THE SURVIVAL OUTCOME OF PAEDIATRIC EWING SARCOMA, A SINGLE CENTRE STUDY.
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Keywords
Ewing sarcoma, primitive neuroectodermal tumor, pediatric oncology
Abstract
Purpose of the Study: This study aims to evaluate the survival outcomes of children diagnosed with Ewing sarcoma (ES) and primitive neuroectodermal tumor (PNET).
Place of the Study: This retrospective, single-center study included 65 pediatric patients from CMH Rawalpindi from January 2023 to December 2023.
Methods and Materials: This retrospective, single-center study included 65 pediatric patients diagnosed with ES or PNET from January 2023 to December 2023. Data were collected from patient medical records.
Results: The study population consisted of 67.1% males and 32.9% females, with ages ranging from 2 months to 18 years. The highest incidence of ES was observed in males aged 6-10 years. The primary tumor sites included the chest (14.3%), pelvis (9.5%), and tibia (9.5%). Treatment responses varied, with 38.1% of patients showing tumor regression, while 14.3% had stable disease, and 19% of patients were deceased. Adverse effects included febrile neutropenia (19%), cardiogenic shock (9.5%), and fungal pneumonia (9.5%).
Conclusion: The demographic and clinical data from this study highlight the predominance of male patients and the higher incidence of ES in children aged 6-10 years. The primary tumor locations were diverse, emphasizing the need for tailored diagnostic and therapeutic strategies. These findings underscore the importance of supportive care and the need for further research to optimize treatment protocols and improve survival rates.
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Benish Hira
Registrar Peads Oncology CMH Rawalpindi
Tariq Ghafoor
Professor, Armed Forces Bone Marrow Transplant Centre Rawalpindi
Abdul Wahab Siddique
Registrar Peads Oncology CMH Rawalpindi
Awais Arshed
Assistant professor Peads Oncology CMH Rawalpindi
Shaista Naz
Registrar Peads Oncology CMH Rawalpindi
Hashim Khan
Registrar Armed forces and bone marrow transplant center