CLINICAL PROFILE & KNOWLEDGE OF SCRUB TYPHUS AMONG PATIENTS ATTENDING THE TERTIARY CARE HOSPITAL – AN ANALYTICAL STUDY

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Neelima varania
Dr. Ritu Bhatnagar

Keywords

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Abstract

Introduction: India is a tropical country with a high burden of febrile zoonotic/infectious illnesses, scrub typhus being such a cause with multiple epidemics reported from different regions of the country. Scrub typhus is the commonest of the rickettsial diseases in India and is difficult to diagnose. Pneumonia and acute respiratory distress syndrome (ARDS) are frequent complications.


Objectives:  1. To assess signs and symptoms occurring in scrub typhus among patients attending the hospital. 2. To estimate the knowledge of scrub typhus among patients.


Material & methods: The study was conducted by Department of Microbiology at PMCH Udaipur from January 2024 to March 2024 and screened for scrub typhus were selected as the study sample. The sample size was calculated as 227 using the Daniel’s formula. A self-administered semi-structured questionnaire was predesigned and pretested Questionnaire to collect data regarding scrub typhus, which was prepared in English and Hindi for data collection. Statistical packages of social sciences (IBM software, version 27) were used to compare the continuous variables between the two groups. P<0.05 will be considered as statistically significant.


Results: The findings of the study revealed that 13.65% of patients were positive for scrub typhus. The most common symptoms among patients were fever (100%), headache (54.18%), nausea/vomiting (23.78%). Out of 227 patients, only 66 (29.07%) had heard about scrub typhus. Among 66 patients, On item wise knowledge, more than half of the patients knew that scrub typhus as infectious disease (50%), transmitted through the bite of mites (59.09%) However, only 16.66% knew that scrub typhus rapidly spread in the rainy season. Occupation is the factor that is significantly associated with scrub typhus at 95% CI, (χ² = 6.667, p = 0.009) at 5% Los.


Conclusion: Our results highlight that scrub typhus infection is an important cause of AFI, and patients must be routinely screened for the proper diagnosis and timely treatment. Moreover, very few had heard about scrub typhus and its preventive measures, so awareness program on scrub typhus is needed for the risk groups to enhance their knowledge.

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References

1. Guidelines for diagnosis and management of rickettsial diseases in India. New Delhi: Department of Health Research Director General, Indian Council of Medical Research; 2015 February. 20p.
2. Poomalar GK, Rekha R. A Case Series Of Scrub Typhus In Obstetrics. J Clin Diagn Res 2014; 8:OR01–OR03.
3. Chang WH. Current status of tsutsugamushi disease in Korea. J Korean Med Sci 1995;10:227 38. doi: 10.3346/jkms. 1995.10.4.227.
4. Tilak R, Kunwar R, Tyagi PK, Khera A, Joshi RK, Wankhade UB. Zoonotic surveillance for rickettsiae in rodents and mapping of vectors of rickettsial diseases in India: A multicentric study. Indian J Public Health 2017;61:174 81. doi: 10.4103/ ijph.IJPH_156_17.
5. Lyu Y, Tian L, Zhang L, Dou X, Wang X, Li W, et al. A casecontrol study of risk factors associated with scrub typhus infection in Beijing, China. PLoS One 2013;8:e63668.
6. Zhang M, Zhao ZT, Wang XJ, Li Z, Ding L, Ding SJ, et al. Scrub typhus: Surveillance, clinical profile and diagnostic issues in Shandong, China. Am J Trop Med Hyg 2012;87:1099-104.
7. Griffith M, Peter JV, Karthik G, Ramakrishna K, Prakash JA, Kalki RC, et al. Profile of organ dysfunction and predictors of mortality in severe scrub typhus infection requiring intensive care admission. Indian J Crit Care Med 2014;18:497-502.
8. Center for Disease Control and Prevention. Scrub Typhus; 2019. Available from: https://www.cdc.gov/typhus/scrub/ index.html on 2019-6-26
9. Peter JV, Sudarsan TI, Prakash JA, Varghese GM. Severe scrub typhus infection: Clinical features, diagnostic challenges and management. World J Crit Care Med 2015;4:244-50.
10. Thapa S, Sapkota LB, Hamal P. Threat of scrub typhus in postearthquake Nepal. J Chitwan Med Coll 2016;6:1-6.
11. Liu Q, Panpanich R. Anitbiotics for treating scrub typhus. Cochrane Database of Systematic Reviews 2002; Issue 3 Art No. CD002159
12. Kumar, Devendra; Jakhar, Saha Dev Emerging trends of scrub typhus disease in southern Rajasthan, India Journal of vector borne diseases; Oct - Dec 2022; 303-311
13. Daniel WW (1999), Biostatistics: A foundation for Analysis in the Health Sciences, 7th Ed. New York: John Wiley & Sons.
14. Imandar S, Thunga G, Acharya R, et al. Study of Clinical Characteristics and Treatment Pattern of Scrub Typhus in Tertiary Care Hospital. J Pharmaceut Sci Res 2013; 5:107–110.
15. Abhilash KP, Gunasekaran K, Mitra S, et al. Scrub typhus menigitis: An underrecognised cause of aseptic menigitis in India. Neurol India 2015; 63:209-14
16. Bibhuti Saha, SoumyadipChatterji, Kaushik Mitra, Shibendu Ghosh et. al. Socio-demographic and Clinico-Epidemiological Study of Scrub Typhus in Two Tertiary Care Hospitals of Kolkata. Journal of The Association of Physicians of India; 2018
17. Gautam R, Parajuli K, Sherchand JB. Epidemiology, risk factors and seasonal variation of scrub typhus fever in central Nepal. Trop Med Infect Dis 2019;4:e27.
18. Kalpana Sharma, Mamata Sharma Neupane, Sunita Poudyal, Hem Kumari Subba Prevalence and knowledge of scrub typhus in patients with acute febrile illness in teaching hospital, Chitwan, Nepal; International Journal of Medical Science and Public Health; 2019; 897 – 901
19. Kim DS, Acharya D, Lee K, Yoo SJ, Park JH, Lim HS, et al. Awareness and work-related factors associated with scrub typhus: A case-control study from South Korea. Int J Environ Res Public Health 2018;15:e1143.