ASSESSMENT OF ASYMPTOMATIC URINARY TRACT INFECTIONS IN UROLITHIASIS

Main Article Content

Dr. Shanjeev K.M.
Dr. Roshan V Shetty
Dr. Anokha Jagadish
Dr. Adithya Marla

Keywords

Urolithiasis, Asymptomatic Urinary Tract Infections.

Abstract

BACKGROUND: Genetic, metabolic, environmental, viral, socioeconomic, and nutritional factors are the multifactorial etiopathogenesis of urolithiasis, a disorder marked by the development of stones in the kidney, bladder, ureter or urethra. There is enough evidence that urolithiasis makes a substantial contribution to UTI incidence.


AIMS & OBJECTIVES: To determine the proportion of UTI (symptomatic and asymptomatic), to determine the most typical organism involved in causing Urinary Tract Infections, to determine the antibiotic susceptibility of the organisms causing Urinary Tract Infections, and to study the relationship of type and duration amongst symptomatic and asymptomatic urinary tract infection in patients with urolithiasis.


METHODS: This was a hospital based cross-sectional study of 152 patients, diagnosed radiologically to have urolithiasis who met the inclusion criteria. Clinical History of patients who have been diagnosed to have urolithiasis radiologically (i.e. USG or CT-KUB) was taken. Urine routine and urine culture were done to test for culture and sensitivity.


RESULTS: Compared to the other group, subjects under 40 years old had a low infection rate. Urine cannot move easily when stones and other causes such as BPH, prolapse, stricture, etc., cause urinary tract obstruction which is shown to be a risk factor for UTI. A significant difference was observed in the culture growth of symptomatic males with BPH.


CONCLUSION: In patients with urolithiasis, characteristics such as age, sex, blockage, multiple stone locations, and stone type (like staghorn stones) may be separate causes of UTIs. The most prevalent bacteria in UTIs in urolithiasis patients are gram-negative bacilli.

Abstract 43 | pdf Downloads 27

References

[1] Ohkawa M, Tokunaga S, Nakashima T, Yamaguchi K, Orito M, Hisazumi H. Composition of urinary calculi related to urinary tract infection. J Urol 1992;148(3):995-7.
[2] Sabinski F, Leusmann DB. Potential contribution of optional urease-positive bacteria to idiopathic urinary calcium stone formation. I. Expression of urease activity in bacteria from the urinary tract that are commonly classified as urease-negative. J Urol 1996;24(1):51–4.
[3] Marien T, Mass AY, Shah O. Antimicrobial resistance patterns in cases of obstructive pyelonephritis secondary to stones. Urology 2015;85(1):64–8.
[4] Fernandes DJ, Jaidev M, Castelino DN. Utility of dipstick test (nitrite and leukocyte esterase) and microscopic analysis of urine when compared to culture in the diagnosis of urinary tract infection in children. Int J Contemp Pediatr 2017;5(1):156.
[5] Sagbo GG, Sogbo F, Lalya HF, Agossou J, Tohodjèdé Y, Alihonou F, et al. Contribution of the urine dipstick to urinary tract infection diagnosis among children in two hospitals in Cotonou-Benin. Open Journal of Pediatrics 2017;7(04):272.
[6] Mariappan P, Tolley DA. Endoscopic stone surgery: minimizing the risk of post-operative sepsis. Curr Opin Urol 2005;15(2):101-5.
[7] Marien T, Miller NL. Treatment of the Infected Stone. Urol Clin North Am 2015;42(4):459-72.
[8] Nayak US, Solanki H. Utility of dipstick versus urine culture in diagnosis of urinary tract infection in children. Gujarat Med J 2010;65:20-2.
[9] Taneja N, Chatterjee SS, Singh M, Sivapriya S, Sharma M, Sharma SK. Validity of quantitative unspun urine microscopy, dipstick test leucocyte esterase and nitrite tests in rapidly diagnosing urinary tract infections. JAPI 2010;58:485-7.
[10] Memişoğulları R, Yüksel H, Yıldırım HA, Yavuz Ö. Performance characteristics of dipstick and microscopic urinalysis for diagnosis of urinary tract infection. Eur J Gen Med 2010;7(2):174-8.
[11] Robinson JL, Finlay JC, Lang ME, Bortolussi R. Urinary tract infection in infants and children: Diagnosis and management. Paediatrics & Child Health 2014;19(6):315-9.
[12] Stein R, Dogan HS, Hoebeke P, Kočvara R, Nijman RJ, Radmayr C, et al. Urinary tract infections in children: EAU/ESPU guidelines. European urology. 2015;67(3):546-58.
[13] Fallanzadeh MH, Alamdarbe HM. Prevalence of urinary tract infection in preschool febrile children. Irn J Med Sci 1999;24:35-39.
[14] Shaw KN, Gorelick M, McGowan KL, Yakscoe HM, Schwartz JS. Prevalence of urinary tract infection in febrile young children in the emergency department. Pediatrics 1998;102(2):E16.