MENTAL HEALTH IMPLICATION OF POLYCYSTIC OVARY SYNDROME (PCOS); A CROSS-SECTIONAL STUDY

Main Article Content

Fatima
Izaz Jamal
Muhammad Muslim Khan
Ejaz Gul
Hemasa Gul
Sabir Zaman

Keywords

Polycystic ovary syndrome, Mental Health, Women's Health

Abstract

Background: Polycystic ovary syndrome (PCOS) is a hormonal disorder in women that occurs in women of childbearing age and it is estimated that 6-10% of women in the global population suffer from this disease. While many individuals are aware that PCOS has physical symptoms, including delayed or absent periods and excessive hair growth, as well as struggles with conception, the mental effects are not a topic of frequent conversation.


Objective: The objective of this study is to examine the psychological consequences of PCOS in particular on Anxiety, depression, and quality of life of the affected women.


Study Design: A Cross-Sectional Study.


Duration and Place of the Study: Department of Psychiatry & GYNAE & OBS Mardan Medical Complex (MMC) Mardan, between the period of 10th Jan 2020 to 10th July 2021.


Methods: This study involved 105 women with PCOS. Participants were assessed using standardized questionnaires: The BDI is used to assess depression, GAD-7 for anxiety, and WHOQOL-BREF for quality of life.


Results: In this study, the participants are 105 female patients. A high level of depressive symptoms was identified, with 58% of the students being classified as moderate to severe, according to the BDI. Participants also reported high levels of anxiety, with 65% of the participants having a GAD-7 scale score suggestive of moderate to severe anxiety. The overall self-perceived health status declined significantly, although the change was more profound in the QOL dimensions perceived by the patients, especially in psychological aspects and social contacts.


Conclusion: The findings of the current study point to the fact that women with PCOS exhibit high levels of mental health issues. This high prevalence of anxiety and depression in such patients should perhaps explain why an integrated PCOS care delivery model that responds to both body and mind is relevant.

Abstract 62 | Pdf Downloads 26

References

1. Carmina, E., & Lobo, R. A. (1999). Polycystic ovary syndrome (PCOS): arguably the most common endocrinopathy is associated with significant morbidity in women. The Journal of Clinical Endocrinology & Metabolism, 84(6), 1897-1899. DOI: 10.1210/jcem.84.6.5782.
2. Azziz, R., Woods, K. S., Reyna, R., Key, T. J., Knochenhauer, E. S., & Yildiz, B. O. (2004). The prevalence and features of polycystic ovary syndrome in an unselected population. The Journal of Clinical Endocrinology & Metabolism, 89(6), 2745-2749. DOI: 10.1210/jc.2003-032046.
3. Hahn, S., Janssen, O. E., Tan, S., Pleger, K., Mann, K., & Schedlowski, M. (2005). Clinical and psychological correlates of quality-of-life in polycystic ovary syndrome. European Journal of Endocrinology, 153(6), 853-860. DOI: 10.1530/eje.1.02024.
4. Bazarganipour, F., Ziaei, S., Montazeri, A., Foroozanfard, F., Kazemnejad, A., & Faghihzadeh, S. (2013). Health-related quality of life and its relationship with clinical symptoms among Iranian patients with polycystic ovarian syndrome. Iranian Journal of Reproductive Medicine, 11(5), 371-378. DOI: 10.1016/j.rbmo.2013.08.012.
5. Cooney, L. G., Lee, I., Sammel, M. D., Dokras, A. (2017). High prevalence of moderate and severe depressive and anxiety symptoms in polycystic ovary syndrome: a systematic review and meta-analysis. Human Reproduction, 32(5), 1075-1091. DOI: 10.1093/humrep/dex044.
6. Williams, S., Sheffield, D., & Knibb, R. C. (2015). A snapshot of the lives of women with polycystic ovary syndrome: A photovoice investigation. Journal of Health Psychology, 20(3), 339-350. DOI: 10.1177/1359105313509936.
7. DiMatteo, M. R., Lepper, H. S., & Croghan, T. W. (2000). Depression is a risk factor for noncompliance with medical treatment: meta-analysis of the effects of anxiety and depression on patient adherence. Archives of Internal Medicine, 160(14), 2101-2107. DOI: 10.1001/archinte.160.14.2101.
8. Moussavi, S., Chatterji, S., Verdes, E., Tandon, A., Patel, V., & Ustun, B. (2007). Depression, chronic diseases, and decrements in health: results from the World Health Surveys. The Lancet, 370(9590), 851-858. DOI: 10.1016/S0140-6736(07)61415-9.
9. Bazarganipour, F., Ziaei, S., Montazeri, A., Foroozanfard, F., Kazemnejad, A., & Faghihzadeh, S. (2013). Health-related quality of life and its relationship with clinical symptoms among Iranian patients with polycystic ovarian syndrome. Iranian Journal of Reproductive Medicine, 11(5), 371-378. DOI: 10.1016/j.rbmo.2013.08.012.
10. Cooney, L. G., Lee, I., Sammel, M. D., & Dokras, A. (2017). High prevalence of moderate and severe depressive and anxiety symptoms in polycystic ovary syndrome: a systematic review and meta-analysis. Human Reproduction, 32(5), 1075-1091. DOI: 10.1093/humrep/dex044.
11. Jones, G. L., Hall, J. M., Balen, A. H., & Ledger, W. L. (2008). Health-related quality of life measurement in women with polycystic ovary syndrome: A systematic review. Human Reproduction Update, 14(1), 15-25. DOI: 10.1093/humupd/dmm020.
12. Benson, S., Hahn, S., Tan, S., Mann, K., Janssen, O. E., Schedlowski, M., ... & Arck, P. C. (2009). Prevalence and implications of anxiety in polycystic ovary syndrome: results of an internet-based survey in Germany. Human Reproduction, 24(6), 1446-1451. DOI: 10.1093/humrep/dep031.
13. Deeks, A. A., Gibson-Helm, M. E., Paul, E., & Teede, H. J. (2011). Is having polycystic ovary syndrome a predictor of poor psychological function including anxiety and depression? Human Reproduction, 26(6), 1399-1407. DOI: 10.1093/humrep/der071.
14. Moran, L. J., Ranasinha, S., Zoungas, S., McNaughton, S. A., Brown, W. J., & Teede, H. J. (2010). The contribution of diet, physical activity and sedentary behavior to metabolic health in women with polycystic ovary syndrome. BMC Endocrine Disorders, 10(1), 15. DOI: 10.1186/1472-6823-10-15.
15. Dokras, A., Clifton, S., Futterweit, W., & Wild, R. (2011). Increased prevalence of anxiety symptoms in women with polycystic ovary syndrome: systematic review and meta-analysis. Fertility and Sterility, 97(1), 225-230. DOI: 10.1016/j.fertnstert.2011.10.022.