THE RELATIONSHIP BETWEEN OBESITY AND SERUM ALBUMIN LEVELS IN ADULTS WITHOUT LIVER OR KIDNEY DYSFUNCTION
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Keywords
Hypoalbuminemia, Serum Albumin, BMI, Obesity
Abstract
Objective: The objective of this study is to investigate the potential correlation between blood albumin levels and health complications associated with obesity in persons without any liver or kidney disorders.
Methodology: This study employed a cross-sectional design, using a sample of 160 individuals aged between 25 and 80 years. All participants were of the same gender. The participants were categorized into three distinct categories based on their body mass index (BMI): individuals with a healthy weight, overweight, and obese. Information was obtained regarding the individual's medical history, which may include a diagnosis of type 2 diabetes, physical ailments, and previous substance abuse. Venous blood samples were collected from the patient in order to determine the concentration of serum albumin. The study utilized SPSS 26.0 software to examine the correlation between hypoalbuminemia and obesity.
Results: Our study found no significant differences in the mean ages or gender distribution among normal-weight, overweight, and obese groups, with P-values of 0.125 and 0.172, respectively. While individuals in higher weight categories had a greater likelihood of developing diabetes, this difference was not statistically significant (P = 0.072). However, the prevalence of hypoalbuminemia was significantly higher in the overweight (29.8%) and obese (44.7%) groups compared to the normal-weight group (12.3%), with a P-value of 0.005. Additionally, median serum albumin levels were significantly lower in the overweight and obese groups compared to the normal-weight group (P < 0.001), indicating a strong association between increased body weight and reduced albumin levels.
Conclusion: The study reveals a substantial correlation between low blood albumin levels and being overweight. It is essential to accurately evaluate blood albumin levels in obese individuals to address obesity and provide effective nutrition management. Achieving a comprehensive global consensus on evaluation standards is crucial for these efforts, emphasizing the need for international cooperation and standardized guidelines in managing obesity-related hypoalbuminemia.
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Fida Hussain
MBBS Quaid-e-Azam Medical College, Medical Officer Prince Abdul Kareem Khan Hospital Kalat, Pakistan
Dr Kausar Abbas Saldera
Associate Professor, Department of Physiology, Basic Medical Science Institution, Jinnah Postgraduate Medical Center JPMC Karachi, Pakistan
Dr Rabail Irfan
Medical Doctor, Hayatabad Medical Complex Peshawar, Pakistan
Dr Ammara Naeem
Medical Officer, Ameer-Ud-Din Medical College, Pakistan
Dr Abdullah Zia
House Officer, Department of Internal Medicine, Lahore General Hospital, Pakistan
Dr Muhammad Haider Ali
Resident Doctor, Hayatabad Medical Complex Peshawar, Pakistan
Muhammad Shahroz Khan
Medical Officer, Obaid Noor Hospital, Mianwali, Pakistan
Fahad Asim
Lecturer in Pharmacology & Therapeutics, Faculty of Pharmacy, The University of Lahore, Lahore, Pakistan