A COMPARATIVE STUDY OF PARASITIC AND ROTAVIRUS A GASTROENTERITIS IN CHILDREN BELOW 5 YEARS AT EASTERN UTTAR PRADESH
Main Article Content
Keywords
Diarrhoea, Rotavirus A,, prasites, co-infection
Abstract
Diarrheal diseases continue to be a major concern for developing countries. An estimated 248 million episodes of diarrhea occurs every year in children under 5 years. A diversity wide enough, these diarrheal agents include non-infectious (e.g., toxins) and infectious agents (bacterial, protozoal, and viral). 323 stool samples were collected which were tested for the presence of parasites , Rotavirus antigen through ELISA and Rotavirus A was confirmed through RT-PCR. Among the 231 OPD patients, Rotavirus positive cases were found to be 95 (41.1 %), 31(13.42 %) were infected with parasites and other diarrhoeal cases were 105 (45.45 %).
Of the 92 IPD patients, children infected with Rotavirus A were 48 (52.2 %), 13 (14.13 %) were infected with parasites whereas other diarrhoeal cases were 31 (33.7 %) Co-infection of Rotavirus-A with parasites were found in six patients (4 Giardia , 2 Entamoeba histolytica)
References
2. Elliott, E. J. (2007). Acute gastroenteritis in children. British Medical Journal. 2007;334(7583): 35- 40.
3. Nawaz S., Allen D J, Aladin F, Gallimore C, Iturriza-Gomara, M. Human bocaviruses are not significantly associated with gastroenteritis: results of retesting archive DNA from a case control study in the UK. PLoS One. 2012; 7(7): e41346.
4. Einarsson E, Ma'ayeh, S,Svard S.G. An up-date on Giardia and giardiasis. Journal of General Virology. 2016; 34:47-52.
5. Squire S.A, Ryan U. Cryptosporidium and Giardia in Africa: current and future challenges. Parasites & Vectors. 2017; 10(1):195.
6. Bányai K, Estes MK, Martella V, Parashar UD. Viral gastroenteritis. The Lancet. 2018 Jul;392(10142):175-86.
7. Iturriza-Gomara M, Simpson R, Perault A M, Redpath C, Lorgelly P, Joshi D, et al. (2008). Structured surveillance of infantile gastroenteritis in East Anglia, UK: incidence of infection with common viral gastroenteric pathogens. Epidemiology & Infection. 2008; 136(1): 23-33.
8. Khan MA. Epidemiological studies on gastroenteritis in children in the Bannu district, Khyber Pakhtunkhwa, Pakistan. J Public Health (Berl). 2023 May;31(5):739-46.
9. Kazi AM, Warraich GJ, Qureshi S, Qureshi H, Khan MMA, Zaidi AKM. Sentinel Hospital-Based Surveillance for Assessment of Burden of Rotavirus Gastroenteritis in Children in Pakistan. PLoS ONE. 2014 Oct 8;9(10):e108221.
10. Sreekant P., Jayaprakash T., & Iyenger P. (2020). Seasonal Distribution of diarrhea among children aged 1-5 years in slums of southern India: A cross-sectional door to door survey. International Healthcare Research Journal, 4(6), 158–161.
11. Saha J, Mondal S, Chouhan P, Hussain M, Yang J, Bibi A. Occurrence of Diarrheal Disease among Under-Five Children and Associated Sociodemographic and Household Environmental Factors: An Investigation Based on National Family Health Survey-4 in Rural India. Children. 2022 May 3;9(5):658.
12. Arun P, Krishnasami K, Gunasekeran P, Fathima G, Padmanabhan V. Detection and molecular characterization of uncommon rotavirus group a genotype g12 among hospitalized children in chennai. TurkJPediatr. 2019;61(2):209.
13. Girish Kumar C, Giri S, Chawla-Sarkar M, Gopalkrishna V, Chitambar SD, Ray P, et al. Epidemiology of rotavirus diarrhea among children less than 5 years hospitalized with acute gastroenteritis prior to rotavirus vaccine introduction in India. Vaccine. 2020 Dec;38(51):8154-60.
14. Shariq Wadood Khan , Ismat Rehana , Arvind Kumar Shukla. Understanding the prevalence of intestinal parasitic infections among children under five years at a tertiary care centre. Int J Acad Med Pharm 2024; 6 (1); 899-902