ASEPTIC SEPARATION AND CHARACTERIZATION OF BACTERIA PRODUCING SECONDARY INFECTION IN CUTANEOUS LEISHMANIASIS LESIONS
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Abstract
Leishmaniasis is a complex parasitic disease, endemic in 98 countries worldwide including Pakistan. Cutaneous leishmaniasis is a devastating illness and the most common kind of leishmaniasis that results in cuts, scrapes, and sores on the skin. Bacterial presence of skin lesions caused by leishmaniasis result in recurrent bacterial infection. This fatal infection impedes wound healing by causing serious localized and systemic skin problems. The data for this study was gathered from the Leishmania diagnostic and treatment unit located at Kuwait Teaching Hospital in Peshawar. Sterile cotton swabs were used to sample 37 ulcerative patients among 150 instances who were contaminated with secondary infections. Bacteria were identified and described using gram staining, morphology, and biochemical testing after samples were processed on nutrient agar medium. The most often identified bacterium in ulcerative lesions was Staphylococcus aureus, accounting for 43% of cases. Neisseria meningitides was the second most prevalent, discovered in 29% of cases. Staphylococcus epidermidis accounted for 13% of cases, while Escherichia coli was present in 8% of cases. Micrococcus luteus and Propionibacterium acne were both detected in one instance, representing 2.7% of cases each. Due to the serious complications caused by secondary bacterial infection in cutaneous leishmaniasis, it is necessary to recommend suitable antibiotics that may be used in conjunction with antileishmanial drugs as a treatment approach for leishmaniasis.
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Abdus Sami
Qurtuba University of Science and Information Technology Dera Ismail Khan
Iqra Parveen
Dow University of Health Sciences, Karachi
Kanwal Saleem
Dow University of Health Sciences, Karachi
Nadir Akhtar
Quaid I Azam University Islamabad.
Usama Khan
Nowshera Medical College
Hamna Hasan
Dow University of Health Sciences, Karachi
Gaytri Devi
Liaquat National Hospital and Medical College Karachi
Fasihul Lisan
Jiangsu University of Science and Technology, China.