COCAINE TOXICITY AFTER LARYNGOSCOPY IN AN INFANT
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Keywords
Cocaine toxicity, pediatric patients, topical cocaine
Abstract
Iatrogenic cocaine toxicity was observed in a 5.5-month -old male who received intranasal cocaine as a topical anesthetic for laryngoscopy. He became agitated, diaphoretic, tachycardic, and hypertensive shortly following the procedure. To control his signs and symptoms, he required 3 doses of IV lorazepam. Systemic absorption and toxicity can vary amongst individuals, making it difficult to determine appropriate dosing. The maximum dose of 1 mg/kg in children has not been validated and toxicity may appear at a much lower dose in certain individuals. Pediatric patients receiving topical cocaine as an anesthetic must be given the lowest possible dose, and then carefully monitored for signs of systemic absorption.
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