EVALUATION OF ANTIMICROBIAL POTENTIAL OF ALOE VERA PLANT LEAVES
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Keywords
Aloe vera, Leaf extracts, Methanol, Aqueous, Antimicrobial, Microbial resistance
Abstract
The problem of microbial resistance towards antimicrobial drugs is becoming a major problem for humankind as it leads to the death of millions of people. To tackle this problem, medicinal plants with ethnobotanical importance can be act as a source for the identification of the new drugs. Therefore, in the current study we aimed for phytochemical screening and evaluation of antimicrobial potential of leaf extracts Aloe vera plant. Leaves of A. vera was subjected to successive solvent extraction by continuous hot extraction (Soxhlet) with 50% methanol and double distilled water. Results depicted that 50% methanolic leaf extract of A. vera showed maximum zone of inhibition (ZOI) of 24mm for bacterial strain Staphylococcus aureus and it has also showed maximum ZOI of 18mm for fungal strain Candida albicans. Aqueous leaf extract of A. vera showed maximum ZOI of 16mm against bacterial strain Klebsiella pneumonia and it has also showed maximum ZOI of 13mm against fungal strain Candida albicans. The secondary metabolites like alkaloids, flavonoids, glycosides, steroids, phenolic compounds/tannins were detected in both 50% methanol and aqueous leaf extracts of A. vera. In conclusion, methanolic and aqueous leaf extracts A. vera have been demonstrated to possess antimicrobial activity, and hence they could be exploited in the development of antimicrobial drugs against various pathogenic microorganisms.
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Mamatha N
Assistant Professor, Department of Botany, K. G. F. First Grade College, Oorgaum, K. G. F., Karnataka, India
Dr. Keshamma E
Assistant Professor, Department of Biochemistry, Maharani’s Science College for Women, Palace Road, Bengaluru, Karnataka, India.