AN EXPLORATION OF ASYMPTOMATIC BACTERIURIA IN TYPE 2 DIABETICS WITH EMPHASIS ON THE PRESENCE OF PYURIA
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Keywords
Diabetes, asymptomatic bacteriuria, Pyuria
Abstract
Introduction: Diabetes mellitus (DM) predisposes individuals to infections due to impaired immune function and metabolic abnormalities. ASB, defined as the presence of bacteria in urine without symptoms of urinary tract infection (UTI), poses significant health risks, including progression to symptomatic UTIs or other complications.
Materials and Methods: A cross-sectional study was conducted involving 97 diabetic participants (males=45, females=52) from a general medicine outpatient department. Urine samples were collected under sterile conditions and cultured to identify bacterial growth, with subsequent antibiotic susceptibility testing performed.
Results: The study found a 15.46% prevalence of ASB, with higher rates observed in females (60%) compared to males (40%). Among isolated organisms, Escherichia coli predominated, particularly in females. Associations were observed between ASB prevalence and factors such as HbA1c levels and duration of diabetes, highlighting longer duration and poorer glycemic control as potential risk factors. In the present study, Cotrimoxazole was effective across Gram-positive and Gram-negative isolates, including ESBL No MRSA observed. In the present study, the overall prevalence of pyuria was 27%. Predominantly pyuria was noted among females.
Conclusion: Understanding these dynamics is crucial for tailored management strategies in diabetic care to mitigate the risks associated with ASB and improve overall health outcomes in this vulnerable population.
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Dr. S. Khaja Mohiddin
Assistant Professor, Department of Microbiology, Government Medical College, Kadapa.
Dr. Bathala Naga Sri Latha
Professor& Head, Department of Microbiology, Government Medical College, Kadapa.
Dr. T. Geetanjali
Associate Professor, Department of Microbiology, Government Medical College, Kadapa.
Dr. S.Mohammed Shahid
Assistant Professor, Department of Microbiology, Government Medical College, Kadapa.
Mr. T. Shanmuka Srinivas
Second Year MBBS Student, Government Medical College, Kadapa.