FORMULATION OF ETHYL CELLULOSE MICROSPHERES OF IBUPROFEN AND IT’S CHARACTERIZATION
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Keywords
Ethyl Cellulose, Drug Formulation, Controlled Release, Characterization, Microspheres, buprofen
Abstract
Microspheres are the drug delivery system (NDDS) which is a controlled release dosage form to maintain the constantdrug concentration in plasma, as in microspheres the drug is released at a predetermined rate for extended period of time. The aim of the project was to form microspheres of ibuprofen by using ethylcellulose in various drug to polymer ratios. Ethylcellulose was used as a carrier in formulation of Ibuprofen (a non-steroidal anti-inflammatory drug) microsphere. Various formulation techniques were performed on the prepared dosage form.Highest loading was obtained by increasing the amount of Ibuprofen with respect to polymer.
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Omer Mahmood Mumtaz
Lecturer, Department of Pharmacy, Minhaj University Lahore
Zahbia Roohani
Lecturer, Department of Pharmacy, Minhaj University Lahore
Azzah Khadim Hussain
MPhil Pharmaceutics, University of Central Punjab
Muhammad Hassan Naru
University College of Pharmacy, University of the Punjab, Pharmacist (BPS-17), Primary and Secondary Healthcare Department
Ahmad Ibne Yousaf
School of Human Nutrition & Dietetics / Academic Officer, Minhaj University Lahore
Saif Ullah Khan
Lecturer, Department of Pharmacy, Minhaj University Lahore