Antibiotic Resistance Patterns in Cirrhotic Patients with Spontaneous Bacterial Peritonitis: A Microbial Spectrum Analysis

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Yousra Rahat, Umaya tehreem, Muhammad Maaz, Pawan Kumar, Waleed rawan, Muhammad Usman Fazal, Faisal Ahmad, Fawad khalid

Keywords

cirrhosis, ascitic fluid, spontaneous bacterial peritonitis, antibiotic sensitivity

Abstract

Objective: Recent studies have highlighted shifts in the microbial composition of ascitic fluid in spontaneous bacterial peritonitis (SBP) and the growing resistance of these bacteria to commonly used antibiotics. This study aimed to identify the microorganisms responsible for SBP and assess their antibiotic sensitivity profiles. The current observational study was done in the department of 
medicine at PIMS hospital Islamabad from March to November 2022. Forty-five cirrhotic patients with ascites were admitted in ward for various reasons and having positive ascitic fluid culture were included in the study. The current study results show that the mean age of these 35 patients was 48.94 ± 13.51 years with a range of 19 to 80 years.

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