A PRELIMINARY STUDY TO DETERMINE THE EFFECT OF ESOMEPRAZOLE MAGNESIUM (NEXIUM) ON STOMACH ACIDITY
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Keywords
esomeprazole magnesium, Nexium, stomach acidity, gastroesophageal reflux disease (GERD), pH monitoring
Abstract
This preliminary study aimed to determine the effect of esomeprazole magnesium (Nexium) on stomach acidity. The study utilized a randomized controlled trial design with a sample size of 50 participants who were diagnosed with gastroesophageal reflux disease (GERD). The participants were divided into two groups: one group received esomeprazole magnesium for a period of four weeks, while the other group received placebo. Stomach acidity levels were measured at baseline and at the end of the four-week period using pH monitoring techniques. The results showed a significant decrease in stomach acidity levels in the group that received esomeprazole magnesium compared to the placebo group. This suggests that esomeprazole magnesium is effective in reducing stomach acidity in patients with GERD. Further research with a larger sample size and longer follow-up period is recommended.
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Dania Mustafa Ghulam
Pharmasict Pharm.D, King Fahd General Hospital Jeddah
Dalal Abdulfattah Sukaik
Pharmacy technician, King Fahd General Hospital Jeddah
Rahmah Ahmed Alsaeed
Pharmacy technician, King Fahd General Hospital Jeddah
Haneen Hamad Alrefai
Pharmacy technician, Khulais Hospital
Nawal Saeed Hassan Alkhaldi
Pharmacy technician, Maternity and Children's Hospital in Al-Kharj
Sarah Ali Alfaraj
Pharmacy technician , Qatif Central hospital