“OUTCOMES OF NASAL PRONGS IN INFANTS WITH RESPIRATORY DISTRESS”

Main Article Content

Dr Khurram Soomro
Dr. Shankar Lal
Dr. Abdul Rehman Shaikh
Dr. Vijia Kumar Gemnani
Dr. Saeed Ahmed Shaikh
Dr. Faisal Saifullah Jamro

Keywords

Infants, Nasal Prongs, Outcomes, Respiratory Distress

Abstract

INTRODUCTION: The World Health Organization recommends administering oxygen by nasopharyngeal catheter, nasal catheter, and nasal prongs as an essential therapeutic strategy. Non-invasive respiratory support, such as nasal continuous positive airway pressure (nCPAP), can alleviate respiratory distress.


OBJECTIVE: To determine the outcomes of nasal prongs in infants with respiratory distress.


STUDY DESIGN AND SETTING: A cross-sectional study was conducted at Children's Hospital, SMBB Medical University, Larkana, Pakistan from June 2022 to September 2023.


MATERIALS AND METHODS: All patients who met the inclusion criteria and visited SMBBMU in Larkana were included in the research. Informed permission was obtained after discussing the technique, hazards, and advantages of the study. Using the proper-sized Hudson RCI Infant Nasal Prong CPAP cannula system (sizes 0 and 1), nasal prongs were applied to all newborns in our research. The Hudson Nasal prong CPAP cannula system's appropriate-sized bonnets were covered with rubber bands and pins to directly attach the prongs to the Fisher & Paykel "Bubble" CPAP system (BC151). The prongs were continued for 3 days and outcomes were measured on 3rd day. All the obtained data were put in the proforma and data was analyzed by using SPSS statistical package version 23 software.


RESULTS: The patients' ages varied from one to twelve months, with a median of 5. Of the total number of children, 36 (60%) were female and 24 (40%) were male. The patients' oxygenation levels varied between 93 and 101, with a median of 96.0. Additionally, their oxygen flow rates varied between 1.7 and 3.5 liters per minute, with a median of 2.4, and their respiratory rate ranged from 14 to 28 per minute with a median of 21.0.


CONCLUSION: It may be concluded that an insignificant difference was observed in outcomes of nasal prongs in infants with respiratory distress with age group, gender, and gestational age. Further research is needed to evaluate the statistical significance using a larger sample size, and other parameters across numerous study locations in Pakistan are required to corroborate the current study's findings.

Abstract 78 | PDF Downloads 36

References

1. Satia I, Cusack R, Greene JM, O’Byrne PM, Killian KJ, Johnston N. Prevalence and contribution of respiratory viruses in the community to rates of emergency department visits and hospitalizations with respiratory tract infections, chronic obstructive pulmonary disease and asthma. PloS one. 2020 Feb 6;15(2):e0228544.
2. Reuter S, Moser C, Baack M. Respiratory distress in the newborn. Pediatr Rev. 2014;35 (10):417-28.
3. Rojas-Reyes MX, Granados Rugeles C, Charry-Anzola LP. Oxygen therapy for lower respiratory tract infections in children between 3 months and 15 years of age. Cochrane Database Syst Rev. 2014;2014(12): CD005975.
4. McCarthy LK, Twomey AR, Molloy EJ, Murphy JF, O'Donnell CP. A randomized trial of nasal prong or face mask for respiratory support for preterm newborns. Pediatrics. 2013;132(2):e389-95.
5. ten Brink F, Duke T, Evans J. High-flow nasal prong oxygen therapy or nasopharyngeal continuous positive airway pressure for children with moderate-to-severe respiratory distress. Pediatr Crit Care Med. 2013;14(7):e326-31.
6. Goel S, Mondkar J, Panchal H, Hegde D, Utture A, Manerkar S. Nasal mask versus nasal prongs for delivering nasal continuous positive airway pressure in preterm infants with respiratory distress: a randomized controlled trial. Indian Pediatr. 2015;52(12):1035–40.
7. Chandrasekaran A, Thukral A, Jeeva Sankar M, Agarwal R, Paul VK, Deorari AK. Nasal masks or binasal prongs for delivering continuous positive airway pressure in preterm neonates-a randomised trial. Eur J Pediatr. 2017;176(3):379–86.
8. Guideline: Updates on Paediatric Emergency Triage, Assessment and Treatment: Care of Critically-Ill Children. (2016). Guideline: Updates on Paediatric Emergency Triage, Assessment and Treatment: Care of Critically-Ill Children. World Health Organization. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/27010047.
9. Hansmann A, Morrow BM, Lang HJ. Review of supplemental oxygen and respiratory support for paediatric emergency care in sub-Saharan Africa. Afr J Emerg Med. 2017;7 (Suppl):S10-19.
10. East wood GM, Conel BO, Gardner A, Considine J. Evaluation of nasopharyngeal oxygen, nasal prongs and facemask oxygen therapy devices in adult patients:a randomized crossover trial. Anaesth Intensive Care 2008;36(5):691-4.
11. Muhe L, Degefu H, Worku B, Oljira B, Mulholland EK. Comparison of nasal prongs with nasal catheters in the delivery of oxygen to children with hypoxia. J Trop Pediatr 1998; 44(6):365-8.
12. Weber M, Palmer A, Oparaugo A, Muholland K. Comparison of nasal prongs and nasopharyngeal catheter for the delivery of oxygen in children with hypoxaemia because of a lower respiratory tract infection. J Pediatr 1995;127(3):378-83.
13. Gupta N, Saini SS, Murki S, Kumar P, Deorari A. Continuous positive airway pressure in preterm neonates: an update of current evidence and implications for developing countries. Indian Pediatr 2015;52:319–28.
14. Kandraju H, Murki S, Subramanian S, Gaddam P, Deorari A, Kumar P. Early routine versus late selective surfactant in preterm neonates with respiratory distress syndrome on nasal continuous positive airway pressure: a randomized controlled trial. Neonatology 2013;103:148–54.
15. Rojas MA, Lozano JM, Rojas MX, Laughon M, Bose CL, Rondon MA, et al. Very early surfactant without mandatory ventilation in premature infants treated with early continuous positive airway pressure: a randomized, controlled trial. Pediatrics 2009;123: 137–42.
16. Hough JL, Shearman AD, Jardine LA, Davies MW. Humidified high flow nasal cannulae: current practice in Australasian nurseries, a survey. J Paediatr Child Health 2012;48:106– 13.
17. Kugelman A, Riskin A, Said W, Shoris I, Mor F, Bader D. A randomized pilot study comparing heated humidified high-flow nasal cannulae with NIPPV for RDS. Pediatr Pulmonol 2015;50:576–83.
18. Shin J, Park K, Lee EH, Choi BM. Humidified high flow nasal cannula versus nasal continuous positive airway pressure as an initial respiratory support in preterm infants with respiratory distress: a randomized, controlled non-inferiority trial. J Korean Med Sci 2017;32:650–5.
19. Yoder BA, Stoddard RA, Li M, King J, Dirnberger DR, Abbasi S. Heated, humidified high- flow nasal cannula versus nasal CPAP for respiratory support in neonates. Pediatrics 2013;131:e1482–90.
20. Roberts CT, Manley BJ, Dawson JA, Davis PG: Nursing perceptions of high-flow nasal cannulae treatment for very preterm infants. J Paediatr Child Health 2014;50:806–10.
21. Collins CL, Holberton JR, Barfield C, Davis PG. A randomized controlled trial to compare heated humidified high-flow nasal cannulae with nasal continuous positive airway pressure postextubation in premature infants. J Pediatr 2013;162:949–54.
22. Manley BJ, Owen LS, Doyle LW, Andersen CC, Cartwright DW, Pritchard MA, et al. High- flow nasal cannulae in very preterm infants after extubation. N Engl J Med 2013;369: 1425–33.
23. Polin RA, Sahni R. Newer experience with CPAP. Semin Neonatol. 2002;7:379-89.
24. Pillow JJ, Hillman N, Moss TJ. Bubble continuous positive airway pressure enhances lung volume and gas exchange in preterm lambs. Am J Respir Crit Care Med. 2007;176:63-9.
25. Tapia JL, Urzua S, Bancalari A. Randomized trial of early bubble continuous positive airway pressure for very low birth weight infants. J Pediatr. 2012;161:75-80.
26. Bonner KM, Mainous RO. The nursing care of the infant receiving bubble CPAP therapy. Adv Neonatal Care. 2008;8:78-95.
27. McCoskey L. Nursing care guidelines for the prevention of nasal breakdown in neonates receiving nasal CPAP. Adv Neonatal Care. 2008;8:116-24.
28. Kattwinkel J, Fleming D, Cha CC, Fanaroff AA, Klaus MH. A device for administration of continuous positive airway pressure by the nasal route. Pediatrics. 1973;52:131-4.
29. Kieran EA, Walsh H, O’Donnell CPF. Survey of nasal continuous positive airways pressure (NCPAP) and nasal intermittent positive pressure ventilation (NIPPV) use in Irish newborn nurseries. Arch Dis Child Fetal Neonatal Ed. 2011;96:F156.
30. Kieran EA, Twomey AR, Molloy EJ, Murphy JF, O’Donnell CP. Randomized trial of prongs or mask for nasal continuous positive airway pressure in preterm infants. Pediatrics. 2012;130:1170-6.
31. Chandrasekaran A, Sachdeva A, Sankar MJ, Agarwal R, Deorari AK, Paul VK. Nasal mask versus nasal prongs in the delivery of continuous positive airway pressure in preterm infants – An open label randomized controlled trial. E-PAS. 2014:2936:512.
32. Fischer C, Bertelle V, Hohlfeld J, Forcada-Guex M, Stadelmann-Diaw C, Tolsa JF. Nasal trauma due to continuous positive airway pressure in neonates. Arch Dis Child Fetal Neonatal Ed. 2010;95:F447-51
33. Yong SC, Chen SJ, Boo NY. Incidence of nasal trauma associated with nasal prong versus nasal mask during continuous positive airway pressure treatment in very low birthweight infants: a randomised control study. Arch Dis Child Fetal Neonatal Ed. 2005; 90:480-83.
34. Dani C, Pratesi S, Migliori C, Bertini G. High flow nasal cannula therapy as respiratory support in the preterm infant. Pediatr Pulmonol 2009;44:629-34.
35. Wilkinson D, Andersen C, O’Donnell CP, De Paoli AG, Manley BJ. High flow nasal cannula for respiratory support in preterm infants. Cochrane Database Syst Rev 2016;2: CD006405.
36, Ciuffini F, Pietrasanta C, Lavizzari A, Musumeci S, Gualdi C, Sortino S, et al. Comparison between two different modes of noninvasive ventilatory support in preterm newborn infants with respiratory distress syndrome mild to moderate: preliminary data. Pediatr Med Chir 2014;36: 88.
37. Iranpour R, Sadeghnia A, Abari SS. High flow nasal cannula in the treatment of respiratory distress syndrome in one day-old neonate. Br J Med Med Res 2016;15:1-7.
38. Shin J, Park K, Lee EH, Choi BM. Humidified high flow nasal cannula versus nasal continuous positive airway pressure as an initial respiratory support in preterm infants with respiratory distress: a randomized, controlled non-inferiority trial. J Korean Med Sci. 2017;32(4):650-5.
39. Goel S, Mondkar J, Panchal H, Hegde D, Utture A, Manerkar S. Nasal mask versus nasal prongs for delivering nasal continuous positive airway pressure in preterm infants with respiratory distress: a randomized controlled trial. Indian Pediatr. 2015;52(12):1035-40.
40. Murki S, Singh J, Khant C, Dash SK, Oleti TP, Joy P, et al. High-flow nasal cannula versus nasal continuous positive airway pressure for primary respiratory support in preterm infants with respiratory distress: a randomized controlled trial. Neonatology. 2018;113 (3):235-41

Most read articles by the same author(s)