INVESTIGATING THE OCCURRENCE AND IMPACT OF CYTOMEGALOVIRUS (CMV) IN KIDNEY TRANSPLANT RECIPIENTS AT REHMAN MEDICAL INSTITUTE, PESHAWAR: A COMPREHENSIVE ANALYSIS
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Keywords
CMV, Kidney Transplant, PCR
Abstract
Background: Cytomegalovirus (CMV) infection poses a significant challenge in kidney transplantation, potentially jeopardizing graft function and overall patient well-being. Therefore, our study aim is to identify frequency of CMV infection in kidney transplant patients.
Material And Methods: The study design used was a cross-sectional descriptive study. A total of 213 kidney transplant recipients were included in the study, chosen using systematic random sampling. Inclusion criteria encompassed individuals who had successfully undergone kidney transplantation at RMI hospital. Demographic and clinical data were obtained from medical records, covering factors such as age, gender, and transplant date. The prevalence of CMV infection was determined through laboratory tests, with a particular emphasis on Quantitative Polymerase Chain Reaction (PCR) assays capable of detecting CMV DNA in various materials.
Results: The results of the study demonstrated a notably higher prevalence of CMV infection among male kidney transplant patients. This disparity was especially prominent in the 18-35 years age group. Additionally, a significant prevalence of CMV was observed in patients aged 36-66 years.
Conclusion: The findings underscore the significance of gender and age in the context of CMV infection among kidney transplant patients. These insights prompt the need for tailored preventative and therapeutic strategies in the management of kidney transplant recipients at Rehman Medical Institute and potentially in similar contexts.
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Mansoor Ahmad Khan
Department of Rehman College of Allied Health Sciences RMI, Peshawar, Pakistan
Tanveer Ahmad
Department of Rehman College of Allied Health Sciences RMI, Peshawar, Pakistan
Hassan Zeb
Department of Rehman College of Allied Health Sciences, Peshawar, Pakistan
Ikram ul Haq
Department of Rehman College of Allied Health Sciences, Peshawar, Pakistan
Mohammad Sadiq Shah
Department of Rehman College of Allied Health Sciences, Peshawar, Pakistan
Muhammad Imtiaz Khan
Department of Rehman College of Allied Health Sciences, Peshawar, Pakistan
Yusra Tabassum
Gandhara university (Kabir Institute of Public health) Peshawar, Pakistan
Usama Ilahi
Center for biotechnology and microbiology UOS university of swat.
Shahid Ali
Center for biotechnology and microbiology UOS university of swat.
Junaid Hameed
Department of Rehman College of Allied Health Sciences, Peshawar, Pakistan