SPECTRUM OF PEDIATRIC GASTROINTESTINAL ENDOSCOPY

Main Article Content

Hafsa Zaheer
Mahnaz Hakeem
Ambreen Raza
Sana Samreen
Sajid Soofi
Kamran Sadiq

Keywords

Paediatric, Gastrointestinal Endoscopy, Gastritis, Abdominal pain, H.pylori

Abstract

Background &Objective


In History first gastroscope was made by Adolf Kussmaul in 1868 with the help of professional sword swallower to pass a tube into his stomach. Later, In 1881 Johann von Mikulicz and his colleagues introduced the first practical rigid gastroscope. Then, in 1932, Dr. Rudolph Schindler invented flexible gastroscope,however, the real breakthrough in endoscopy emerged in the 1950s with the development of glass fiber technology, and Basil Hirschowitz is credited with creating the first flexible fiber-optic endoscope in 1957. These innovations led to the widespread adoption of endoscopy as a standard diagnostic and therapeutic tool in gastroenterology units worldwide. In the early 1970s, further advancements in endoscope size reduction paved the way for pediatricians to begin using this tool as diagnostic modality. (1,2)


This field has grown exponentially in developed countries however literature search showed limited work has been done in developing countries so far.(5,6)This study aimed to identify prevalent reasons for conducting pediatric GI endoscopy and the typical endoscopic observations in children, with the ultimate goal of enhancing awareness and improving outcomes for gastrointestinal disorders in our population.


Methods


A comprehensive review was conducted on the medical records of 139 pediatric patients, aged 1 to 16 years, who had undergone gastrointestinal endoscopy at Aga Khan University Hospital. Infants were excluded from this analysis. The study gathered information regarding patient demographics, the reasons for the endoscopy as determined by the treating clinicians, the results of the procedure, whether it was performed by a pediatric or adult gastroenterologist, the type of anesthesia administered (sedation or general anesthesia), peri-procedural antibiotics prophylaxis if given, any complications that occurred during or after the procedure, and the histopathological findings obtained.


Results


Recurrent abdominal pain was the primary reason for GI endoscopy in 22.3% of cases, with gastritis being the most prevalent endoscopic finding in 30.2%. The most frequent histopathological finding, found in 23.5% of cases, was gastritis associated with H. pylori. Anesthesia and conscious sedation were administered for the procedures, which took place in various settings, including the operating theater, surgical day care, and endoscopic suites. No immediate complications were observed following the procedures in any of the cases.


Conclusion


Gastrointestinal endoscopy is a reliable and safe procedure that serves as a valuable tool for both diagnosis and treatment.

Abstract 85 | PDF Downloads 32

References

1. Cox CB, Laborda T, Kynes JM, Hiremath G. Evolution in the practice of pediatric endoscopy and sedation. Front Pediatr. 2021 Jul 14; 9:687635.
DOI:https://doi.org/10.3389/fped.2021.687635
2. Rahman I, Patel P, Boger P, Rasheed S, Thomson M, Afzal NA. Therapeutic upper gastrointestinal tract endoscopy in Paediatric Gastroenterology. World J GastrointestEndosc. 2015 Mar 3; 7(3):169.
DOI: 10.4253/wjge.v7.i3.169
3. Khan MR, Ahmed S, Ali SR, Maheshwari PK, Jamal MS. Spectrum of upper GI endoscopy in pediatric population at a tertiary care centre in Pakistan. Open J Pediatr. 2014 Aug 15; 2014.
DOI: 10.4236/ojped.2014.43025
4. Ullah I, Naeem M, Bilal M, Sajjad S, Ahmad OH, Zaheer S. Importance and role of upper gastrointestinal endoscopy in Diagnosis of recurrent abdominal pain in children. Pak J Med Sci . 2022 May 31;16(03):1209
DOI:https://doi.org/10.53350/pjmhs221631209
5. Tringali A, Thomson M, Dumonceau JM, Tavares M, Tabbers MM, Furlano R et, al. Pediatric gastrointestinal endoscopy: European society of gastrointestinal endoscopy (ESGE) and European society for paediatric gastroenterology hepatology and nutrition (ESPGHAN) guideline executive summary. Endoscopy. 2017 Jan; 49(01):83-91.
DOI: 10.1055/s-0042-111002
6. Franciosi JP, Fiorino K, Ruchelli E, Shults J, Spergel J, Liacouras CA et, al. Changing indications for upper endoscopy in children over a 20 year period. J Pediatr Gastroenterol Nutr. 2010 Oct; 51(4):443.
DOI:10.1097/MPG.0b013e3181d67bee
7. Lang T. Interfaces in pediatric gastrointestinal endoscopy: Who Should Do It?Viszeralmedizin. 2016 Feb 1; 32(1):7-11.
DOI: https://doi.org/10.1159/000444116
8. Walsh CM, Lightdale JR. Pediatric Endoscopy Quality Improvement Network (PEnQuIN) quality standards and indicators for pediatric endoscopy: an ASGE-endorsed guideline.GastrointestEndosc. 2022 Oct 1; 96(4):593-602.
DOI:https://doi.org/10.1016/j.gie.2022.06.016
9. Scarallo L, Russo G, Renzo S, Lionetti P, Oliva S. A journey towards pediatric gastrointestinal endoscopy and its training: a narrative review. Front Pediatr. 2023 Jan 1; 11:1201593.
DOI: 10.3389/fped.2023.1201593
10. Broekaert I, Tzivinikos C, Narula P, Antunes H, Dias JA, van der Doef H et, al. European Society for Paediatric Gastroenterology, Hepatology and Nutrition position paper on training in paediatric endoscopy. J Pediatr Gastroenterol Nutr. 2020 Jan 1;70(1):127-DOI: 10.1097/MPG.0000000000002496
11. Fachler T, Shteyer E, Orlanski Meyer E, Shemasna I, Lev Tzion R, Rachman Y et, al. Pediatric Gastrointestinal Endoscopy: diagnostic yield and appropriateness of referral based on clinical presentation: A Pilot Study. Front Pediatr. 2021 Oct 29; 9:607418.
DOI: https://doi.org/10.3389/fped.2021.607418
12. Schreiber-Dietrich D, Hocke M, Braden B, Carrara S, Gottschalk U, Dietrich CF. Pediatric endoscopy, update 2020. Appl Sci. 2019 Nov 22; 9(23):5036.
DOI:https://doi.org/10.3390/app9235036
13. Isa H, Alfayez F. Indications and yield of Pediatric endoscopy in Bahrain: A tertiary center experience. Int J Pediatr, 2022 Mar 26;2022
DOI: https://doi.org/10.1155/2022/6836842
14. Lightdale JR, Acosta R, Shergill AK, Chandrasekhara V, Chathadi K, Early D et, al. Modifications in endoscopic practice for pediatric patients.GastrointestEndosc, 2014 May 1;79(5):699-710
DOI:https://doi.org/10.1016/j.gie.2013.08.014
15. Birk M, Bauerfeind P, Deprez PH, Häfner M, Hartmann D, Hassan C, Hucl T, LesurAabakken L, Meining A. Removal of foreign bodies in the upper gastrointestinal tract in adults: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline. Endoscopy. 2016 Feb 10:489-96..Early DS, Lightdale JR, Vargo JJ, Acosta RD, Chandrasekhara V, Chathadi KV et, Guidelines for sedation and anesthesia in GI endoscopy. GastrointestEndosc, 2018 Feb 1; 87(2):327-37.
DOI: https://doi.org/10.1016/j.gie.2017.07.018
16. .Hartjes KT, Dafonte TM, Lee AF, Lightdale JR. Variation in pediatric anesthesiologist sedation practices for pediatric gastrointestinal endoscopy. Front Pediatr. 2021 Aug 11; 9:709433.
DOI:https://doi.org/10.3389/fped.2021.709433
17. Pall H, Lerner D, Khlevner J, Reynolds C, Kurowski J, Troendle D et, al. Developing the pediatric gastrointestinal endoscopy unit: a clinical report by the endoscopy and procedures committee. J Pediatr Gastroenterol Nutr, 2016 Aug 1; 63(2):295-306.
DOI: 10.1097/MPG.0000000000001189
18. Attard, T.M., Grima, AM. & Thomson, M. Pediatric endoscopic procedure complications. Curr Gastroenterol Rep 20, 48 (2018).
DOI:https://doi.org/10.1007/s11894-018-0646-5
19. .Tringali A, Balassone V, De Angelis P, Landi R. Complications in pediatric endoscopy.Best Pract Res Clin Gastroenterol. 2016 Oct 1;30(5):825-39.
DOI: https://doi.org/10.1007/s11894-018-0646-5
20. Lightdale JR, Liu QY, Sahn B, Troendle DM, Thomson M, Fishman DS. Pediatric endoscopy and high-risk patients: a clinical report from the NASPGHAN endoscopy committee. J Pediatr Gastroenterol Nutr. 2019 Apr; 68(4):595.
DOI: 10.1097/MPG.0000000000002277
21. .Khashab MA, Chithadi KV, Acosta RD, Bruining DH, Chandrasekhara V, Eloubeidi MA et, al. Antibiotic prophylaxis for GI endoscopy. Gastrointest Endosc, 2015 Jan ; 81(1):81-9.
DOI:https://doi.org/10.1016/j.gie.2014.08.008
22. Wani MA, Zargar SA, Yatoo GN, Haq I, Shah A, Sodhi JS et al. Endoscopic yield, appropriateness, and complications of pediatric upper gastrointestinal endoscopy in an adult suite: a retrospective study of 822 children. Clin Endosc, 2020 Apr 7; 53(4):436-42.
DOI: https://doi.org/10.5946/ce.2019.118
23. Atimati AO, Ewah-Odiase RO, Irowa OO. Paediatric Gastrointestinal endoscopy in a Nigerian tertiary hospital. Ann Med Health Sci Res. 2022 Dec 23; 8(4):288-96.
DOI: https://doi.org/10.30442/ahr.0804-05-180
24. Burayzat S, Odeh M, Altamimi E, Al-Dweik S, El Wahab K, AlanaswehM et, al. Esophagogastroduodenoscopy in pediatrics: does abiding by the international guidelines lead to appropriate management? A cross-sectional study. BMJ open. 2022 Sep 1; 12(9):e061489.
DOI:http://dx.doi.org/10.1136/bmjopen-2022-061489
25. Wang S, Qiu X, Chen J, Mei H, Yan H, You J, Huang Y. Pediatric esophagogastroduodenoscopy in china: indications, diagnostic yield, and factors associated with findings. BMC Pediatr. 2022 Dec; 22(1):1-8.
DOI:https://doi.org/10.1186/s12887-022-03558-x
26. .Arslan M, Isik H, Balamtekin N. Are Indications and Findings of Upper Gastrointestinal System Endoscopy Changing in Children Over the Years?/CocuklardaYillarIcindeUst Gastrointestinal System Endoskopi Endikasyonlarive Bulgulari Degisiyor Mu?. J CurrPediatr. 2021 Dec 1;19(3):285-92.
DOI:https://doi.org/10.4274/jcp.2021.02359
27. Adeniyi OF, Odeghe EA, Lawal MA, Olowu AO, Ademuyiwa A. Recurrent abdominal pain and upper gastrointestinal endoscopy findings in children and adolescents presenting at the Lagos University Teaching Hospital. PloS one. 2019 May 23; 14(5):e0216394.
DOI: https://doi.org/10.1371/journal.pone.0216394

Most read articles by the same author(s)