COMPARATIVE ANALYSIS OF FETOMATERNAL OUTCOMES IN PREGNANT WOMEN WITH THROMBOCYTOPENIA DURING DELIVERY: A ONE-YEAR STUDY AT A TERTIARY CARE HOSPITAL
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Keywords
Thrombocytopenia, Blood Transfusion, Gestational Thrombocytopenia
Abstract
Objective: The present study evaluated fetomaternal outcomes in pregnant females with thrombocytopenia.
Materials and Methods: This comparative study involved pregnant women with and without thrombocytopenia admitted into labour. The study assessed aetiology, maternal morbidities such as intrapartum and postpartum haemorrhage, the need for blood and blood product transfusions, Medical Intensive Care Unit (MICU) admissions, maternal mortality, and neonatal outcomes, including morbidity and mortality rates. Particular attention was paid to the rate of preterm deliveries and NICU admissions in thrombocytopenic patients.
Results: The blood and blood product transfusion requirement were significantly higher in the thrombocytopenia group than in controls. No significant differences were observed between groups in terms of gravid status, mode of delivery, antepartum haemorrhage (APH), postpartum haemorrhage (PPH), APGAR scores, intrauterine growth restriction (IUGR), NICU admissions, or stillbirth rates. Thrombocytopenia was most frequently gestational in origin and did not generally affect maternal or neonatal outcomes. However, in cases where thrombocytopenia was associated with conditions such as preeclampsia or HELLP syndrome, interventions were often necessary. Preterm delivery, NICU admission, and the need for transfusions were more common in the thrombocytopenia group.
Conclusion and Recommendation: A multidisciplinary approach involving obstetricians, medical intensivists, haematologists, and neonatologists ensures favourable maternal and neonatal outcomes in thrombocytopenia cases. Early detection and timely management of thrombocytopenia are key to preventing complications.
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Dr Rahi Modi
Assistant Professor, Department of Obstetrics and Gynecology, B.J. Medical College and Civil Hospital, Ahmedabad, Gujarat, India.
Dr Srushti Patel
Consultant Obstetrician and Gynaecologist, Aayush Hospital, Mehsana, Gujarat, India.
Dr Martina Balat
Assistant Professor, Department of Community Medicine, GMERS Medical College, Himmatnagar, Gujarat, India.
Dr Rinku Mulchandani
Ex registrar Obstetrician and Gynaecologist, KD Hospital, Ahmedabad, Gujarat, India.