OCCURRENCE OF SPONTANEOUS BACTERIAL PERITONITIS IN INDIVIDUALS WITH UPPER GASTROINTESTINAL BLEEDING WITHIN THE CONTEXT OF DECOMPENSATED CHRONIC LIVER DISEASE
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Keywords
Spontaneous bacterial peritonitis, Child-Pugh Class, uppe gastrointestinal bleeding, chronic liver disease
Abstract
Objectives: To assess the occurrence of spontaneous bacterial peritonitis in patients with decompensated chronic liver disease who present with upper gastrointestinal bleeding.
Materials and Methods: Following ethical committee approval, this study was conducted in the Gastroenterology Department, DG Khan Medical College DG Khan, Pakistan and Shaikh Zayed Hospital, Lahore in the duration from November 2023 to April 2024. 110 patients meeting selection criteria were enrolled. Each patient underwent clinical exams and lab tests to assess Child-Pugh class and diagnose liver cirrhosis. Patients with decompensated chronic liver disease and upper gastrointestinal bleeding (Child-Pugh Class B and C) were evaluated for spontaneous bacterial peritonitis (SBP), confirmed by specific lab criteria.
Results: The mean age of the 110 patients was 48.04 years (SD 8.46). Of these, 55.5% were male and 44.5% female. Child-Pugh classifications showed 43.6% in Class B and 56.4% in Class C. Spontaneous bacterial peritonitis (SBP) prevalence was 30%. SBP occurrence was stratified by gender and age, with p-values of 0.25 and 0.57, respectively.
Conclusion: Spontaneous bacterial peritonitis is more common in people with upper gastrointestinal bleeding and advanced chronic liver disease, especially those in Child-Pugh Class C compared to Class B.
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Muhammad Amjad Khan
Consultant Gastroenterologist, Medical Unit, DHQ Hospital, Abbottabad, Pakistan
Kashif Ali
Assistant Professor, Department of Medicine, DG Khan Medical College DG Khan, Pakistan
Syed Asif Raza Zaidi
Assistant Professor of Gastroenterology, Shaikh Zayed Hospital, Lahore
Asim Shehzad
Assistant Professor, Department of Gastroenterology, Fauji Foundation Hospital, Rawalpindi, Pakistan
Intikhab Alam
Assistant Professor Gastroenterology, Jinnah Medical College and Teaching Hospital, Peshawar, Pakistan
Rizwan Ur Rehman
District Specialist Gastroenterology, DHQ Teaching Hospital, KDA Kohat, Pakistan
Naba Shabbir
Lecturer, Rashid Latif College of Pharmacy, Lahore, Pakistan
Hosam Alazazzi
Royal College of Surgeons in Ireland - Bahrain
Kamel J. K. Walwil
Royal College of Surgeons in Ireland - Bahrain
Jumana Abdelrahman Diab
Royal College of Surgeons in Ireland - Bahrain