PHYSIOLOGICAL AND PATHOLOGICAL IMPACT OF HEPATITIS B AND C, PUBLIC HEALTH STRATEGIES FOR PREVENTION AND CONTROL
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Keywords
Hepatitis B, Hepatitis C, Liver Function, Cirrhosis, Public Health, Pakistan
Abstract
Objectives: The goal of this study is to analyze the physiological and pathological impacts of hepatitis B and C on liver and to measure the effectiveness of the health-related prevention and control programs in Pakistan.
Materials and Methods: This was a cross-sectional and prospective investigation of 200 patients with chronic hepatitis B or C in Karachi, Pakistan, who were evaluated with liver function tests (ALT, AST), abdominal ultrasonography, and serological markers. Demographic factors, health behavior, and medical history data were also captured.
Results: Both hepatitis B and C patients were shown to have increased ALT and AST, with hepatitis C presenting higher results for both tests. In contrast, 40% of hepatitis C patients were shown to have cirrhosis via ultrasound examination compared to 20% of hepatitis B patients. A large proportion of the participants came from low household incomes, and many did not know their infection status.
Conclusion: Hepatitis B and C are medically categorized as Liver disorders with Hepatitis C being more dangerous to the liver than Hepatitis B. As a result, early diagnosis and intervention were critical for improving health status.
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Muhammad Israr Ul Haq
Assistant Professor, Department of Gastroenterology, Sheikh Zayed Medical College Rahim Yar Khan, Pakistan
Saeed Anwar
Consultant Gastroenterologist and Hepatologist, Surriya Medical and Gynae Centre Jhelum, Pakistan
Ghazala Yasmeen Iqbal
Assistant Professor, Department of Community Medicine, Sheikh Zayed Medical College Rahim Yar Khan, Pakistan
Hafiz Umer Farooq
Assistant Professor, Department of Community Medicine, Sheikh Zayed Medical College Rahim Yar Khan, Pakistan
Sonia Nisar
Senior Demonstrator, Department of Community Medicine, Sheikh Zayed Medical College Rahim Yar Khan, Pakistan
Hatf Rana
AMS RYK Medical College and Hospital, Rahim Yar Khan, Pakistan