BEHAVIORAL SYMPTOMS AND COGNITIVE IMPAIRMENT IN ALZHEIMER’S PATIENTS: A CROSS-SECTIONAL STUDY
Main Article Content
Keywords
Alzheimer’s disease, cognitive impairment, behavioral symptoms, neuropsychiatric symptoms, caregiver burden
Abstract
Objectives: The primary objective of this case-control, cross-sectional study will be to assess the cognitive reserve model in AD by comparing the identified levels of cognitive impairment of AD with different severities of neuropsychiatric symptoms.
Materials and Methods
Overall 120 of the Alzheimer’s were evaluated for cognitive function based on the MMSE and for behavior based on the NPI.
Results
Overall, 70% of patients assessed had at least one neuropsychiatric symptom, whereas apathy had the highest prevalence rate of 55%. A significant negative relationship between MMSE and NPI was established; r=- 0.75, meaning a higher level of cognitive dysfunction is associated with a higher level of behavioural disturbances.
Conclusion
It also highlights that much of the treatment approaches for Alzheimer’s disease have to include both the cognitive and behavioural components presented and their interaction significantly influences the level of presented distress among patients with Alzheimer’s disease and their caregivers.
References
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Muhammad Imran Khan
Consultant Psychiatrist, Khyber Teaching Hospital Peshawar, Pakistan
Taimur Khan
Psychiatric Resident, Khyber Teaching Hospital Peshawar, Pakistan
Sana Zain
Senior Registrar, Department of Psychiatry, Indus Medical College University of Modern Science, Tando Muhammad khan, Pakistan
Muhammad Sannan
Department of Psychiatry, Khyber Medical College, Peshawar, Pakistan
Seemab Azeem
Mental Health Case Manager, Department of International Medical Corps
Muhammad Tariq
Assistant Professor, Department of Psychiatry Sahara Medical College Narowal Punjab, Pakistan