OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY VERSUS DYE ANGIOGRAPHY IN POLYPOIDAL CHOROIDAL VASCULOPATHY
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Keywords
Idiopathic polypoidal choroidal vasculopathy (IPCV), choroidal neovascularization (CNV), Branching venous networks (BVNs), pigment epithelial detachments (PED)
Abstract
Optical coherence tomography angiography (OCTA) could be a valid tool to detect polyps and branching vascular network (BVN) in polypoidal choroidal vasculopathy (PCV) and thus allowing the analysis of the type, the morphology, and the extension of BVN in most of the cases.
Purpose - To determine the sensitivity and specificity of OCTA in detecting polyp and especially BVN, compared to fluorescein angiography (FA) and indocyanine green angiography (ICGA).
Methods - It is a prospective observational study. Patients with suspected PCV were recruited and underwent FFA, ICGA, and OCTA (AngioVue, Optovue, Inc.). Sensitivity and specificity of FA, with ICGA, were assessed and compared with OCTA.
Results – Fifty-four eyes were included clinically consecutively. Out of which, forty-three eyes of 36 patients were studied after confirmation by gold standard ICGA investigation . On ICGA ,21 eyes showed polyp and 16 eyes with polyp with BVN and 6 eyes with BVN only .Sensitivity of OCTA was 88% and specificity was 90%. Concordance between FA/ICGA and OCTA was very good for BVN (0.91; range 0.81–1.00).
Conclusions - OCTA showed high sensitivity and specificity for detection of BVN. Concordance between OCTA and gold-standard dye-based techniques was excellent. OCTA may represent a first-line noninvasive method for the diagnosis of BVN in PCV patients.
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Dr.Vibha Pal
MBBS,DOMS,DNB, Narayana Nethralaya ,Bangalore
Dr.Ravinath Goud Marepally
Assistant Professor, SVS Medical College, Mahabubnagar, Telangana
Dr.Jyoti D Garg
MBBS,DNB,Narayana Nethralaya, Bangalore
Dr. M B Thirumalesh
Consultant In Vitreo-Rerina Services Narayana Nethralaya Bangalore
Dr.Naresh Kumar Yadav
Consultant In Vitreo-Retina Services In Narayana Nethralaya,Bangalore