EVALUATE AND ANALYZE OF TRACE ELEMENTS IN TYPE 2 DIABETES MELLITUS
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Keywords
Diabetes Mellitus, zinc, copper, selenium, Iron
Abstract
Background: As Diabetes Mellitus is a metabolic disorder, where metabolism of various trace elements is being altered. Present study has been carried out to find out the association between Diabetes Mellitus and alteration in the level of trace elements.
Aim: To analyse the level of trace elements in type 2 DM patients in comparison with healthy controls.
Materials and Methods: The present cross sectional study was carried out in 122 patient of Type 2 Diabetes Mellitus. The study was carried out in Clinical biochemistry, central Laboratory, IMCH and RC, Department of Biochemistry, Indore. FBS was estimated by GOD-POD method. Serum Copper and Serum Zinc levels were assessed colorimetrically.
Results: In our study, serum copper level was found high in Type 2 DM patients and serum Zinc level is decrease ed in the patients of Type 2 DM.
Conclusion: Alteration in levels of Copper and Zinc are found to be important predisposing factors for patients of diabetes mellitus for developing complications. From the present study it may be concluded that alteration in levels of trace elements like Cu and Zn may have a role in the pathogenesis and progression of Diabetes Mellitus.
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Harjeet Singh
Tutor, Dept. of Biochemistry, GMC, Ambedkar Nagar (UP)
Dr Jaya Jain
Professor Dept. of Biochemistry, Index Medical College Hospital and Research Centre , Indore, MP
Dr Ashutosh Jain
Assistant Professor Dept, of Physiology, Index Medical College Hospital and Research Centre , Indore, MP
Dr Chaudhary Devendra
Assistant Professor, Dept. of Microbiology, Rajshree Medical Research Institute & Hospital, Bareilly, UP