BIOPHYSICAL CHARACTERIZATION AND BIOLOGICAL APPLICATIONS OF SILVER NANOPARTICLES DERIVED FROM FICUS CARICA
Main Article Content
Keywords
silver nanoparticles, Ficus carica, biophysical characterization, biological applications
Abstract
Silver nanoparticles (AgNPs) have gained significant attention due to their unique physicochemical properties and diverse biological activities. In the study, exploration was conducted into the biophysical characterization and biological application of AgNPs derived from Ficus carica. The synthesized nanoparticles were characterized using various techniques, including UV-visible spectroscopy, scanning electron microscopy, Fourier-transform infrared spectroscopy, and X-ray diffraction. The biological activity of AgNPs derived from F. carica was assessed using different microbes. Their antimicrobial potential against bacteria and fungi was evaluated, along with cytotoxicity and antileishmanial activity. The results of this study contribute to the expanding knowledge based on the synthesis and application of silver nanoparticles, specifically those derived from Ficus carica, and highlight their potential for diverse biomedical applications.
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33. Phanjom, Probin, et al. "Plant-mediated synthesis of silver nanoparticles using Elaeagnus latifolia leaf extract." Digest Journal of Nanomaterials and Biostructures 7.3 (2012): 1117-1123.
34. Aldebasi, Yousef H., et al. "Noble silver nanoparticles (AgNPs) synthesis and characterization of fig Ficus carica (fig) leaf extract and its antimicrobial effect against clinical isolates from corneal ulcer." African Journal of Biotechnology 13.45 (2014).
35. Logaranjan, K., S. Devi, and K. Pandian. "Biogenic Synthesis of Silver Nanoparticles Using Fruit Extract of Ficus Carica and Study Its Antimicrobial Activity." Nano Biomedicine & Engineering 4.4 (2012).
36. Acay, H. "Biosynthesis and characterization of silver nanoparticles using fig (Ficus carica) leaves: a potential antimicrobial activity." Applied Ecology & Environmental Research 17.6 (2019).
37. Acay, H. "Biosynthesis and characterization of silver nanoparticles using fig (Ficus carica) leaves: a potential antimicrobial activity." Applied Ecology & Environmental Research 17.6 (2019).
38. Aldebasi, Yousef H., et al. "Noble silver nanoparticles (AgNPs) synthesis and characterization of fig Ficus carica (fig) leaf extract and its antimicrobial effect against clinical isolates from corneal ulcer." African Journal of Biotechnology 13.45 (2014).
39. Logaranjan, K., S. Devi, and K. Pandian. "Biogenic Synthesis of Silver Nanoparticles Using Fruit Extract of Ficus Carica and Study Its Antimicrobial Activity." Nano Biomedicine & Engineering 4.4 (2012).
40. Acay, H. "Biosynthesis and characterization of silver nanoparticles using fig (Ficus carica) leaves: a potential antimicrobial activity." Applied Ecology & Environmental Research 17.6 (2019).
41. Almayouf, Mina A., et al. "The effects of silver nanoparticles biosynthesized using fig and olive extracts on cutaneous leishmaniasis-induced inflammation in female balb/c mice." Bioscience Reports 40.12 (2020): BSR20202672.
42. El-Khadragy, Manal, et al. "Clinical efficacy associated with enhanced antioxidant enzyme activities of silver nanoparticles biosynthesized using Moringa oleifera leaf extract, against cutaneous leishmaniasis in a murine model of Leishmania major." International journal of environmental research and public health 15.5 (2018): 1037.
43. Mohammadi, Mohsen, et al. "Efficacy of green synthesized silver nanoparticles via ginger rhizome extract against Leishmania major in vitro." PloS one 16.8 (2021): e0255571.
44. Rossi-Bergmann, Bartira, et al. "Therapeutic potential of biogenic silver nanoparticles in murine cutaneous leishmaniasis." Journal of Nano Research 20 (2012): 89-97.
45. Jebali, Ali, and Bahram Kazemi. "Nano-based antileishmanial agents: a toxicological study on nanoparticles for future treatment of cutaneous leishmaniasis." Toxicology in vitro 27.6 (2013): 1896-1904.
2. Ahmed, Shakeel, et al. "A review on plants extract mediated synthesis of silver nanoparticles for antimicrobial applications: a green expertise." Journal of advanced research 7.1 (2016): 17-28.
3. Chung, Ill-Min, et al. "Plant-mediated synthesis of silver nanoparticles: their characteristic properties and therapeutic applications." Nanoscale research letters 11 (2016): 1-14.
4. Ayeni, Emmanuel Ayodeji, et al. "Medicinal plants for anti-neurodegenerative diseases in West Africa." Journal of Ethnopharmacology 285 (2022): 114468.
5. Logaranjan, K., S. Devi, and K. Pandian. "Biogenic Synthesis of Silver Nanoparticles Using Fruit Extract of Ficus Carica and Study Its Antimicrobial Activity." Nano Biomedicine & Engineering 4.4 (2012).
6. Nasar, Sidra, et al. "Green approach to synthesis of silver nanoparticles using Ficus Palmata leaf extract and their antibacterial profile." Pharmaceutical Chemistry Journal 51 (2017): 811-817.
7. Acay, H. "Biosynthesis and characterization of silver nanoparticles using fig (Ficus carica) leaves: a potential antimicrobial activity." Applied Ecology & Environmental Research 17.6 (2019).
8. Goyal, Shivangi, et al. "Antibacterial, anticancer and antioxidant potential of silver nanoparticles engineered using Trigonella foenum‐graecum seed extract." IET nanobiotechnology 12.4 (2018): 526-533.
9. Alharbi, Njud S., Nehad S. Alsubhi, and Afnan I. Felimban. "Green synthesis of silver nanoparticles using medicinal plants: Characterization and application." Journal of Radiation Research and Applied Sciences 15.3 (2022): 109-124.
10. AlMasoud, Najla, et al. "Green nanotechnology synthesized silver nanoparticles: Characterization and testing its antibacterial activity." Green Processing and Synthesis 10.1 (2021): 518-528.
11. Badgujar, Shamkant B., et al. "Traditional uses, phytochemistry and pharmacology of Ficus carica: A review." Pharmaceutical biology 52.11 (2014): 1487-1503.
12. Mawa, Shukranul, Khairana Husain, and Ibrahim Jantan. "Ficus carica L.(Moraceae): phytochemistry, traditional uses and biological activities." Evidence-Based Complementary and Alternative Medicine 2013 (2013).
13. Ivanova, Nadezhda, et al. Silver nanoparticles as multi-functional drug delivery systems. London, UK: IntechOpen, 2018.
14. Anjum, Sumaira, Bilal Haider Abbasi, and Zabta Khan Shinwari. "Plant-mediated green synthesis of silver nanoparticles for biomedical applications: Challenges and opportunities." Pak. J. Bot 48.4 (2016): 1731-1760.
15. Habeeb Rahuman, Haajira Beevi, et al. "Medicinal plants mediated the green synthesis of silver nanoparticles and their biomedical applications." IET nanobiotechnology 16.4 (2022): 115-144.
16. Rajeshkumar, S., L. V. Bharath, and R. Geetha. "Broad spectrum antibacterial silver nanoparticle green synthesis: Characterization, and mechanism of action." Green synthesis, characterization and applications of nanoparticles. Elsevier, 2019. 429-444.
17. Park, Youmie. "A new paradigm shift for the green synthesis of antibacterial silver nanoparticles utilizing plant extracts." Toxicological research 30 (2014): 169-178.
18. Rajan, Ramachandran, et al. "Plant extract synthesized silver nanoparticles: an ongoing source of novel biocompatible materials." Industrial Crops and Products 70 (2015): 356-373.
19. Wahab, Shahid, et al. "Mechanistic aspects of plant-based silver nanoparticles against multi-drug resistant bacteria." Heliyon 7.7 (2021).
20. Patil, Maheshkumar Prakash, and Gun-Do Kim. "Eco-friendly approach for nanoparticles synthesis and mechanism behind antibacterial activity of silver and anticancer activity of gold nanoparticles." Applied microbiology and biotechnology 101 (2017): 79-92.
21. Prasad, S. R., et al. "A review on bio-inspired synthesis of silver nanoparticles: their antimicrobial efficacy and toxicity." Engineered Science 16 (2021): 90-128.
22. Ahmed, Shakeel, et al. "A review on plants extract mediated synthesis of silver nanoparticles for antimicrobial applications: a green expertise." Journal of advanced research 7.1 (2016): 17-28.
23. Jain, Ashvi Sanjay, et al. "Bionanofactories for green synthesis of silver nanoparticles: Toward antimicrobial applications." International Journal of Molecular Sciences 22.21 (2021): 11993.
24. Firdhouse, M. Jannathul, and P. Lalitha. "Biosynthesis of silver nanoparticles and its applications." Journal of Nanotechnology 2015 (2015).
25. Nafiu, M. O., et al. "Preparation, standardization, and quality control of medicinal plants in Africa." Medicinal spices and vegetables from Africa (2017): 171-204.
26. Weli, Afaf Mohammed, Afaf Ali Mohammed Al-Blushi, and Mohammad Amzad Hossain. "Evaluation of antioxidant and antimicrobial potential of different leaves crude extracts of Omani Ficus carica against food borne pathogenic bacteria." Asian Pacific Journal of Tropical Disease 5.1 (2015): 13-16.
27. Ulug, Bulent, et al. "Role of irradiation in the green synthesis of silver nanoparticles mediated by fig (Ficus carica) leaf extract." Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 135 (2015): 153-161.
28. Logaranjan, K., S. Devi, and K. Pandian. "Biogenic Synthesis of Silver Nanoparticles Using Fruit Extract of Ficus Carica and Study Its Antimicrobial Activity." Nano Biomedicine & Engineering 4.4 (2012).
29. Arumugam, J., et al. "Green synthesis of zinc oxide nanoparticles using Ficus carica leaf extract and their bactericidal and photocatalytic performance evaluation." Chemical Physics Letters 783 (2021): 139040.
30. Saxena, Antariksh, et al. "Green synthesis of silver nanoparticles using aqueous solution of Ficus benghalensis leaf extract and characterization of their antibacterial activity." Materials letters 67.1 (2012): 91-94.
31. Paul, Nilesh S., and Raman P. Yadav. "Biosynthesis of silver nanoparticles using plant seeds and their antimicrobial activity." Asian Journal of Biomedical and Pharmaceutical Sciences 5.45 (2015): 26.
32. Arumugam, Nagarajan, et al. "Biogenesis of silver nanoparticles using selected plant leaf extract; characterization and comparative analysis of their antimicrobial activity." Nanomedicine Journal 4.4 (2017).
33. Phanjom, Probin, et al. "Plant-mediated synthesis of silver nanoparticles using Elaeagnus latifolia leaf extract." Digest Journal of Nanomaterials and Biostructures 7.3 (2012): 1117-1123.
34. Aldebasi, Yousef H., et al. "Noble silver nanoparticles (AgNPs) synthesis and characterization of fig Ficus carica (fig) leaf extract and its antimicrobial effect against clinical isolates from corneal ulcer." African Journal of Biotechnology 13.45 (2014).
35. Logaranjan, K., S. Devi, and K. Pandian. "Biogenic Synthesis of Silver Nanoparticles Using Fruit Extract of Ficus Carica and Study Its Antimicrobial Activity." Nano Biomedicine & Engineering 4.4 (2012).
36. Acay, H. "Biosynthesis and characterization of silver nanoparticles using fig (Ficus carica) leaves: a potential antimicrobial activity." Applied Ecology & Environmental Research 17.6 (2019).
37. Acay, H. "Biosynthesis and characterization of silver nanoparticles using fig (Ficus carica) leaves: a potential antimicrobial activity." Applied Ecology & Environmental Research 17.6 (2019).
38. Aldebasi, Yousef H., et al. "Noble silver nanoparticles (AgNPs) synthesis and characterization of fig Ficus carica (fig) leaf extract and its antimicrobial effect against clinical isolates from corneal ulcer." African Journal of Biotechnology 13.45 (2014).
39. Logaranjan, K., S. Devi, and K. Pandian. "Biogenic Synthesis of Silver Nanoparticles Using Fruit Extract of Ficus Carica and Study Its Antimicrobial Activity." Nano Biomedicine & Engineering 4.4 (2012).
40. Acay, H. "Biosynthesis and characterization of silver nanoparticles using fig (Ficus carica) leaves: a potential antimicrobial activity." Applied Ecology & Environmental Research 17.6 (2019).
41. Almayouf, Mina A., et al. "The effects of silver nanoparticles biosynthesized using fig and olive extracts on cutaneous leishmaniasis-induced inflammation in female balb/c mice." Bioscience Reports 40.12 (2020): BSR20202672.
42. El-Khadragy, Manal, et al. "Clinical efficacy associated with enhanced antioxidant enzyme activities of silver nanoparticles biosynthesized using Moringa oleifera leaf extract, against cutaneous leishmaniasis in a murine model of Leishmania major." International journal of environmental research and public health 15.5 (2018): 1037.
43. Mohammadi, Mohsen, et al. "Efficacy of green synthesized silver nanoparticles via ginger rhizome extract against Leishmania major in vitro." PloS one 16.8 (2021): e0255571.
44. Rossi-Bergmann, Bartira, et al. "Therapeutic potential of biogenic silver nanoparticles in murine cutaneous leishmaniasis." Journal of Nano Research 20 (2012): 89-97.
45. Jebali, Ali, and Bahram Kazemi. "Nano-based antileishmanial agents: a toxicological study on nanoparticles for future treatment of cutaneous leishmaniasis." Toxicology in vitro 27.6 (2013): 1896-1904.
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May 14, 2024
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Nighat Nawaz, Irshad Ahmad, & Iqbal Hussain. (2024). BIOPHYSICAL CHARACTERIZATION AND BIOLOGICAL APPLICATIONS OF SILVER NANOPARTICLES DERIVED FROM FICUS CARICA. Journal of Population Therapeutics and Clinical Pharmacology, 31(5), 656-667. https://doi.org/10.53555/jptcp.v31i5.6216
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Author Biographies
Nighat Nawaz
Department of Chemistry, Islamia College Peshawar, Pakistan
Irshad Ahmad
Institute of Basic Medical Sciences, Khyber Medical University Peshawar, Pakistan
Iqbal Hussain
Department of Chemistry, Islamia College Peshawar, Pakistan
How to Cite
Nighat Nawaz, Irshad Ahmad, & Iqbal Hussain. (2024). BIOPHYSICAL CHARACTERIZATION AND BIOLOGICAL APPLICATIONS OF SILVER NANOPARTICLES DERIVED FROM FICUS CARICA. Journal of Population Therapeutics and Clinical Pharmacology, 31(5), 656-667. https://doi.org/10.53555/jptcp.v31i5.6216