UNLOCKING THE THERAPEUTIC POTENTIAL OF LEPIDIUM MEYENNI
Main Article Content
Keywords
Menstrual Problems, Maca herb, Ginseng herb
Abstract
Lepidium meyenni walp, often known as common maca or peruvian ginseng, is a herbal medicine belongs to the Brassicaceae family. This plant is native to the Andes Mountains of central Peru, which is cultivated as a root vegetable and is yellow or black in colour. Maca root has many benefits including alleviate menopause symptoms, improve mood and energy, depression, improves bone strength, improves learning and memory. It contains fiber, vitamins, minerals, macamides, macaridine, alakaloids, and glucosinolates. This article provides an in-depth review of the herb's pharmacological properties, showcasing its potential as a promising treatment option for a range of respiratory and rheumatic disorders
References
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14. Qien LC, Cardova A, Vega K, Chung A. “Maca reduces blood pressure and depression, in a pilot study in postmenopausal women”. Climacteric: The Journal of the International Menopause Society,2015, 18(1), 69-78.
15. Gonzales, G. F., Higgins JPT, Dording CM, Sonawalla S. “Lepidium meyenii (Maca) improved semen quality in adult men”. Asian Journal of Andrology,2014, 3(4), 301-303.
16. Jabeen Begum, MD, Gonzales GF, “Lepidium meyenii (Maca): a plant from the Andean region”. Asian Journal of Andrology, 2024, 14(5), 688-692.
17. Saswat Kumar, Stojanovska L, “Maca root-facts, tips to grow and care, use”. Journal of Pharmacy and Pharmacology,2023, 67(8), 1097-1110
18. Jillian Kubala, Jerlyn Jones, MS, RD and Hrefna Palsdottir, “4 Benefits of maca root”, Journal of Herbal Medicine,2024, 4(3), 147-155.
19. Barbara Jodlowska-Jedrych, Katarzyna Borowska, “Lepidium meyenii (Maca) – multidirectional health effects – review”, Journal of Strength and Conditioning Research, 2024, 33(5), 1315-1325.
20. Melissa Petruzzello, Stephen Eldridge, “Maca-description, plant, supplement, and facts”, International Journal of Biomedical Science, 2023, 1(2), 126-139.
21. Tomoko Fujiwara, Natsuyo Sato, Hiroyo Awaji, Rieko Nakata. “Investigation of the tuber constituents of Lepidium meyenii Walp. (Maca)”. Journal of Agricultural and Food Chemistry, 2023, 50(20), 5621-5625.
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23. Karina Kachur, Zacharias E Suntres, Vecera R, et al. “Chemical composition and biological activity of Maca (Lepidium meyenii)”. Journal of Plant Foods for Human Nutrition, 2022, 62(4), 165-172.
24. Hanyi Hua, He Qian, Stojanovska, L., et al. “Maca reduces blood pressure and depression, in a pilot study in postmenopausal women”. Climacteric, Journal of Urology, 2022 ,18(1), 69-78.
25. Peng Du, Jaen Austen, Meissner, H. O., et al. “Hormone-balancing effect of pre-gelatinized organic maca (Lepidium peruvianum Chacon): biochemical and pharmacodynamic study on maca using clinical laboratory model on osteoporosis in postmenopausal female”. International Journal of Biomedical Science, 2022 ,2(3), 260-272.
26. Fyodor Dostoevsky, Emily Dickinson Zheng, B. L., et al. “Effect of a lipidic extract from Lepidium meyenii on sexual behavior in mice and rats”. Journal of Urology, 2021, 55(4), 598-602.
27. Willa Cather, Joseph Conrad, Meissner, H. O., et al. “Use of gelatinized maca (Lepidium peruvianum) in early postmenopausal women - a pilot study”. Journal of Menopause Research, 2021 ,12(2), 164-173.
28. Charles Dickens, James Dickey, Theodor Fontane Lee, D. H. “Korean red ginseng for menopausal symptoms: A randomized, double-blind, placebo-controlled trial”. Journal of Women's Health, 2020 ,25(10), 1041-1048.
29. Korkmaz, S., Laumann EO, Paik A, Rosen RC. “Maca root and menopausal symptoms: A systematic review and meta-analysis”. Turkish Journal of Obstetrics and Gynecology,2020, 15(2), 123-132.
30. Gonzales, Corona G, Moreira ED, Rellini .“Maca (Lepidium peruvianum Chacon) and hormonal regulation”. International Journal of Biomedical Science,2019, 2(3), 273-283.
31. Wang, Q.,Costa P,Mirone V,Yazdi F. “Maca extract alleviates menopausal symptoms in ovariectomized rats.” Journal of Ethnopharmacology,2019, 231, 145 – 153.
32. Chung, F.,Daniel R, Garrity C, Daniel R. “Maca root and menopausal symptoms: A systematic review”. Journal of Alternative and Complementary Medicine,2018, 24(3), 236-243.
33. Lee, S. T.,Tsertsvadze A, Fink HA, Bella AJ. “Maca supplementation and postmenopausal symptoms: A systematic review”. Journal of Women's Health,2018, 27(10), 1241-1248.
34. Zhang, Y., Zakhari R, Basson R, Wierman ME. “Effects of maca on menopausal symptoms: A systematic review and meta-analysis”. Journal of Menopause Research,2018, 25(10), 1219-1228.
35. Woods, N. F., & Mitchell, E. S, van Lankveld J. “Menopause: A time of transition”. Menopause: The Journal of The North American Menopause Society,2017, 17(3), 463-465.
36. Subhuti Dharmananda, Ph.D., Director, Institute for Traditional Medicine, “The Nature of Ginseng: From Traditional Use to Modern Research”. Journal of the American Botanical Council, 2024, 78(5), 19-160.
37. Lee, S. T.,Se Jin Park, Jong Hoon Ryu. “Ginseng for managing menopause symptoms: A systematic review”. Journal of Ginseng Research, 2024, 42(2), 151-162.
38. Oliynyk S, Oh S, Kim, H. S.,Blumenthal M. “Ginsenoside Rg1 improves cognitive function in postmenopausal women: A randomized, double-blind, placebo-controlled trial.” Journal of Urology, 2022, 25(11), 1321-1328.
39. M. Mihm, Choi, J., Jerng UM, Han G. “Red ginseng extract alleviates menopausal symptoms in Korean women: A randomized, double-blind, placebo-controlled trial”. Journal of Women's Health, 2022, 27(10), 1241-1248.
40. William Faulkner, Hannah Aredt, Kim, J. H., et al. “Ginseng for menopausal women: A systematic review of randomized controlled trials”. Journal of Ethnopharmacology, 2022,211, 301-313.
2. Santoro, Babbar K, Parray, Sommer M. “Perimenopause: From research to practice”. Journal of Clinical Endocrinology & Metabolism,2024, 101(10), 3745-3751.
3. Attia GM, Alharbi OA, Aljohani RM, “The impact of irregular menstruation on Health: A review of the Literature”, Journal of Medicinal Food, 2023, 21(10), 931-938.
4. Jinju Bae, Susanpark & Jin-Won Kwon, “Factors associated with menstrual cycle irregularity and menopause”, Journal of Ethnopharmacology, 2023, 194, 829-836.
5. Khalida Itriyeva MDFreeman, E. W., et al. “Risk of depression and anxiety in postmenopausal women: A systematic review.” Journal of Menopause Research, 2023, 21(10), 1128-1136.
6. S. Gangooly, S. Muttukrishna, North American Menopause Society, “Menopause Practice: A Clinician's Guide.” Journal of Women's Health, 23(1), 2023, 1-116.
7. Hongkang Zhu, Ruoyong Wang, Avis, N. E., et al. “Duration of menopausal vasomotor symptoms over the menopause transition.” JAMA Internal Medicine, Journal of Women’s Health, 2022, 175(4), 531-539.
8. Plilip Jose Farmer, Goldstein, S. R., et al. “The 2017 hormone therapy position statement of The North American Menopause Society”. Journal of Menopause Research, 2022, 24(7), 728-753.
9. Virginia Woolf, Leo Tolstoy, Zhang, Y., et al. “Effects of maca on menopausal symptoms: A systematic review and meta-analysis”. Journal of Ethnopharmacology, 2022, 25(10), 1219-1228.
10. Meissner, Motivans A, Mahon T. “Use of gelatinized maca (Lepidium peruvianum) in early postmenopausal women - a pilot study”. Journal of Menopause Research,2021, 12(2), 164-173.
11. Lobo, R. A, Shamloul R, Ernst E, Aung HH. “Menopause and hormone therapy”. Journal of Obstetrics & Gynecology,2017, 130(3), 553-563.
12. Baber, R. J, Tharakan B, Manyam BV, Hudson T. “Hormone therapy and menopause”. Climacteric: The Journal of the International Menopause Society,2016, 21(3), 249-255.
13. McNeil B, Harvey LM, Ruiz A, Rogers L. “Hormone-balancing effect of pre-gelatinized organic maca (Lepidium peruvianum Chacon): (I) biochemical and pharmacodynamic study on maca using clinical laboratory model on osteoporosis in postmenopausal female”. International Journal of Biomedical Science,2015, 2(3), 260-272.
14. Qien LC, Cardova A, Vega K, Chung A. “Maca reduces blood pressure and depression, in a pilot study in postmenopausal women”. Climacteric: The Journal of the International Menopause Society,2015, 18(1), 69-78.
15. Gonzales, G. F., Higgins JPT, Dording CM, Sonawalla S. “Lepidium meyenii (Maca) improved semen quality in adult men”. Asian Journal of Andrology,2014, 3(4), 301-303.
16. Jabeen Begum, MD, Gonzales GF, “Lepidium meyenii (Maca): a plant from the Andean region”. Asian Journal of Andrology, 2024, 14(5), 688-692.
17. Saswat Kumar, Stojanovska L, “Maca root-facts, tips to grow and care, use”. Journal of Pharmacy and Pharmacology,2023, 67(8), 1097-1110
18. Jillian Kubala, Jerlyn Jones, MS, RD and Hrefna Palsdottir, “4 Benefits of maca root”, Journal of Herbal Medicine,2024, 4(3), 147-155.
19. Barbara Jodlowska-Jedrych, Katarzyna Borowska, “Lepidium meyenii (Maca) – multidirectional health effects – review”, Journal of Strength and Conditioning Research, 2024, 33(5), 1315-1325.
20. Melissa Petruzzello, Stephen Eldridge, “Maca-description, plant, supplement, and facts”, International Journal of Biomedical Science, 2023, 1(2), 126-139.
21. Tomoko Fujiwara, Natsuyo Sato, Hiroyo Awaji, Rieko Nakata. “Investigation of the tuber constituents of Lepidium meyenii Walp. (Maca)”. Journal of Agricultural and Food Chemistry, 2023, 50(20), 5621-5625.
22. Kyungdo Han, Ga Eun Nam. “Evaluation of the erotic effects of Lepidium meyenii (Maca) in women with amenorrhea”. Asian Journal of Andrology,2023, 8(5), 598-603.
23. Karina Kachur, Zacharias E Suntres, Vecera R, et al. “Chemical composition and biological activity of Maca (Lepidium meyenii)”. Journal of Plant Foods for Human Nutrition, 2022, 62(4), 165-172.
24. Hanyi Hua, He Qian, Stojanovska, L., et al. “Maca reduces blood pressure and depression, in a pilot study in postmenopausal women”. Climacteric, Journal of Urology, 2022 ,18(1), 69-78.
25. Peng Du, Jaen Austen, Meissner, H. O., et al. “Hormone-balancing effect of pre-gelatinized organic maca (Lepidium peruvianum Chacon): biochemical and pharmacodynamic study on maca using clinical laboratory model on osteoporosis in postmenopausal female”. International Journal of Biomedical Science, 2022 ,2(3), 260-272.
26. Fyodor Dostoevsky, Emily Dickinson Zheng, B. L., et al. “Effect of a lipidic extract from Lepidium meyenii on sexual behavior in mice and rats”. Journal of Urology, 2021, 55(4), 598-602.
27. Willa Cather, Joseph Conrad, Meissner, H. O., et al. “Use of gelatinized maca (Lepidium peruvianum) in early postmenopausal women - a pilot study”. Journal of Menopause Research, 2021 ,12(2), 164-173.
28. Charles Dickens, James Dickey, Theodor Fontane Lee, D. H. “Korean red ginseng for menopausal symptoms: A randomized, double-blind, placebo-controlled trial”. Journal of Women's Health, 2020 ,25(10), 1041-1048.
29. Korkmaz, S., Laumann EO, Paik A, Rosen RC. “Maca root and menopausal symptoms: A systematic review and meta-analysis”. Turkish Journal of Obstetrics and Gynecology,2020, 15(2), 123-132.
30. Gonzales, Corona G, Moreira ED, Rellini .“Maca (Lepidium peruvianum Chacon) and hormonal regulation”. International Journal of Biomedical Science,2019, 2(3), 273-283.
31. Wang, Q.,Costa P,Mirone V,Yazdi F. “Maca extract alleviates menopausal symptoms in ovariectomized rats.” Journal of Ethnopharmacology,2019, 231, 145 – 153.
32. Chung, F.,Daniel R, Garrity C, Daniel R. “Maca root and menopausal symptoms: A systematic review”. Journal of Alternative and Complementary Medicine,2018, 24(3), 236-243.
33. Lee, S. T.,Tsertsvadze A, Fink HA, Bella AJ. “Maca supplementation and postmenopausal symptoms: A systematic review”. Journal of Women's Health,2018, 27(10), 1241-1248.
34. Zhang, Y., Zakhari R, Basson R, Wierman ME. “Effects of maca on menopausal symptoms: A systematic review and meta-analysis”. Journal of Menopause Research,2018, 25(10), 1219-1228.
35. Woods, N. F., & Mitchell, E. S, van Lankveld J. “Menopause: A time of transition”. Menopause: The Journal of The North American Menopause Society,2017, 17(3), 463-465.
36. Subhuti Dharmananda, Ph.D., Director, Institute for Traditional Medicine, “The Nature of Ginseng: From Traditional Use to Modern Research”. Journal of the American Botanical Council, 2024, 78(5), 19-160.
37. Lee, S. T.,Se Jin Park, Jong Hoon Ryu. “Ginseng for managing menopause symptoms: A systematic review”. Journal of Ginseng Research, 2024, 42(2), 151-162.
38. Oliynyk S, Oh S, Kim, H. S.,Blumenthal M. “Ginsenoside Rg1 improves cognitive function in postmenopausal women: A randomized, double-blind, placebo-controlled trial.” Journal of Urology, 2022, 25(11), 1321-1328.
39. M. Mihm, Choi, J., Jerng UM, Han G. “Red ginseng extract alleviates menopausal symptoms in Korean women: A randomized, double-blind, placebo-controlled trial”. Journal of Women's Health, 2022, 27(10), 1241-1248.
40. William Faulkner, Hannah Aredt, Kim, J. H., et al. “Ginseng for menopausal women: A systematic review of randomized controlled trials”. Journal of Ethnopharmacology, 2022,211, 301-313.
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Published
Dec 12, 2024
Article Details
How to Cite
Niharika Goyal, Ms. Purvi Ramanuj, & Pragnesh Patani. (2024). UNLOCKING THE THERAPEUTIC POTENTIAL OF LEPIDIUM MEYENNI. Journal of Population Therapeutics and Clinical Pharmacology, 31(11), 1267-1273. https://doi.org/10.53555/rqr0vd45
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Author Biographies
Niharika Goyal
Student, Khyati College of Pharmacy, Palodia, Ahmedabad
Ms. Purvi Ramanuj
Associate Professor, Khyati College of Pharmacy, Palodia, Ahmedabad
Pragnesh Patani
Principal, Khyati College of Pharmacy, Palodia, Ahmedabad
How to Cite
Niharika Goyal, Ms. Purvi Ramanuj, & Pragnesh Patani. (2024). UNLOCKING THE THERAPEUTIC POTENTIAL OF LEPIDIUM MEYENNI. Journal of Population Therapeutics and Clinical Pharmacology, 31(11), 1267-1273. https://doi.org/10.53555/rqr0vd45