ROLE OF PERCUTANEOUS CT-GUIDED NEEDLE BIOPSY (PCNB) OF LUNG MASSES WITH IMAGING FEATURES AND HISTOLOGICAL CORRELATION
Main Article Content
Keywords
Biopsy, Computed tomography, Interventional radiology, Lung, Histopathology
Abstract
BACKGROUND
- CT guided percutaneous needle biopsy of the lung is an indispensable tool in the evaluation of pulmonary abnormalities due to high diagnostic accuracy in the detection of malignancy.
- Percutaneous biopsy in the lung plays a critical role in obtaining pathologic proof of malignancy, guiding, staging and planning treatment.
MATERIAL AND METHODS
- The study carried out is hospital based observational study in which 50 patients of all age group from 1st June to 31st December 2023 who were referred to the Department of Radiology in GCRI for further management were included in the study.
- Imaging features of the lung masses were studied and reviewed with the literature. Histological examination was followed up and correlated with the imaging features of CT.
RESULTS:
- The study group was predominantly male (80 %) with highest incidence of lung masses in 51-60 years age group (40 %). Adenocarcinoma was most commonly affected (42 % of cases). CT findings included pleural effusion being most common pathology associated with lung masses.
CONCLUSION
- Percutaneous CT guided biopsy is an effective highly accurate and safe method of obtaining tissue for the diagnosis of indeterminate pulmonary lesions.
References
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8. 3. Aktaş A.R., Gözlek E., Yılmaz Ö., Kayan M., Ünlü N., Demirtaş H., Değirmenci B., Kara M. CT-guided transthoracic biopsy: Histopathologic results and complication rates. Diagn. Interv. Radiol. 2015;21:67–70. doi: 10.5152/dir.2014.140140.
9. 4. Najafi A., Al Ahmar M., Bonnet B., Delpla A., Kobe A., Madani K., Roux C., Deschamps F., de Baère T., Tselikas L. The PEARL Approach for CT-guided Lung Biopsy: Assessment of Complication Rate. Radiology. 2021;2:210360. doi: 10.1148/radiol.2021210360.
10. 5. Manhire A., Charig M., Clelland C., Gleeson F., Miller R., Moss H., Pointon K., Richardson C., Sawicka E. Guidelines for radiologically guided lung biopsy. Thorax. 2003;58:920–936. doi: 10.1136/thorax.58.11.920.
2. Tsukada H, Satou T, Iwashima A, Souma T. Diagnostic accuracy of CT-guided automated needle biopsy of lung nodules. AJR Am J Roentgenol 2000;175(1) 239–243.
3. Priola AM, Priola SM, Cataldi A, et al. Accuracy of CT-guided transthoracic nee-dle biopsy of lung lesions: factors affecting diagnostic yield. Radiol Med (Torino) 2007;112(8):1142–1159.
4. Schreiber G, McCrory DC. Performance characteristics of different modalities for diagnosis of suspected lung cancer: summary of published evidence. Chest 2003 123(1 Suppl):115S–128S.
5. Choi JW, Park CM, Goo JM, et al. C-arm cone-beam CT-guided percutaneous trans-thoracic needle biopsy of small(20 mm) lung nodules: diagnostic accuracy and complications in 161 patients. AJR Am J Roentgenol 2012;199(3):W322–W330.
6. Dempsey P.J., Ridge C.A., Solomon S.B. Advances in Interventional Oncology: Lung Cancer. Cancer J. 2016;22:393–400. doi: 10.1097/PPO.0000000000000229.
7. 2. Heerink W.J., de Bock G.H., de Jonge G.J., Groen H.J., Vliegenthart R., Oudkerk M. Complication rates of CT-guided transthoracic lung biopsy: Meta-analysis. Eur. Radiol. 2017;27:138–148. doi: 10.1007/s00330-016-4357-8.
8. 3. Aktaş A.R., Gözlek E., Yılmaz Ö., Kayan M., Ünlü N., Demirtaş H., Değirmenci B., Kara M. CT-guided transthoracic biopsy: Histopathologic results and complication rates. Diagn. Interv. Radiol. 2015;21:67–70. doi: 10.5152/dir.2014.140140.
9. 4. Najafi A., Al Ahmar M., Bonnet B., Delpla A., Kobe A., Madani K., Roux C., Deschamps F., de Baère T., Tselikas L. The PEARL Approach for CT-guided Lung Biopsy: Assessment of Complication Rate. Radiology. 2021;2:210360. doi: 10.1148/radiol.2021210360.
10. 5. Manhire A., Charig M., Clelland C., Gleeson F., Miller R., Moss H., Pointon K., Richardson C., Sawicka E. Guidelines for radiologically guided lung biopsy. Thorax. 2003;58:920–936. doi: 10.1136/thorax.58.11.920.
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Published
Jun 11, 2024
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How to Cite
Dr Saumil desai, Dr Viraj shah, & Dr Alpesh kalsariya. (2024). ROLE OF PERCUTANEOUS CT-GUIDED NEEDLE BIOPSY (PCNB) OF LUNG MASSES WITH IMAGING FEATURES AND HISTOLOGICAL CORRELATION. Journal of Population Therapeutics and Clinical Pharmacology, 31(6), 1005-1013. https://doi.org/10.53555/jptcp.v31i6.6600
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Author Biographies
Dr Saumil desai
Associate professor, Gujarat cancer & research institute, Gujrat, India
Dr Viraj shah
senior resident, junior resident,Gujarat cancer & research institute, Gujrat, India
Dr Alpesh kalsariya
senior resident, junior resident,Gujarat cancer & research institute, Gujrat, India
How to Cite
Dr Saumil desai, Dr Viraj shah, & Dr Alpesh kalsariya. (2024). ROLE OF PERCUTANEOUS CT-GUIDED NEEDLE BIOPSY (PCNB) OF LUNG MASSES WITH IMAGING FEATURES AND HISTOLOGICAL CORRELATION. Journal of Population Therapeutics and Clinical Pharmacology, 31(6), 1005-1013. https://doi.org/10.53555/jptcp.v31i6.6600