CONCERTED AND SYNCHRONIZED EFFORT TO CURE DIABETES

Abstract

Therapeutic diabetes cannot be achieved while working in a single direction. Moreover, it requires a multifaceted approach involving diet control, use of α glycosidase inhibitors, insulin therapies, use of drugs, and regular exercise. Further, the human insulin gene (INS) is located on chromosome 11p15.5, between the tyrosine hydroxylase and insulin-like growth factor-2 genes. The INS gene contains three exons and two introns, and the final spliced mRNA transcript is 446 bp in length and codes for the preproinsulin  peptide. Glucose is considered the most important stimulant of insulin secretion from the β cell, but amino acids such as arginine also play important roles as physiologic stimulators of insulin secretion. An intact concentration of cC AMP is required for normal functioning of the genetic system to synthesize insulin in β cells of Langerhans.