DIAGNOSTIC ACCURACY OF CYTOLOGY IN BRONCHOAL VEOLAR LAVAGE FOR THE DIAGNOSIS OF LUNG CARCINOMA BY TAKING HISTOPATHOLOGY AS GOLD STANDARD IN PATIENTS PRESENTING WITH SUSPECTED PULMONARY NODULE ON CT-SCAN IN TERTIARY CARE HOSPITAL
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Keywords
Bronchoalveolar lavage, Cytology, Pulmonary Nodule, Lung Carcinoma
Abstract
Objective: To determine the diagnostic accuracy of cytology in bronchoalveolar lavage for the diagnosis of carcinoma lung by taking histopathology as gold standard in patients presenting with suspected pulmonary nodule on CT scan at tertiary care hospital, Lahore.
Methodology: A cross-sectional study at Gulab Devi Hospital, Lahore, from February to July 2024 included 65 patients with pulmonary nodules. Using non-probability consecutive sampling, participants aged 20-60 were selected, provided informed consent, and met inclusion criteria. Bronchoalveolar lavage (BAL) findings were compared with histopathology to assess diagnostic accuracy. Data were analyzed with SPSS Version 26, calculating sensitivity, specificity, and other metrics to evaluate BAL's diagnostic performance.
Results: The study comprised 65 patients, with a predominant male population (78.5%) and an average age of 42.03 years. The cytology of bronchoalveolar lavage (BAL) demonstrated a sensitivity of 70.59%, a specificity of 91.67%, a positive predictive value of 75%, a negative predictive value of 89.80%, and an overall diagnostic accuracy of 86.15%.
Conclusion:Bronchoalveolar lavage (BAL) was found to be a highly specific and overall accurate diagnostic tool for assessing lung carcinoma. BAL cytology significantly enhances precise diagnosis, demonstrating acceptable sensitivity and predictive values among patients. These findings underscore its efficacy as a valuable diagnostic tool in clinical settings.
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Dr. Imran Ali
Gulab Devi Hospital, Lahore Resident Trainee MBBS, FCPS (Trainee)
Dr. Kashaf Memon
Liaquat National Hospital, Karachi Resident Trainee MBBS, FCPS (Trainee) kashaf90210@hotmail.com
Dr. Ali Waliullah
Ghulam Mohammad Mahar Medical College Hospital, Sukkur Consultant MBBS, FCPS
Dr. Zaheer Akhtar
Gulab Devi Hospital, Lahore Professor MBBS, FCPS
Dr. Gohar Fatima
Liaquat National Hospital, Karachi Resident Trainee MBBS, FCPS (Trainee)
Dr. Ayesha Akhtar
Dr. Ziauddin Hospital, Karachi Resident Trainee MBBS, FCPS (Trainee)