A STUDY ON ASSOCIATION BETWEEN ANTI-THYROID ANTIBODIES (ANTI TPO/TG) IN NEWLY DETECTED HYPOTHYROID PATIENTS.
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Keywords
Anti TPO antibody, Hypothyroidism, Anti TG antibody, Autoimmune thyroid disease
Abstract
Background:Hypothyroidism is one of the most common endocrine disorders in India. The most common cause for hypothyroidism is Iodine deficiency. Second most frequent cause is the autoimmune thyroid disease characterized by elevated TPO antibodies and Thyroglobulin (TG) antibodies;However, these autoantibodies are commonly present in the general population as well. Hence, this study is to make a comparison in Anti TPO and Anti TG antibodies in hypothyroid patients in a healthcare set up, which may help in the prognosis and early treatment of the disease. Methods:30 newly detected hypothyroidism patients aged between 18 years to 65 years were randomly selected. A detailed medical history was obtained, and general physical, systemic examination was carried out with prior consent. All the necessary investigations were done, and the results were statistically analyzed.
Results:Anti TPO antibody was positive in 30% of the subjects i.e. autoimmune hypothyroidism was prevalent in 30% of the subjects. Anti TG antibody was found in only 10% of the subjects. Conclusion: Overall association between thyroid antibody and hypothyroidism was assessed. Anti TPO antibody has strong association with autoimmune hypothyroidism compared to anti TG antibody.
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Dr.Pooja pilla
MD, Consultant physician, Apollo Speciality Hospital, Jayanagara, Bangalore
Dr Jagadeesha CG
Associate professor, Department of general medicine, Adichunchanagiri institute of medical sciences, Bellur, Mandya District, Karnataka, India