INVESTIGATE THE LATEST SURGICAL TECHNIQUES AND TECHNOLOGIES IN THE TREATMENT OF COLORECTAL CANCER, SUCH AS MINIMALLY INVASIVE PROCEDURES, ROBOTIC SURGERY, AND ORGAN-SPARING APPROACHES.

Main Article Content

Syed Muhammad Shafqatullah
Dr. Komal Khalid
Dr. Atif Iqbal
Dr. Jamshed Bashir
Dr. Syna Pervaiz Singha
Dr. Amir Derick

Keywords

Colorectal cancer, surgical techniques, minimally invasive surgery, robotic surgery, organ-sparing surgery, clinical outcomes, meta-analysis, patient outcomes, oncological safety

Abstract

Background: Colorectal cancer represents a significant global health burden, necessitating ongoing exploration of advanced surgical techniques and technologies to improve patient outcomes. This study aims to investigate the latest surgical approaches, including minimally invasive procedures, robotic surgery, and organ-sparing techniques, in the treatment of colorectal cancer.


Aim: The primary objective of this research is to comprehensively evaluate the efficacy, safety, and potential advantages of contemporary surgical methods for colorectal cancer. Specifically, we seek to determine the clinical outcomes, postoperative recovery, and long-term survival associated with these innovative approaches.


Methods: A systematic review of the literature was conducted, encompassing studies published from 2010 to 2023. Electronic databases, including PubMed, Medline, and Embase, were searched for relevant articles, and the selection criteria included randomized controlled trials, observational studies, and case series reporting on surgical interventions for colorectal cancer. Data extraction and quality assessment were performed in accordance with established guidelines. Statistical analysis was carried out using comprehensive meta-analysis software to synthesize and compare the outcomes of minimally invasive, robotic, and organ-sparing surgical procedures.


Results: Our analysis revealed that minimally invasive procedures, such as laparoscopic and laparoscopy-assisted surgeries, demonstrated shorter hospital stays, reduced postoperative pain, and equivalent oncological outcomes compared to traditional open surgery. Robotic-assisted surgery showcased improved precision and dexterity, enabling more precise tumor resection and enhanced functional outcomes. Organ-sparing approaches, when feasible, exhibited promising results in preserving patient quality of life without compromising oncological safety.


Conclusion: This study highlights the evolution of surgical techniques and technologies in the management of colorectal cancer. Minimally invasive procedures, robotic surgery, and organ-sparing techniques represent valuable options for patients, offering enhanced recovery and comparable oncological outcomes. The choice of surgical approach should be tailored to individual patient characteristics and tumor factors, with a focus on optimizing both short-term and long-term outcomes.

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References

1. Isaic, A., Motofelea, A. C., Costachescu, D., Pop, G. N., Totolici, B., Popovici, D., & Diaconescu, R. G. (2023, August). What Is the Comparative Efficacy of Surgical, Endoscopic, Transanal Resection, and Radiotherapy Modalities in the Treatment of Rectal Cancer?. In Healthcare (Vol. 11, No. 16, p. 2347). MDPI.
2. Evans, K. M., Sahawneh, J. M., & Ferrara, M. (2023). Rectal cancer surgery: is robotic surgery supported by solid evidence?. Annals of Laparoscopic and Endoscopic Surgery, 8.
3. Crafa, F., Vanella, S., Morante, A., Catalano, O. A., Pomykala, K. L., Baiamonte, M., ... & Giaccaglia, V. (2023). Non-exposed endoscopic wall-inversion surgery with one-step nucleic acid amplification for early gastrointestinal tumors: Personal experience and literature review. World Journal of Gastroenterology, 29(24), 3883.
4. Costello, T. (Ed.). (2023). Principles and Practice of Robotic Surgery. Elsevier Health Sciences.
5. Crippa, J., Foppa, C., & Spinelli, A. (2023). From Transanal Total Mesorectal Excision to Transanal Transection with Single-Stapled: Evolution of Transanal Techniques. Digestive Disease Interventions, 7(01), 037-041.
6. Orji, P., Sun, H., Isali, I., Bell, S., Zaorsky, N., Mishra, K., ... & Bukavina, L. (2023). Female sexual function evaluation and intraoperative vaginal reconstruction in bladder cancer. World Journal of Urology, 1-12.
7. Cisternino, A., Capone, L., Rosati, A., Latiano, C., Sebastio, N., Colella, A., & Cretì, G. (2023). New concept in urologic surgery: The total extended genital sparing radical cystectomy in women. Archivio Italiano di Urologia e Andrologia, 95(2).
8. Misuraca, L., Lugnani, F., Brassetti, A., Cacciatore, L., Tedesco, F., Anceschi, U., ... & Simone, G. (2023). Single-Setting 3D MRI/US-Guided Frozen Sectioning and Cryoablation of the Index Lesion: Mid-Term Oncologic and Functional Outcomes from a Pilot Study. Journal of Personalized Medicine, 13(6), 978.
9. Coleman, J. A., Clark, P. E., Bixler, B. R., Buckley, D. I., Chang, S. S., Chou, R., ... & Smith, L. (2023). Diagnosis and Management of Non-Metastatic Upper Tract Urothelial Carcinoma: AUA/SUO Guideline. The Journal of Urology, 209(6), 1071-1081.
10. Lin, Y., Wuping, W., Yuan, Y., & Xing, W. (2023). Background: In China, open surgical approaches for esophageal cancer (EC) can be divided into two techniques, the right-and left-transthoracic esophagectomy. Although there is an increasing number of instances that use the right side, the optimal surgical technique remains unclear. Based in a large cancer center with rich experience of both transthoracic side approaches, this study compared the long-term survival of patients. Methods of optimizing surgical intervention in esophago-gastric cancer, 23.
11. Kahn, J. M., Smits, G. A., Oosterveld, B. J., & van der Steen-Banasik, E. M. (2023, January). How Small Can We Go? Partial Bladder Radiation Therapy and Brachytherapy. In Seminars in Radiation Oncology (Vol. 33, No. 1, pp. 76-81). WB Saunders.
12. Motamedi, M. A. K., Mak, N. T., Brown, C. J., Raval, M. J., Karimuddin, A. A., Giustini, D., & Phang, P. T. (2023). Local versus radical surgery for early rectal cancer with or without neoadjuvant or adjuvant therapy. Cochrane Database of Systematic Reviews, (6).
13. Coleman, J. A., Clark, P. E., Buckley, D. I., Chang, S. S., Chou, R., Hoffman-Censits, J., ... & Smith, L. (2023). Diagnosis and Management of Non-Metastatic Upper Tract Urothelial Carcinoma: AUA/SUO Guideline (2023).
14. Coyle, C., Lavin, V., & Cree, A. (2023). Radiotherapy of Perineal and Pelvic Malignancies. In Perineal Reconstruction: Principles and Practice (pp. 43-57). Cham: Springer International Publishing.
15. Moskvicheva, L. I. (2023). The role of high-intensity focused ultrasound treatment in patients with uterine myoma. Obstetrics and Gynecology, 1, 13-19.
16. Yang, H., Zhang, Z., Zhao, K., Zhang, Y., Yin, X., Zhu, G., ... & Wang, K. (2023). Initial Experience With Extraperitoneal Laparoscopic Radical Cystectomy With Pelvic Organ-Preserving and Orthotopic Neobladder Techniques for Bladder Cancer in Female Patients. Urology, 171, 77-82.
17. Clay, R., Shaunak, R., Raj, S., Light, A., Malde, S., Thurairaja, R., ... & Nair, R. (2023). Oncological and functional outcomes of organ‐preserving cystectomy versus standard radical cystectomy: A systematic review and meta‐analysis. BJUI compass, 4(2), 135-155.
18. Alabousi, M., & Ghai, S. (2023). Magnetic resonance imaging-guided ultrasound ablation for prostate cancer–A contemporary review of performance. Frontiers in Oncology, 12, 1069518.
19. Junker, T., Duus, L. A., Norgaard, B., Rasmussen, B. S., Lund, L., Azawi, N., & Graumann, O. (2023). Impact of Partial Nephrectomy and Percutaneous Cryoablation on Health-related Quality of Life Two Years After Treatment–A prospective Comparative Cohort Study.
20. Kahmke, R., & MMCia, M. S. (2023). Larynx Cancer. Larynx Cancer, An Issue of Otolaryngologic Clinics of North America, E-Book, 56(2), 333.
21. Ellerkamp, V., Schweizer, R., Binder, G., Luithle, T., Schneider, P., Müller, R., & Fuchs, J. Surgery in congenital adrenal hyperplasia in context to § 1631e.
22. SRS, S. R. (2023). Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy.

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