Exploring Socio-Demographic Determinants and Geographical Variations in Epidemiological Patterns of Hepatitis C: A Nationwide Analysis
Main Article Content
Keywords
Hepatitis C, epidemiology, socio-demographic determinants, geographical variations, nationwide analysis.
Abstract
Hepatitis C infection is a significant public health concern globally, with variations observed across socio-demographic factors and geographical regions. Understanding these determinants and variations is crucial for effective disease management and prevention strategies.
Aim: This study aimed to explore the socio-demographic determinants and geographical variations in the epidemiological patterns of Hepatitis C infection on a nationwide scale.
Methods: A comprehensive nationwide analysis was conducted using epidemiological data collected from diverse sources. Socio-demographic variables including age, gender, income levels, and educational attainment were analyzed alongside geographical factors such as urbanization and regional disparities. Statistical methods including regression analysis and geographic mapping were employed to assess the relationships between these variables and the incidence/prevalence rates of Hepatitis C.
Results: The analysis revealed notable socio-demographic determinants influencing the epidemiological patterns of Hepatitis C. Factors such as lower income levels, educational disparities, and certain age groups were associated with higher prevalence rates. Additionally, geographical variations highlighted hotspots of infection prevalence, with certain regions exhibiting significantly higher rates compared to others.
Conclusion: This nationwide analysis provides valuable insights into the socio-demographic determinants and geographical variations affecting the epidemiological patterns of Hepatitis C. The findings underscore the importance of targeted interventions tailored to specific demographic groups and geographical regions for effective disease control and prevention efforts
References
2. Grandi G, Lopez LF, Burattini MN. Regional differences and temporal trend analysis of Hepatitis B in Brazil. BMC Public Health. 2022 Oct 17;22(1):1931.
3. Xiao S, Xie W, Zhang Y, Lei L, Pan Y. Changing epidemiology of cirrhosis from 2010 to 2019: results from the Global Burden Disease study 2019. Annals of Medicine. 2023 Dec 12;55(2):2252326.
4. Lankarani KB, Honarvar B, Davoodi A, Asmarian N, Serati MR, Akbarpour MA, Sadeghi E, Moghadam TN, Vardanjani HM. Hepatitis A Chronic Immunity in Iran: A Geographic Information System-Based Study. Hepatitis Monthly. 2023 Dec 31(In Press).
5. Tabak F, Şirin G, Demir M, Aladağ M, Sümer Ş, Kurtaran B, Tosun S, Yamazhan T, Gürbüz Y. Demographic Characteristics and Transmission Risk Factors of Patients with Hepatitis C Virus in Turkey: The EPI-C, A Multicenter and Cross-sectional Trial.
6. Jing W, Liu J, Liu M. The global trends and regional differences in incidence of HEV infection from 1990 to 2017 and implications for HEV prevention. Liver International. 2021 Jan;41(1):58-69.
7. Jing W, Liu J, Liu M. The global trends and regional differences in incidence of HEV infection from 1990 to 2017 and implications for HEV prevention. Liver International. 2021 Jan;41(1):58-69.
8. Park JJ, Lee M, Kim H, Park JY, Lee H, Kim HJ, Koyanagi A, Smith L, Kim MS, Rahmati M, Rhee SY. National trends in the prevalence of hepatitis B and C in South Korea, before and during the COVID-19 pandemic (2007-2021)–a nationwide representative study. European Review for Medical & Pharmacological Sciences. 2023 Dec 15;27(24).
9. Alassad A, Rahwanji A, Jawad M, Yousfan A, Al Moualem S, Farhat A, Youssef LA. Seroprevalence and trends of hepatitis B virus, hepatitis C virus and human immunodeficiency virus in Syrian blood donors at Damascus University Blood Center between 2004 and 2021. Frontiers in Public Health. 2023 Jun 1;11:1174638.
10. Li J, Wang J, Nicholas S, Maitland E, Fei T. Regional differences of hepatitis B discrimination in rural China. Human Vaccines & Immunotherapeutics. 2021 Jul 3;17(7):2257-67.
11. Cao G, Jing W, Liu J, Liu M. The global trends and regional differences in incidence and mortality of hepatitis A from 1990 to 2019 and implications for its prevention. Hepatology international. 2021 Oct;15(5):1068-82.
12. Barat S, Parchure R, Darak S, Kulkarni V, Paranjape A, Gajrani M, Yadav A, Kulkarni V. An agent-based digital twin for exploring localized non-pharmaceutical interventions to control covid-19 pandemic. Transactions of the Indian National Academy of Engineering. 2021 Jun;6(2):323-53.
13. Rajabi A, Sharafi H, Alavian SM. Harm reduction program and hepatitis C prevalence in people who inject drugs (PWID) in Iran: an updated systematic review and cumulative meta-analysis. Harm Reduction Journal. 2021 Dec;18:1-25.
14. Capelastegui F, Trickey A, Thompson LH, Reza T, Emmanuel F, Cholette F, Blanchard JF, Archibald C, Vickerman P, Lim AG. Risk factors of HIV and variation in access to clean needles among people who inject drugs in Pakistan. Pathogens and Global Health. 2023 Nov 17;117(8):696-707.
15. Maliko M, Su FH, Kamiza AB, Su MJ, Yeh CC. The association between hepatic viral infections and cancers: a cross-sectional study in the Taiwan adult population. Clinical and Experimental Medicine. 2024 Dec;24(1):1-3.
16. Wang Y, Xie N, Wang Z, Ding S, Hu X, Wang K. Spatio-temporal distribution characteristics of the risk of viral hepatitis B incidence based on INLA in 14 prefectures of Xinjiang from 2004 to 2019. Mathematical Biosciences and Engineering. 2023 Apr 1;20(6):10678-93.
17. Jeong J, Kim M, Choi J. Investigating the spatio-temporal variation of hepatitis A in Korea using a Bayesian model. Frontiers in Public Health. 2023 Jan 20;10:1085077.
18. Olorunsogo TO, Ogugua JO, Muonde M, Maduka CP, Omotayo O. Epidemiological statistical methods: A comparative review of their implementation in public health studies in the USA and Africa. World Journal of Advanced Research and Reviews. 2024;21(1):1479-95.
19. Bartholomew TS, Onugha J, Bullock C, Scaramutti C, Patel H, Forrest DW, Feaster DJ, Tookes HE. Baseline prevalence and correlates of HIV and HCV infection among people who inject drugs accessing a syringe services program; Miami, FL. Harm reduction journal. 2020 Dec;17:1-8.
20. Bartholomew TS, Onugha J, Bullock C, Scaramutti C, Patel H, Forrest DW, Feaster DJ, Tookes HE. Baseline prevalence and correlates of HIV and HCV infection among people who inject drugs accessing a syringe services program; Miami, FL. Harm reduction journal. 2020 Dec;17:1-8.
21. Alzahrani MS. Healthcare Resources Utilization, Inpatient Mortality, and Risk Behaviors among Patients Infected with Hepatitis C Virus in the United States in the Era of Direct-Acting Antivirals (Doctoral dissertation, Howard University).
22. Recalde M, Rodríguez C, Burn E, Far M, García D, Carrere-Molina J, Benítez M, Moleras A, Pistillo A, Bolíbar B, Aragón M. Data resource profile: the information system for research in primary care (SIDIAP). International Journal of Epidemiology. 2022 Dec 1;51(6):e324-36.
23. Dwivedi SN, Shri N, Singh S. Disaster-Related Health Impacts and Endemic Disease among Middle-Aged Adults in India: Evidence from Longitudinal Ageing Survey of India (LASI), 2017-18. International Journal of Disaster Risk Reduction. 2024 Jan 1;100:104176.
24. Pereira FM, Salomão de Araujo A, Catarina Martins Reis A, Santos da Hora A, Pinotti F, Paton RS, Vilas Boas Figueiredo C, Lopes Damasceno C, Carlos dos Santos D, Souza de Santana D, Freitas Sales D. Dynamics and determinants of SARS-COV-2 RT-PCR testing on symptomatic individuals attending healthcare centers during 2020 in Bahia, Brazil. Viruses. 2022 Jul 15;14(7):1549.
25. Siljic M, Cirkovic V, Jovanovic L, Antonova A, Lebedev A, Ozhmegova E, Kuznetsova A, Vinogradova T, Ermakov A, Monakhov N, Bobkova M. Reconstructing the Temporal Origin and the Transmission Dynamics of the HIV Subtype B Epidemic in St. Petersburg, Russia. Viruses. 2022 Dec 9;14(12):2748.