ANXIOLYTIC AND MEMORY BOOSTING EFFECT OF FRUIT COCKTAIL (CHERRY JUICE, PINEAPPLE JUICE AND COCONUT MILK)

Abstract

Anxiety is an emotion of uneasiness, fear or discomfort. It causes restlessness and difficulty in focus. Recently due to the high costs of allopathic medicines and increasing adverse effects, the trend has switched to exploring nutrients in a normal diet that can be therapeutically beneficial. Cherry, pineapple and coconut milk have a great impact on CNS activity because they contain different flavonoids and other phytochemicals. This study was designed to assess the anxiolytic and memory-boosting potential of a cocktail of cherry juice, pineapple juice and coconut milk. This study was performed on albino mice weighing 18-22gm of both sexes. Mice were divided into 2 groups. Group I was taken as Control and was given normal saline 0.4ml. Group II was taken as treated and given a cocktail of 0.4ml. Head dip, light and dark model, cage crossing, open field and elevated plus maze were used to evaluate effects on anxiety. A stationary rod test was used to evaluate memory-boosting effects. Our study showed significant anxiolytic activities (p ≤ 0.05) of cocktails in mice. Head dip activity, light and dark activity, cage crossing activity, and elevated plus maze show highly significant (p≤ 0.001) results on anxiety. Open field activity showed significant (p ≤0.05) results on anxiety. Stationary rod activity showed highly significant (p ≤ 0.001) results on the memory-boosting effect. It is concluded that the administration of a cocktail has anxiolytic and positive effects on memory because it possesses anti-oxidant components such as multivitamins, minerals and flavonoids. It has fewer adverse effects as compared to allopathic drugs.