EXPLORING THE SYNERGISTIC EFFECTS OF CATHARANTHUS TRICOPHYLLUS AND COCONUT OIL ON HUMAN HEALTH: A REVIEW OF THE EVIDENCE
Main Article Content
Keywords
Anti cancer, Sadabahar, Baramasi,
Abstract
Catharanthus roseus is a beautiful flowering perennial herb which is always in bloom as ornamental plant. It is known as Madagascar periwinkle. This plant characterized as terpenoids indole alkaloid producing plant cultivated in warm region. Besides alkaloid it is rich in phenolic compounds, organic acids and amino acid of pharmacological significance in its different parts. Traditionally, this herbal plant is boon to provide protective action for many deadly health problems being faced by humans by their direct or indirect usage in skin disease, high blood pressure, rheumatism, menstrual disorders, indigestion etc. But nowadays, transition to modern and formulated treatment has been increased.
References
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2. J Zhu, M Wang, W Wen and R Yu (2015). “Biosynthesis and regulation of terpenoid indole alkaloids in Catharanthus roseus,” Pharmacognosy reviews, 9(17), 24-28
3. N Nejat, A Valdiani, D Cahill, et.al. (2015). “Ornamental exterior versus therapeutic interior of madagascar periwinkle (Catharanthus roseus): The two faces of a versatile herb,” Scientific World Journal, 2015, 1-19.
4. P Mishra, G.C. Uniyal, S. Sharma and S Kumar (2001). “Pattern of diversity for morphological and alkaloid yield related traits among the periwinkle Catharanthus roseus accessions collected from in and around Indian subcontinent,” Genetic Resources and Crop Evolution, 48, 273-276.
5. R Rajeev and M Kumar (2020). “ Biochemical profile of Vinca rosea Linn (Catharanthus roseus G. Don),” IOSR Journal of Biotechnology and Biochemistry, 6(5), 13-26.
6. S Mohammad Azharhusain, B Shrivastava, A Quazi, et al (2022). “A review on Guggulu Wightii (ARN.) Bhand.], its phytochemical constitution and mode of action,” International Journal of Ayurveda and Pharma Research, 10(5), 74-79
7. J Aslam, S Haque Khan, Z Hameed Siddiqui, et al (2010). “ Catharanthus roseus (L.) G. Don. An important drug: It’s applications and production, Pharmacie Globale:” International Journal of Comprehensive Pharmacy, 1(4), 1-16
8. D Leveue and F Jehl (2007). “Molecular pharmaceutical of Cathranthus (Vinca) alkaloids,” The Journal of Clinical Pharmacology, 47(5), 579-588.
9. S Nobili, D Lippi, E Witort, et al (2009). “Natural compounds for cancer treatment and prevention,” Pharmacological Research, 59(6), 365-378.
10. S D Dwivedi, M Sharma, et al (2013) “Antimicrobial Activity of Catharanthus roseus,” Chemistry and Materials Research, 3(9), 61-64.
11. E H Sanjaya (2015). “Phytochemical screening and antibacterial activity of different fractions of Indonesian vinca rosea leaves (Catharanthus roseus L. G. Don),” Journal of Chemical and Pharmaceutical Research, 7(11), 144-146.
12. S.E. Gomaa, M Yahayu, M Nurjayadi, et al (2019). “Antimicrobial compounds from Catharanthus roseus-“ A review, International Journal of Scientific & Technology Research, 8, 113-121.
13. P Goyal, A Khanna, A Chauhan, et al (2008). “ In vitro evaluation of crude extracts of Catharanthus roseus for potential antibacterial activity”, International Journal of Green Pharmacy, 2(3), 176-181.
14. S N Singh, P Vats, S Suri, et al (2021). “ Effect of an antidiabetic extract of Catharanthus roseus on enzymic activities in streptozotocin induced diabetic rats”, Journal of Ethnopharmacology, 76(3), 269-277.
15. R R Chattopadhyay (1999). “A comparative evaluation of some blood sugar lowering agents of plant origin,” Journal of Ethnopharmacology, 67(3), 367-372.
16. S Pandey, K Gupta K and A K Mukherjee (2007). “Impact of cadmium and lead on Catharanthus roseus– A phytoremediation study,” Journal of Environmental Biology, 28(3), 656-662.
17. R B Meagher (2000). “Phytoremediation of toxic elemental and organic pollutants”, Current Opinion in Plant Biology, 3(2), 153-162
18. J Narayan Mishra and N Kumar Verma (2017). “A brief study on Catharanthus Roseus: A review”, International Journal of Research in Pharmacy and Pharmaceutical Sciences, 2(2), 20-23.
19. S Das and A B Sharangi (2017). “Madagascar periwinkle (Catharanthus roseus L.): Diverse medicinal and therapeutic benefits to humankind,” Journal of Pharmacognosy and Phytochemistry, 6(5), 1695-1701.
20. B.S. Nayak, M. Anderson and L.M. Pinto Pereira (2007). “ Evaluation of wound-healing potential of Catharanthus roseus leaf extract in rats, Fitoterapia,” 78(7-8), 540-544.
21. A. M. Marina, Y. B. Che Man, S. A. H.Nasimah, I. Amin, “ Chemical propertiesof virgin coconut oil.” J. Amer. OilChem. Soc., 2009 86 301-307.
22. Thampan, P.K., Glimpses of coconutindustry in India, CoconutDevelopment Board, Cochin 1988.
23. Baltasar S.F. “ Coconut oil extractionemploying the dry processingtechnology. Phillip. J. Coconut Studies,1977 2 (4) 40-42.
24. Aliwalas A.R., Buccat C.P., “Filtration-extraction of granulated coconut on abench scale”. Phillip. J. Sci., 1970, 96(3) 215-285.
25. Bellenand J.F., Baloutch G., Ong N.;Lecerf J., “Effects of coconut oil on heartlipids and on fatty acid utilization inrapeseed oil.” Lipids, 1980 15 (11) 938-943.
26. Banzon J.A., Resurreccion A.P., “Fattyacid distribution in coconut oil obtainedby four processing methods and securedfrom four Philippine types of coconuts.Phillip”. J. Coconut Studies, 1979 4 (2) 10-18.
27. C-Hua Wang, G-Cai Wang, Y Wang, et al (2012). “Cytotoxic dimeric indole alkaloids from Catharanthus roseus”, Fitoterapia, 83(4), 765-769.
28. J Narayan Mishra and N Kumar Verma (2017). “A brief study on Catharanthus Roseus: “A review, International Journal of Research in Pharmacy and Pharmaceutical Sciences, 2(2), 20-23.
29. Y Patel, V Vadgama, S Baxi, Chandrabhanu and B Tripathi (2011). “Evaluation of hypolipidemic activity of leaf juice of Catharanthus roseus (Linn.) G. Donn. In guinea pigs,” Acta Poloniae Pharmaceutica, 68(6), 927-935,
30. M A Bhutkar and S B Bhise (2011). “Comparative studies on antioxidant properties of Catharanthus rosea and Catharanthus”, International Journal of Pharmaceutical Techniques, 3(3), 1551-1556.
31. Abbasi SP, Abbasi ST, Khoharo K, Talpur HK, Siddiqui SM (2014) “Blood glucose lowering effect of Catharanthus roseus in alloxan induced diabetic rats.”Eur J Mol Biol Biochem 1:63–66.
32. Ahmad NH, Rahim RA, Mat I (2010) “ Catharanthus roseus aqueous extract is cytotoxic to jurkat leukaemic t-cells but induces the proliferation of normal peripheral blood mononuclear cells”. Trop Life Sci Res 21:101–113.
33. Ahmed MF, Rao AS (2013) “ Comparative hepatoprotective activities of selected Indian medicinal plants.” Glob J Med Res Pharma Drug Discov Toxicol Med 13(2):15–21.
34. Akhila A (2007) “Metabolic engineering of biosynthetic pathways leading to isoprenoids: mono- and sesquiterpenes in plastids and cytosol.” J Plant Interact 2:1742–9153.
35. Alaguchamy N, Jayakumararaj R (2015) “Larvicidal effect of Catharanthus roseus L (G) Don. Aqueous extracts on the larvae of Heliocoverpa armigera (Hubner)”. Int J Life Sci Educ Res 3:10–14.
36. Archana H, Vasist R, Sharma RB, Gupta A (2016)” Pharmacological reputation of Vinca plant” World J Pharm Pharm Sci 5:1602–1610.
37. Asha A, Vinita P, Hetal J (2015) “In vivo comparative study of different variants of Catharanthus roseus (L.) G. Don. For free radical scavenging activity in type 2 diabetes mellitus”. J de Afrikana 2:74–86.
38. Aslam J, Mujib A, Sharma MP (2014) “Somatic embryos in Catharanthus roseus: a scanning electron microscopic study”. Natulae Scientia Biologicae 6:167–172.
39. Asthana RB, Misra MK (1979)” Orally effective hypoglycemic agent from Vinca rosea”. Ind J Biochem Biophys 16:30–35.
40. Banakar V, Malagi U, Naik R (2007)” Impact of periwinkle leaves (Catharanthus roseus) on management of diabetes mellitus, Karnataka.” J Agric Sci 20:115–119.
41. Benjamin BD, Kelkar SM, Pote MS (1994) “ Catharanthus roseus cell culture: growth, alkaloid synthesis and antidiabetic activity” Phytother Res 8:185–186.
42. Bhutkar MA, Bhise SB (2011) “Comparative studies on antioxidant properties of Catharanthus roseus and Catharanthus alba”. Int J Pharm Technol Res 3:1551–1556.
43. Daly E.M., Taylor R.E. “Entropy and enthalpy in the activity of tubulin-based antimitotic agents”. Curr. Chem. Biol. 2009;3:47–59.
44. Ganapathi B., Kargi F. “Recent Advances in Indole Alkaloid Production by Catharanthus roseus (Periwinkle)” J. Exp. Bot. 1990;41:259–267.
45. Ramani S., Jayabaskaran “Catharanthus Enhanced catharanthine and vindoline production in suspension cultures of Catharanthus roseus by ultraviolet-B light.”J. Mol. Signal. 2008;3:9–14.
46. Ahmad NH, Rahim RA, Mat I (2010) “Catharanthus roseus aqueous extract is cytotoxic to jurkat leukaemic t-cells but induces the proliferation of normal peripheral blood mononuclear cells.” Trop Life Sci Res 21:101–113.
47. Akhila A (2007) “Metabolic engineering of biosynthetic pathways leading to isoprenoids: mono- and sesquiterpenes in plastids and cytosol. J Plant Interact 2:1742–9153.
48. Amini A, Glevarco G, Andreu F, Rideau M, Creche J (2009) “Low levels of gibberellic acid control the biosynthesis of ajmalicine in Catharanthus roseus cell suspension cultures. “Planta Med 75:187–191.
49. Andrade-Cetto A, Heinrich M (2005) “Mexican plants with hypoglycaemic effect used in the treatment of diabetes.” J Ethnopharmacol 99:325–348.
50. Archana H, Vasist R, Sharma RB, Gupta A (2016)” Pharmacological reputation of Vinca plant.”World J Pharm Pharm Sci 5:1602–1610.
51. Ferrari G, Fervidi O, Ferrari M (1971) Phytochemistry. In: “Arnold B (ed) The alkaloid.”Academic Press, London, pp 24-28.
52. Kumar A, Singhal KC, Sharma RA, Govind K, Kumar VV (2012) “Analysis of antioxidant activity of Catharanthus roseus L. and it’s association with habitat temperature. “Asian J Exp Biol Sci 3:706–713
2. J Zhu, M Wang, W Wen and R Yu (2015). “Biosynthesis and regulation of terpenoid indole alkaloids in Catharanthus roseus,” Pharmacognosy reviews, 9(17), 24-28
3. N Nejat, A Valdiani, D Cahill, et.al. (2015). “Ornamental exterior versus therapeutic interior of madagascar periwinkle (Catharanthus roseus): The two faces of a versatile herb,” Scientific World Journal, 2015, 1-19.
4. P Mishra, G.C. Uniyal, S. Sharma and S Kumar (2001). “Pattern of diversity for morphological and alkaloid yield related traits among the periwinkle Catharanthus roseus accessions collected from in and around Indian subcontinent,” Genetic Resources and Crop Evolution, 48, 273-276.
5. R Rajeev and M Kumar (2020). “ Biochemical profile of Vinca rosea Linn (Catharanthus roseus G. Don),” IOSR Journal of Biotechnology and Biochemistry, 6(5), 13-26.
6. S Mohammad Azharhusain, B Shrivastava, A Quazi, et al (2022). “A review on Guggulu Wightii (ARN.) Bhand.], its phytochemical constitution and mode of action,” International Journal of Ayurveda and Pharma Research, 10(5), 74-79
7. J Aslam, S Haque Khan, Z Hameed Siddiqui, et al (2010). “ Catharanthus roseus (L.) G. Don. An important drug: It’s applications and production, Pharmacie Globale:” International Journal of Comprehensive Pharmacy, 1(4), 1-16
8. D Leveue and F Jehl (2007). “Molecular pharmaceutical of Cathranthus (Vinca) alkaloids,” The Journal of Clinical Pharmacology, 47(5), 579-588.
9. S Nobili, D Lippi, E Witort, et al (2009). “Natural compounds for cancer treatment and prevention,” Pharmacological Research, 59(6), 365-378.
10. S D Dwivedi, M Sharma, et al (2013) “Antimicrobial Activity of Catharanthus roseus,” Chemistry and Materials Research, 3(9), 61-64.
11. E H Sanjaya (2015). “Phytochemical screening and antibacterial activity of different fractions of Indonesian vinca rosea leaves (Catharanthus roseus L. G. Don),” Journal of Chemical and Pharmaceutical Research, 7(11), 144-146.
12. S.E. Gomaa, M Yahayu, M Nurjayadi, et al (2019). “Antimicrobial compounds from Catharanthus roseus-“ A review, International Journal of Scientific & Technology Research, 8, 113-121.
13. P Goyal, A Khanna, A Chauhan, et al (2008). “ In vitro evaluation of crude extracts of Catharanthus roseus for potential antibacterial activity”, International Journal of Green Pharmacy, 2(3), 176-181.
14. S N Singh, P Vats, S Suri, et al (2021). “ Effect of an antidiabetic extract of Catharanthus roseus on enzymic activities in streptozotocin induced diabetic rats”, Journal of Ethnopharmacology, 76(3), 269-277.
15. R R Chattopadhyay (1999). “A comparative evaluation of some blood sugar lowering agents of plant origin,” Journal of Ethnopharmacology, 67(3), 367-372.
16. S Pandey, K Gupta K and A K Mukherjee (2007). “Impact of cadmium and lead on Catharanthus roseus– A phytoremediation study,” Journal of Environmental Biology, 28(3), 656-662.
17. R B Meagher (2000). “Phytoremediation of toxic elemental and organic pollutants”, Current Opinion in Plant Biology, 3(2), 153-162
18. J Narayan Mishra and N Kumar Verma (2017). “A brief study on Catharanthus Roseus: A review”, International Journal of Research in Pharmacy and Pharmaceutical Sciences, 2(2), 20-23.
19. S Das and A B Sharangi (2017). “Madagascar periwinkle (Catharanthus roseus L.): Diverse medicinal and therapeutic benefits to humankind,” Journal of Pharmacognosy and Phytochemistry, 6(5), 1695-1701.
20. B.S. Nayak, M. Anderson and L.M. Pinto Pereira (2007). “ Evaluation of wound-healing potential of Catharanthus roseus leaf extract in rats, Fitoterapia,” 78(7-8), 540-544.
21. A. M. Marina, Y. B. Che Man, S. A. H.Nasimah, I. Amin, “ Chemical propertiesof virgin coconut oil.” J. Amer. OilChem. Soc., 2009 86 301-307.
22. Thampan, P.K., Glimpses of coconutindustry in India, CoconutDevelopment Board, Cochin 1988.
23. Baltasar S.F. “ Coconut oil extractionemploying the dry processingtechnology. Phillip. J. Coconut Studies,1977 2 (4) 40-42.
24. Aliwalas A.R., Buccat C.P., “Filtration-extraction of granulated coconut on abench scale”. Phillip. J. Sci., 1970, 96(3) 215-285.
25. Bellenand J.F., Baloutch G., Ong N.;Lecerf J., “Effects of coconut oil on heartlipids and on fatty acid utilization inrapeseed oil.” Lipids, 1980 15 (11) 938-943.
26. Banzon J.A., Resurreccion A.P., “Fattyacid distribution in coconut oil obtainedby four processing methods and securedfrom four Philippine types of coconuts.Phillip”. J. Coconut Studies, 1979 4 (2) 10-18.
27. C-Hua Wang, G-Cai Wang, Y Wang, et al (2012). “Cytotoxic dimeric indole alkaloids from Catharanthus roseus”, Fitoterapia, 83(4), 765-769.
28. J Narayan Mishra and N Kumar Verma (2017). “A brief study on Catharanthus Roseus: “A review, International Journal of Research in Pharmacy and Pharmaceutical Sciences, 2(2), 20-23.
29. Y Patel, V Vadgama, S Baxi, Chandrabhanu and B Tripathi (2011). “Evaluation of hypolipidemic activity of leaf juice of Catharanthus roseus (Linn.) G. Donn. In guinea pigs,” Acta Poloniae Pharmaceutica, 68(6), 927-935,
30. M A Bhutkar and S B Bhise (2011). “Comparative studies on antioxidant properties of Catharanthus rosea and Catharanthus”, International Journal of Pharmaceutical Techniques, 3(3), 1551-1556.
31. Abbasi SP, Abbasi ST, Khoharo K, Talpur HK, Siddiqui SM (2014) “Blood glucose lowering effect of Catharanthus roseus in alloxan induced diabetic rats.”Eur J Mol Biol Biochem 1:63–66.
32. Ahmad NH, Rahim RA, Mat I (2010) “ Catharanthus roseus aqueous extract is cytotoxic to jurkat leukaemic t-cells but induces the proliferation of normal peripheral blood mononuclear cells”. Trop Life Sci Res 21:101–113.
33. Ahmed MF, Rao AS (2013) “ Comparative hepatoprotective activities of selected Indian medicinal plants.” Glob J Med Res Pharma Drug Discov Toxicol Med 13(2):15–21.
34. Akhila A (2007) “Metabolic engineering of biosynthetic pathways leading to isoprenoids: mono- and sesquiterpenes in plastids and cytosol.” J Plant Interact 2:1742–9153.
35. Alaguchamy N, Jayakumararaj R (2015) “Larvicidal effect of Catharanthus roseus L (G) Don. Aqueous extracts on the larvae of Heliocoverpa armigera (Hubner)”. Int J Life Sci Educ Res 3:10–14.
36. Archana H, Vasist R, Sharma RB, Gupta A (2016)” Pharmacological reputation of Vinca plant” World J Pharm Pharm Sci 5:1602–1610.
37. Asha A, Vinita P, Hetal J (2015) “In vivo comparative study of different variants of Catharanthus roseus (L.) G. Don. For free radical scavenging activity in type 2 diabetes mellitus”. J de Afrikana 2:74–86.
38. Aslam J, Mujib A, Sharma MP (2014) “Somatic embryos in Catharanthus roseus: a scanning electron microscopic study”. Natulae Scientia Biologicae 6:167–172.
39. Asthana RB, Misra MK (1979)” Orally effective hypoglycemic agent from Vinca rosea”. Ind J Biochem Biophys 16:30–35.
40. Banakar V, Malagi U, Naik R (2007)” Impact of periwinkle leaves (Catharanthus roseus) on management of diabetes mellitus, Karnataka.” J Agric Sci 20:115–119.
41. Benjamin BD, Kelkar SM, Pote MS (1994) “ Catharanthus roseus cell culture: growth, alkaloid synthesis and antidiabetic activity” Phytother Res 8:185–186.
42. Bhutkar MA, Bhise SB (2011) “Comparative studies on antioxidant properties of Catharanthus roseus and Catharanthus alba”. Int J Pharm Technol Res 3:1551–1556.
43. Daly E.M., Taylor R.E. “Entropy and enthalpy in the activity of tubulin-based antimitotic agents”. Curr. Chem. Biol. 2009;3:47–59.
44. Ganapathi B., Kargi F. “Recent Advances in Indole Alkaloid Production by Catharanthus roseus (Periwinkle)” J. Exp. Bot. 1990;41:259–267.
45. Ramani S., Jayabaskaran “Catharanthus Enhanced catharanthine and vindoline production in suspension cultures of Catharanthus roseus by ultraviolet-B light.”J. Mol. Signal. 2008;3:9–14.
46. Ahmad NH, Rahim RA, Mat I (2010) “Catharanthus roseus aqueous extract is cytotoxic to jurkat leukaemic t-cells but induces the proliferation of normal peripheral blood mononuclear cells.” Trop Life Sci Res 21:101–113.
47. Akhila A (2007) “Metabolic engineering of biosynthetic pathways leading to isoprenoids: mono- and sesquiterpenes in plastids and cytosol. J Plant Interact 2:1742–9153.
48. Amini A, Glevarco G, Andreu F, Rideau M, Creche J (2009) “Low levels of gibberellic acid control the biosynthesis of ajmalicine in Catharanthus roseus cell suspension cultures. “Planta Med 75:187–191.
49. Andrade-Cetto A, Heinrich M (2005) “Mexican plants with hypoglycaemic effect used in the treatment of diabetes.” J Ethnopharmacol 99:325–348.
50. Archana H, Vasist R, Sharma RB, Gupta A (2016)” Pharmacological reputation of Vinca plant.”World J Pharm Pharm Sci 5:1602–1610.
51. Ferrari G, Fervidi O, Ferrari M (1971) Phytochemistry. In: “Arnold B (ed) The alkaloid.”Academic Press, London, pp 24-28.
52. Kumar A, Singhal KC, Sharma RA, Govind K, Kumar VV (2012) “Analysis of antioxidant activity of Catharanthus roseus L. and it’s association with habitat temperature. “Asian J Exp Biol Sci 3:706–713
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Dec 11, 2024
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Utpal Prajapati, Ms. Foram Mehta, & Dr. Pragnesh Patani. (2024). EXPLORING THE SYNERGISTIC EFFECTS OF CATHARANTHUS TRICOPHYLLUS AND COCONUT OIL ON HUMAN HEALTH: A REVIEW OF THE EVIDENCE. Journal of Population Therapeutics and Clinical Pharmacology, 31(11), 1134-1139. https://doi.org/10.53555/ajhz3a68
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Author Biographies
Utpal Prajapati
Student, Khyati College of Pharmacy, Palodia, Ahmedabad
Ms. Foram Mehta
Assistance Professor, Khyati College of Pharmacy, Palodia, Ahmedabad
Dr. Pragnesh Patani
Principal, Khyati College of Pharmacy, Palodia Ahmedabad
How to Cite
Utpal Prajapati, Ms. Foram Mehta, & Dr. Pragnesh Patani. (2024). EXPLORING THE SYNERGISTIC EFFECTS OF CATHARANTHUS TRICOPHYLLUS AND COCONUT OIL ON HUMAN HEALTH: A REVIEW OF THE EVIDENCE. Journal of Population Therapeutics and Clinical Pharmacology, 31(11), 1134-1139. https://doi.org/10.53555/ajhz3a68