"DETECTION OF GRAM-NEGATIVE BACTERIA IN URINARY TRACT INFECTIONS USING ADVANCED MOLECULAR DIAGNOSTICS"

Main Article Content

Nawaf ayd alofi
Ameen Abdulhadi Almuwallad
Saeed Saleh Albalawi
Alaa Ali Algorafi

Keywords

Gram-Negative Bacteria , Urinary Tract Infections , Molecular Diagnostics, polymerase chain reaction

Abstract

The application of molecular diagnostic methods to the detection of Gram-negative bacteria in UTIs is examined in this work. Effective treatment is delayed by the lack of specificity and lengthier turnaround times of traditional diagnostic techniques. Next-generation sequencing (NGS) and polymerase chain reaction (PCR) are used in this study to quickly discover and identify particular Gram-negative infections. Results indicate that molecular diagnostics provide a promising substitute for efficient UTI treatment by improving accuracy and cutting down on diagnosis time.

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References

Reference:
1. Centers for Disease Control and Prevention (CDC) - Information on UTIs and antimicrobial resistance provides background on the importance of accurate and timely diagnosis.
• CDC - Urinary Tract Infection (UTI)
2. Journal of Clinical Microbiology - Studies on molecular diagnostics for UTIs and the use of PCR in detecting Gram-negative bacteria.
•Accessible via PubMed
3. Nature Reviews Microbiology - This journal contains reviews on advancements in molecular diagnostics, including NGS and its applications in infectious disease detection.
• Nature Reviews Microbiology
4. BMC Infectious Diseases - Articles on PCR and NGS applications in infectious disease diagnostics, with specific studies on UTIs and Gram-negative pathogens.