CORRELATION OF DIASTOLIC BLOOD PRESSURE WITH HIGH SENSITIVITY C- REACTIVE PROTEIN IN MIDDLE AGED CORONARY HEART DISEASE PATIENTS
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Keywords
Blood pressure, Diastolic, Patients, Biomarkers, Inflammatory
Abstract
Introduction: Coronary heart disease (CHD) remains one of the leading causes of morbidity and mortality worldwide, particularly affecting middle-aged individuals. This study aims to explore the correlation between diastolic blood pressure and high-sensitivity C-reactive protein levels in middle-aged patients with coronary heart disease.
Methodology: This cross-sectional study was conducted at Rashid Latif Medical College, Lahore during June 2023 to January 2024. The study involved a sample of 320 patients diagnosed with CHD, recruited from a cardiology clinic. Patients aged 40-60 years, diagnosed with CHD, and willing to provide informed consent were included in the study. A comprehensive medical history was obtained from each patient, including demographic information, lifestyle factors, and clinical history related to CHD. Blood pressure measurements were taken using a calibrated sphygmomanometer.
Results: The study involved 320 middle-aged patients with coronary heart disease (CHD). The mean diastolic blood pressure (DBP) among the participants was 85.2 ± 10.4 mmHg, while the mean serum high-sensitivity C-reactive protein (hs-CRP) level was 3.8 ± 1.6 mg/L. A Pearson’s correlation analysis was conducted to explore the relationship between DBP and hs-CRP levels. The analysis revealed a moderate positive correlation between DBP and hs-CRP levels (r = 0.45, p < 0.001), suggesting that higher DBP is associated with higher levels of hs-CRP.
Conclusion: There is a significant association between diastolic blood pressure and high-sensitivity C-reactive protein levels in middle-aged patients with coronary heart disease
References
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Dr Sadia Islam
Associate Professor Physiology Department, Rashid Latif Medical College, Lahore
Dr Fida Muhammad
Assistant Professor of Cardiology, Sargodha Medical College/ Dr Faisal Masood Teaching Hospital, Sargodha
Dr Abdul Sadiq
Acting Professor Department of Biochemistry, Jhalawan Medical College, Khuzdar, Balochistan
Dr Bushra Aslam
Assistant Professor, Department of Physiology, Independent Medical College, Faisalabad, Pakistan
Dr Ayesha Khan
Medical Claims Officer at State Life Ins. Corp of Pak. Health and Accident Insurance
Dr Sobia Khan Nabeel
Assistant Professor, Department of Physiology, Baqai Medical University
Noor ul Huda
Ms (Hons)Food Technology Scholar, University of Agriculture, Faisalabad
Maira Arshad
M. Phil Applied Chemistry, Government College University, Faisalabad
Rida Fatima
Senior Lecturer, Superior University, Lahore