COMPARATIVE EFFECTS OF COMMERCIALLY AVAILABLE ALLOPATHIC AND AYURVEDIC COUGH SYRUPS ON SALIVARY PH AMONG YOUNG ADULTS: A RANDOMIZED CONTROLLED CLINICAL TRIAL.
Main Article Content
Keywords
Cough syrup, Salivary pH, Sugar content, Allopathic cough syrup, Ayurvedic cough syrup, Dental caries
Abstract
BACKGROUND:
Cough syrups, whether herbal or allopathic, are commonly sugar-based acidic liquids. These formulations have the potential to cause dental issues such as erosion of teeth, increased plaque attachment on tooth surfaces, and, subsequently, a higher incidence of dental caries. The aim of the present study is to compare and evaluate the effects of different commercially available cough syrups on the salivary pH of young adults.
AIM AND OBJECTIVES:
The primary goal of this study is to assess and contrast the impact of commercially accessible cough syrups, both those containing sugar and those without, on the salivary pH levels of young adults.
MATERIALS AND METHODS:
In this randomized controlled clinical study, 60 participants were included, either prescribed cough syrups or self-medicating. The total number of 12 cough syrups were divided into 2 groups, Group A and Group B. Group A - sugar containing cough syrup, Group B - Sugar free cough syrup. Saliva samples were collected at four intervals: before consumption, immediately after consumption, and at 10 and 30 minutes post-consumption of the respective cough syrup. Salivary pH levels were assessed using a Vanira LI613 digital pH meter.
RESULTS
After the ingestion of cough syrup across all groups, there was an immediate decrease in salivary pH, followed by a gradual increase at 10- and 30-minute intervals. These changes were statistically significant (p<0.05). The salivary pH in sugar-containing cough syrup groups was lower at all time intervals compared to the sugarfree groups, and the salivary pH variations was dependent on the time factor, and was not influenced by the presence or absence of the sugar in the cough syrup or the medication type i.e. herbal or allopathic.
CONCLUSION:
In order to address potential future complications, it is crucial to increase awareness among the general public, healthcare professionals, and pharmaceutical vendors about the oral health hazards linked to extended use of cough syrup.
References
2. Sánchez-Sánchez E, Fernández-Cerezo FL, Díaz-Jimenez J, Rosety-Rodriguez M, Díaz AJ, Ordonez FJ, Rosety MÁ, Rosety. Consumption of over-the-Counter Drugs: Prevalence and Type of Drugs. Int J Environ Res Public Health. 2021 May 21;18(11):5530.
3. Ray I, Bardhan M, Hasan MM, Sahito AM, Khan E, Patel S, Jani I, Bhatt PK, Sp R, Swed S. Over the counter drugs and self-medication: A worldwide paranoia and a troublesome situation in India during the COVID-19 pandemic. Ann Med Surg (Lond). 2022 Jun;78:103797.
4. Nirmala SV, Popuri VD, Chilamakuri S, Nuvvula S, Veluru S, Minor Babu MS. Oral health concerns with sweetened medicaments: Pediatricians' acuity. J Int Soc Prev Community Dent. 2015 Jan-Feb;5(1):35-9.
5. Dave P. H, Gurunathan D, Vasantharajan M. S. Comparison of pH Levels of the Saliva Before and After the Consumption of Cough Syrups in Children. Biomed Pharmacol J 2018;11(3).
6. Agrawal, Nikita & Shashikiran, N.D. & Vanka, Amit & Thakur, Rupesh & Sandhu, Sardul. (2010). Cariogenic potential of most commonly prescribed liquid oral medicines for children. People’s Journal of Scientific Research. 3. 7-10.
7. Babu KL, Doddamani GM, Naik LR, Jagadeesh KN. Pediatric liquid medicaments - Are they cariogenic? An in vitro study. J Int Soc Prev Community Dent. 2014 May;4(2):108-12.
8. Gupta M, Panda S. Cariogenic Potential of the commonly Prescribed Pediatric Liquid Medicaments in Kingdom of Saudi Arabia: An in vitro Study. J Contemp Dent Pract. 2017 Apr 1;18(4):307-311.
9. Mayo JA, Ritchie JR. Acidogenic potential of "sugar-free" cough drops. Open Dent J. 2009 Mar 6;3:26-30.
10. Gupta P, Gupta N, Pawar AP, Birajdar SS, Natt AS, Singh HP. Role of sugar and sugar substitutes in dental caries: a review. ISRN Dent. 2013 Dec 29;2013:519421.
11. Newbrun E. Sucrose in the dynamics of the carious process. International Dental Journal. 1982;32(1):13–23.
12. Zero DT. Sugars—the arch criminal? Caries Research. 2004;38(3):277–285.
13. Ericsson YI, Jared B, Stjernstrom L. Investigations into the relationship between saliva and dental caries. Acta Odontologica Scandinavica. 1954;11(3-4):179–194.
14. Maguire A, Rugg-Gunn AJ. Medicines in liquid and syrup form used long-term in paediatrics: A survey in the Northern Region of England. Int J Paediatr Dent. 1994;4:93–9.
15. Mackie IC, Hobson P. Factors affecting the availability of sugar-free medicines for children--a survey in the UK. Int J Paediatr Dent. 1993;3:163–7.
16. Mentes A. pH changes in dental plaque after using sugar-free pediatric medicine. J Clin Pediatr Dent. 2001;25:307–12.
17. Bradley M, Kinirons M. A survey of factors influencing the prescribing of sugar-free medicines for children by a group of general medical practitioners in Northern Ireland. Int J Paediatr Dent. 1996;6:261–4.
18. Sunitha S, Prashanth GM, Shanmukhappa, Chandu GN, Subba Reddy VV. An analysis of concentration of sucrose, endogenous pH, and alteration in the plaque pH on consumption of commonly used liquid pediatric medicines. J Indian Soc Pedod Prev Dent. 2009;27:44–8.
19. Bigeard L. The role of medication and sugars in pediatric dental patients. Dent Clin North Am. 2000;44:443–56.
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Dr. Chetan Vinay Deshmuk
MDS, Assistant Professor & Ph.D. Scholar, Department of Public Health Dentistry, JMF’s ACPM Dental College, Dhule, Maharashtra State.
Dr. Vibhuti Dilip Mistry
MDS, Assistant Professor, Department of Periodontology, JMF’s ACPM Dental College, Dhule, Maharashtra State.
Dr. Arun Suresh Dodamani
MDS, Principal, Professor and Head, Department of Public Health Dentistry, JMF’s ACPM Dental College, Dhule, Maharashtra State.
Dr. Mahesh Ravindra Khairnar
MDS, Assistant Professor, Department of Public Health Dentistry, Faculty of Dental Sciences, IMS, Banaras Hindu University, Varanasi.
Dr. Snehal Sakharam Patil
BDS, Postgraduate Student, Department of Public Health Dentistry, JMF’s ACPM Dental College, Dhule, Maharashtra State.
Dr. Priyanka R. Giri
MDS, Assistant Professor, Department of Oral Medicine and Radiology, MGV KBH Dental College and Hospital, Nashik.