CASE REPORT: METASTATIC MEDULLARY THYROID CANCER PRESENTING IN A YOUNG MALE

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Hassam Ali
Tayyaba Munir
Muhammad Akbar Sultan
Ahmad Rafique
Luqman Ahmad
Humna Shah Nawaz
Shawwal Amjad
Fatima Iqbal

Keywords

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Abstract

Thyroid cancers stand out as the most prevalent among endocrine system malignancies, contributing to about 3.4% of all diagnosed cancers worldwide1. A distinct type within this category is medullary thyroid cancer, originating from parafollicular C cells traced back to neural crest origins. Upon microscopic examination of these cells, a unique amyloid backdrop becomes evident. These tumors have the intriguing ability to generate a range of substances, including calcitonin, carcinoembryonic antigen, serotonin, and chromogranin2. While around 75% of cases arise sporadically, the remaining 25% are tied to familial factors. Sporadic instances can emerge at any age, whereas the hereditary form tends to affect children and young adults, giving the disease a multifaceted demographic3.

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References

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