THE USE OF NASAL STEROID AND ITS POTENTIAL IMPACT ON INTRAOCULAR PRESSURE
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Keywords
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Abstract
Aim - : To evaluate whether short-term nasal steroid therapy is associated with any adverse effects on IOP.
Materials and methods :A prospective study was done in a tertiary care Hospital with 70 patients.
Results : 67.14% (47patients ) showed no change in IOP after short term use of inhalational steroids .
Conclusion :Short-term use of nasal steroids appears to be safe regarding IOP levels.
References
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2. Dreyer EB. Inhaled steroid use and glaucoma. N Engl J Med1993;329(24):1822 .
3. Opatowsky I, Feldman RM, Gross R, Feldm an ST. Intraocular pressure elevation associated with inhalation and nasal corticosteroids Ophthalmology 1995;I02(2):177-9 .
4. Bui CM, Chen H, Shyr Y, Joos KM. Discontinuing nasal steroids might lower intraocular pressure in glaucoma. J Allergy Clin Immunol 2005; 116(5):1042-7 .
5. Fraunfelder FT, Meyer SM. Posterior subcapsular cataracts associated with nasal or inhalation corticosteroids . Am J Ophthalmol 1990;109(4):489-90 .
6. Christos Spiliotopoulos et al . The effect of nasal steroid administration on intraocular pressure. ENT – Ear , Nose and Throat Journal . July 2007 Vol.86. no-7 .
7. Garbe E, LeLorier J, Boivin JF, Suissa S. Inhaled and nasal glucocorticoids and the risks of ocular hypertension or open-angle glaucoma. JAMA 1997;277(9):722-7 .
8. Bross-Soriano D, Hanenberg-Mil ver C, Sch imelmitz-Idi J, et al. Effects of three nasal topical steroids in the intraocular pressure compartment. Otolaryngol Head Neck Surg 2004;130(2):187-91 .
9. Wordinger RJ,Clark AF. Effects of glucocorticoids on the trabecular meshwork: Towards a better understanding of glaucoma. Prog RetinEye Res 1999;18(5):629-67.
10. US Por Drug Information for the Health Care Professional. 12th ed. Rock ville, Md .: United States Pharmacopeial Convention 1992:56-62.