MICROSURGICAL ANATOMY OF THE CRANIAL NERVES IMPLICATIONS FOR NEUROSURGICAL APPROACHES AND PROCEDURES
Main Article Content
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Abstract
Introduction: The intricate microsurgical anatomy of the cranial nerves plays a pivotal job in guiding neurosurgical approaches and procedures within the complicated landscape of the cranial cavity.
Objectives: The main objective of the study is to find the microsurgical anatomy of the cranial nerves and its implications for neurosurgical approaches and procedures.
Methodology of the study: This prospective observational study was conducted at General hospital, Lahore from March 2023 to January 2024. Data were collected from 80 patients. Patients of varying ages and demographics with diverse pathologies affecting the cranial nerves were included in the study. Clinical data, radiological imaging studies, intraoperative photographs, and surgical records were retrospectively reviewed for each patient. Information regarding the specific cranial nerves involved, anatomical variations, pathological conditions, surgical approaches employed, intraoperative findings, and postoperative outcomes were extracted from medical records.
Results: Data were collected from 80 patients according to inclusion criteria of the study. Mean age of the patients was 58.01±12.5 years and out of 80 patients there were 44 (55%) male patients. Tumors were present in 48 (60%) patients.The trigeminal nerve (CN V) was most commonly affected, accounting for 30% of cases, followed by the facial nerve (CN VII) at 25% and the vestibulocochlear nerve (CN VIII) at 20%. Notably, multiple nerve involvement was observed in 15% of cases, indicating the complexity and multifaceted nature of cranial nerve pathologies encountered in neurosurgical practice.
Conclusion: It is concluded that understanding of microsurgical anatomy is paramount in guiding neurosurgical approaches for cranial nerve-related pathologies. Tailored surgical interventions, informed by intricate anatomical considerations, yield favorable postoperative outcomes while mitigating the risk of iatrogenic complications.
References
2. Sonne J, Lopez-Ojeda W. Neuroanatomy, Cranial Nerve. [Updated 2022 Dec 9]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK470353/
3. López-Elizalde R, Campero A, Sánchez-Delgadillo T, Lemus-Rodríguez Y, López-González MI, Godínez-Rubí M. Anatomy of the olfactory nerve: A comprehensive review with cadaveric dissection. Clin Anat. 2018 Jan;31(1):109-117.
4. Milardi D, Cacciola A, Calamuneri A, Ghilardi MF, Caminiti F, Cascio F, Andronaco V, Anastasi G, Mormina E, Arrigo A, Bruschetta D, Quartarone A. The Olfactory System Revealed: Non-Invasive Mapping by using Constrained Spherical Deconvolution Tractography in Healthy Humans. Front Neuroanat. 2017;11:32.
5. Yoo YJ, Hwang JM, Yang HK. Differences in pupillary light reflex between optic neuritis and ischemic optic neuropathy. PLoS One. 2017;12(10):e0186741.
6. Rosahl S, Bohr C, Lell M, Hamm K, Iro H. Diagnostics and therapy of vestibular schwannomas - an interdisciplinary challenge. GMS Curr Top Otorhinolaryngol Head Neck Surg. 2017;16:Doc03.
7. Tayebi Meybodi, A., Lawton, M. T., Liu, J. K., Preul, M. C., & Sun, H. (2023). Comprehensive microsurgical anatomy of the middle cranial fossa: Part I—Osseous and meningeal anatomy. Frontiers in Surgery, 10, 1132774. https://doi.org/10.3389/fsurg.2023.1132774
8. Lockwood J, Mathkour M, Nerva JD, Iwanaga J, Bui CJ, Vale FL, et al. Anatomic study quantifying the relationship between the arcuate eminence and the root of the zygoma: application to skull base surgery. World Neurosurg. (2021) 146:e773–8. doi: 10.1016/j.wneu.2020.11.014
9. Guo X, Tabani H, Griswold D, Tayebi Meybodi A, Gonzalez Sanchez JJ, Lawton MT, et al. Hearing preservation during anterior petrosectomy: the “cochlear safety line”. World Neurosurg. (2017) 99:618–22. doi: 10.1016/j.wneu.2016.11.019
10. Tayebi Meybodi A, Moreira LB, Lawton MT, Eschbacher JM, Belykh EG, Felicella MM, et al. Interdural course of the ophthalmic artery in the optic canal. J Neurosurg. (2019) 132(1):277–83. doi: 10.3171/2018.6.JNS18856
11. Meybodi, A. T., Mignucci-Jiménez, G., Lawton, M. T., Liu, J. K., Preul, M. C., & Sun, H. (2023). Comprehensive microsurgical anatomy of the middle cranial fossa: Part II—Neurovascular anatomy. Frontiers in Surgery, 10. https://doi.org/10.3389/fsurg.2023.1132784
12. Martinez Pascual P, Maranillo E, Vazquez T, Simon de Blas C, Lasso JM, Sanudo JR. Extracranial course of the facial nerve revisited. Anat Rec. (2019) 302(4):599–608. 10.1002/ar.23825
13. Liu JK. Extended middle fossa approach with anterior petrosectomy for resection of upper petroclival meningioma involving Meckel’s cave: operative video and technical nuances. Neurosurg Focus. (2017) 43(Videosuppl 2):V8. 10.3171/2017.10.FocusVid.17345
14. Chibbaro S, Ganau M, Scibilia A, Todeschi J, Zaed I, Bozzi MT, et al. Endoscopic transorbital approaches to anterior and middle cranial fossa: exploring the potentialities of a modified lateral retrocanthal approach. World Neurosurg. (2021) 150:e74–80. 10.1016/j.wneu.2021.02.095
15. Guizzardi G, Mosteiro A, Hoyos J, Ferres A, Topczewski T, Reyes L, et al. Endoscopic transorbital approach to the middle fossa: qualitative and quantitative anatomic study. OperNeurosurg. (2022) 23(4):e267–75. 10.1227/ons.0000000000000308
16. Plou, P., Serioli, S., Leonel, L. C., Alexander, A. Y., Agosti, E., Vilany, L., Graepel, S., Choby, G., & D., C. (2022). Surgical Anatomy and Approaches of the Anterior Cranial Fossa from a Transcranial and Endonasal Perspective. Cancers, 15(9), 2587. https://doi.org/10.3390/cancers15092587
17. Borghei-Razavi, H.; Eguiluz-Melendez, A.; Wenping, X.; Truong, H.Q.; Fernandes-Cabral, D.; Najera, E.; Stefko, T.; Fernandez-Miranda, J.C.; Gardner, P.A. Surgical Limitations of the Microscopic Transciliary Supraorbital Keyhole Approach to the Anterior and Middle Skull Base. World Neurosurg. 2022, 167, e1440–e1447.
18. Da Costa, M.D.S.; Hardesty, D.A.; Priddy, B.; Noiphithak, R.; RevueltaBarbero, J.M.; Prevedello, D.M. Extended Supraorbital Approach with Modified Eyebrow Incision: Technical Note. World Neurosurg. 2019, 128, 354–359.
19. Pinheiro-Neto, C.D.; Peris-Celda, M.; Kenning, T. Extrapolating the Limits of the Nasoseptal Flap with Pedicle Dissection to the Internal Maxillary Artery. Oper. Neurosurg. 2019, 16, 37–44
20. Pinheiro-Neto, C.; Rowan, N.R.; Celda, M.P.; Mukherjee, D.; Gompel, J.J.V.; Choby, G. Optimizing Quality of Life and Minimizing Morbidity through Nasal Preservation in Endoscopic Skull Base Surgery: A Contemporary Review. J. Neurol. Surg. B Skull Base 2022, 83, 602–610