DIAGNOSTIC EFFICACY OF OPEN VS PERCUTANEOUS CORE NEEDLE BIOPSY FOR MUSCULOSKELETAL MALIGNANCIES
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Keywords
Accurate diagnosis, Musculoskeletal sarcoma, Close needle biopsy
Abstract
Background: A simple yet vital procedure in determining the cause of musculoskeletal lesions is the biopsy. Closed needle biopsy (CNB) is a widely used alternative to open incisional biopsy, which has historically been considered the gold-standard procedure due to its high diagnostic accuracy. CNB can be performed under local anaesthesia at an outpatient clinic or in conjunction with image guidance. The current research compares CNB to open incisional biopsy for the goal of examining the diagnosis reliability for muscles and joints sarcoma patients in an outpatient clinic without the application of real-time image guidance.
Material and Method: This study was conducted from January 2021 to December 2021 at the Department of Orthopedics, Hayatabad Medical Complex, Peshawar. A total of 200 individuals with musculoskeletal sarcoma (soft tissue sarcoma or bone sarcoma were included. Circumstances of CNB with unexplained excision, returning sarcoma, and image-guided procedures (fluoroscopy, ultrasound imaging, CT) were not included
Results: The open incisional biopsy demonstrated 97.14% of the diagnostic accuracy for nature, 89.52% for a particular diagnosis, 89.52% for histological type, and 88.57% for histological stage. In contrast, the CNB demonstrated 96.84%, 89.47%, 88.42%, and 86.32% diagnostic accuracy, respectively. In every histological feature, there was no statistically significant distinction among the two approaches (p-value>0.05). For open incisional a biopsy, the diagnostic scores were 98.13% and 97.94% for CNB, accordingly, and there was no significant difference (p-value >0.05). Six instances (3%) had serious mistakes overall; three cases (2.86%) involved open incisional biopsies; and 3 cases (3.16%) involved CNB. Nine (8.57%) via open incisional biopsy, nine (9.47%) from CNB, and eighteen cases (nine per cent) to minor mistakes were reported. Neither technique has any complications linked to biopsies.
Conclusion: when compared to open incisional biopsies, CNB assessment of musculoskeletal sarcoma may obtain a respectably high diagnostic accuracy rate.
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Waseem Ahmad
Training Medical Officer, Department of Orthopedics Surgery, Hayatabad Medical Complex, Peshawar, Pakistan
Nadia Sultana
Training Medical Officer, Department of Medicine, Khyber Teaching Hospital, Peshawar, Pakistan
Asim Naeem
District Specialist, Department of Orthopedics Surgery, DHQ Hospital, Mardan, Pakistan
Rahila Qayyum
Associate Professor, PhD Scholar, Qurtaba University, D.I Khan, Pakistan
Sara Bushra Qayyum
Medical Officer, Gynae & Obs, BHU, Mardan, Pakistan