PREDICTIVE VALUE OF FINE NEEDLE ASPIRATION CYTOLOGY VERSUS ULTRASOUND TI-RADS IN SOLITARY THYROID NODULE COMPARING WITH GOLD STANDARD
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Keywords
Thyroid nodules, euthyroid, FNAC, Ultrasound
Abstract
Background: Thyroid nodule characteristics are evaluated by ultrasound, which helps direct further investigation or treatment. Fine needle aspiration cytology (FNAC) is used for diagnosis when required. Thyroid carcinoma is the most common endocrine cancer, although being extremely rare. By 2030, it is expected to rise to the fourth rank of all cancers in the US. In the US, its yearly incidence has increased by 500%. Thyroid cancer is more common in women and has a very variable prevalence by geographic area. There has been rise in thyroid cancer cases in Pakistan.
Objective: To assess the predictive efficacy of FNAC and ultrasonography TI-RADS in the evaluation of single thyroid nodules.
Study design: Cross-sectional study
Place and Duration: This study was conducted in Liaquat University of Medical and Health Sciences Jamshoro from March 2023 to March 2024
Methodology: All the participants of this research were aged 18 years and above. All of the participants were having thyroid nodules and their informed consent was obtained. Details were kept of the patient's residence, gender, age, comorbidities, and history of thyroid illness, among other demographic and clinical details. Thyroid function tests (serum TSH and free T4) were performed on participants with thyroid nodules utilizing the CLIA 1000 analyzer. The study sample consisted solely of euthyroid patients who underwent fine needle aspiration cytology (FNAC) and high-resolution ultrasonography. IBM SPSS version 25 was used for the statistical analysis, which included the Fisher exact test and the Chi-square test.
Results: There were a total of 300 participants involved in this research. The average age was 41.7 years. Most of the participants were from the age group of 40 years to 60 years. Majority of the participants were females, representing 68% of the total population.
Conclusion: In conclusion, when assessing euthyroid patients with isolated thyroid nodules, ultrasonography is a useful adjunct to FNAC.
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All articles published in JPTCP are licensed under Copyright Creative Commons Attribution-NonCommercial 4.0 International License.
Shah Nawaz Khatti
Assistant Professor General Surgery, Liaquat University of Medical and Health Sciences Jamshoro Pakistan.
Imtiaz Ali Soomro
Assistant Professor General Surgery, Peoples University of Medical and Health Sciences Nawabshah Pakistan
Muhammad Ghazi Asad Khan
Graduate, Liaquat University of Medical and Health Sciences Jamshoro Pakistan.
Imtiaz Ali Langah
Assistant Professor General Surgery, Peoples University of Medical and Health Sciences Nawabshah Pakistan
Ahmed Hussain Pathan
Associate Professor General Surgery, Liaquat University of Medical and Health Sciences Jamshoro Pakistan
Rizwan Ali
Medical Officer, Liaquat University Hospital Hyderabad/Jamshoro Pakistan.