PREVALENCE OF ANGIOGRAPHICALLY SIGNIFICANT LEFT MAIN DISEASE AT A TERTIARY CARE HOSPITAL
Main Article Content
Keywords
Prevalence, Angiography, Left Main Disease
Abstract
Background: Coronary artery disease(CAD) is the common cause of mortality and morbidity in the developed world as well as in the developing world. CAD was thought to be the disease of developed world but now its prevalence is increasing in developing countries too even after new advancements in diagnostic and therapeutic procedures due to lifestyle changes and rapid urbanization.
Objective: To determine the prevalence of Angiographically Significant Left Main Disease at a Tertiary Care hospital
Methodology: This retrospective study was carried out at the department of cardiology Sande man provincial hospital Quetta. The current study was carried out from July 2022 to November 2023 after taking ethical review committee approval. All patient had their full blood count, renal function test, liver function test, serum electrolytes, and virology. Patients with a creatinine of more than 2 milligrams per deciliter (mg/dl) and hemoglobin(Hb) less than 10mg/dl were dropped from the study. In all cases, coronary angiography was performed and percutaneous coronary intervention(PCI)was performed if the vessel was suitable for intervention, and coronary artery by pass grafting (CABG)if the syntax score exceeded 32. All the data was analyzed by using SPSS version 24.
Results: In the current study, a total of 3000 patient’s data was selected for the study, during the study duration from July 2022 to November 2023. The frequency of the severe left main coronary artery disease was 100 (3.33%). Of these 100 patients, the male patients in our study were 85 (85%) while female patients were 15 (15%).The mean age of the patients was 58 (8.16) years with minimum age of 28 and maximum age of 92 years. Out of 100 patients with LMS disease, 10(10%) presented with CCS grade I angina, 71 (71%) presented with CCS grade II angina, 15 (15%) presented with CCS grade III angina, and 4 (4%) presented with CCS grade IV angina.
Conclusion: Our study concludes that the frequency of severe left main coronary artery disease is very high. A sovereign risk factor for high mortality and morbidity is left main disease, which is common. Whether the present-day guidelines are enough for angiography in patients with multiple risk factors and stable angina or need redefinition and will be cost-effective is an unanswered question.
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Abdul Ghaffar Khan
Associate Professor Cardiology SPH/BMCH, Quetta
Dost Muhammad Barech
Assistant Professor Cardiology SPH/BMCH, Quetta
Muhammad Assa
Senior Registrar Cardiology SPH/BMCH, Quetta
Fazal Ur Rehman
Associate Professor Cardiology SPH/BMCH, Quetta