CASE REPORT: PERIPARTUM CARDIOMYOPATHY, A RARE BUT FATAL CONDITION IN PREGNANCY AND PUERPERIUM
Main Article Content
Keywords
Peripartum Cardiomyopathy, puerperium, Echocardiogram, Congestive cardiac failure.
Abstract
Peripartum Cardiomyopathy (PPCM) is a rare but potentially deadly heart condition that occurs in previously healthy young women during late pregnancy or shortly after giving birth. It is marked by a weakening of the heart’s left ventricle without any other known heart issues. PPCM has high rates of illness and death, making it one of the leading causes of maternal mortality. Despite significant progress in understanding PPCM over the past few decades, many questions about its underlying causes, diagnosis, and treatment remain unanswered. Although PPCM is rare, it needs quick and careful management. Early detection and timely treatment are crucial in lowering the risk of death for mothers. In this case report a 32-year-old woman, seven days postpartum, presented with acute shortness of breath, chest pain, and fever. Her medical history included smoking, class II obesity, pre-eclampsia, and HELLP syndrome. Clinical examination revealed persistent tachycardia and mild lung crepitation. Imaging and lab results indicated bilateral pulmonary congestion, elevated CRP, and a severely dilated left ventricle with an ejection fraction of 31%. She was diagnosed with congestive cardiac failure and managed with diuretics, beta-blockers, and ACE inhibitors. Post-treatment, the patient improved and was discharged with plans for cardiac MRI and genetic testing. This case is important for the diagnostic challenges of postpartum cardiomyopathy and the long-term follow-up to mitigate chronic heart failure risk.
References
2. Krishnamoorthy P, Garg J, Palaniswamy C, Pandey A, Ahmad H, Frishman WH, et al. Epidemiology and outcomes of peripartum cardiomyopathy in the United States: findings from the Nationwide Inpatient Sample. Journal of Cardiovascular Medicine. 2016;17(10):756-61.
3. Iorgoveanu C, Zaghloul A, Ashwath M. Peripartum cardiomyopathy: a review. Heart Fail Rev. 2021;26(6):1287-96.
4. Ntusi NB, Mayosi BM. Aetiology and risk factors of peripartum cardiomyopathy: a systematic review. International journal of cardiology. 2009;131(2):168-79.
5. Blauwet LA, Cooper LT. Diagnosis and management of peripartum cardiomyopathy. Heart. 2011;97(23):1970-81.
6. Matemvu Z, Likapa H, Makin MS, Hossain O. Five cases of Peripartum Cardiomyopathy in Malawi. Malawi Med J. 2023;35(3):196-200.
7. Hoevelmann J, Engel ME, Muller E, Hohlfeld A, Böhm M, Sliwa K, et al. A global perspective on the management and outcomes of peripartum cardiomyopathy: a systematic review and meta‐analysis. European Journal of Heart Failure. 2022;24(9):1719-36.
8. Bala R, Mehta S, Roy VC, Kaur G, de Marvao A. Peripartum cardiomyopathy: A review. Rev Port Cardiol. 2023;42(11):917-24.
9. Patel H, Berg M, Barasa A, Begley C, Schaufelberger M. Symptoms in women with Peripartum Cardiomyopathy: A mixed method study. Midwifery. 2016;32:14-20.
10. Cho S-H, Leonard SA, Lyndon A, Main EK, Abrams B, Hameed AB, et al. Pre-pregnancy obesity and the risk of peripartum cardiomyopathy. American journal of perinatology. 2021;38(12):1289-96.
11. Lindley KJ, Conner SN, Cahill AG, Novak E, Mann DL. Impact of preeclampsia on clinical and functional outcomes in women with peripartum cardiomyopathy. Circulation: Heart Failure. 2017;10(6):e003797.
12. Carlson S, Schultz J, Ramu B, Davis MB. Peripartum cardiomyopathy: risks diagnosis and management. Journal of Multidisciplinary Healthcare. 2023:1249-58.
13. Honigberg MC, Elkayam U, Rajagopalan N, Modi K, Briller JE, Drazner MH, et al. Electrocardiographic findings in peripartum cardiomyopathy. Clinical cardiology. 2019;42(5):524-9.
14. Kim M-J, Shin M-S. Practical management of peripartum cardiomyopathy. The Korean journal of internal medicine. 2017;32(3):393.
15. Elkayam U. Clinical characteristics of peripartum cardiomyopathy in the United States: diagnosis, prognosis, and management. Journal of the American College of Cardiology. 2011;58(7):659-70.