM, Velayo CL. Epidemiology and placental pathology of intrauterine fetal demise in a tertiary hospital in the Philippines. European Journal of Obstetrics & Gynecology and Reproductive Biology: X. 2024;23:100338.
19. Singh N, Pandey K, Gupta N, Arya AK, Pratap C, Naik R. A retrospective study of 296 cases of intra uterine fetal deaths at a tertiary care centre. Int J Reprod Contracept obstet Gynecol. 2013; 2:141-6.
20. Shrestha SR, Yadav BK. Risk factors associated with still births. JNMA J Nepal Med Assoc. 2010;49(177):84-87

Most read articles by the same author(s)